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The map label for this gene is gpmI

Identifier: 74318412

GI number: 74318412

Start: 2466672

End: 2468213

Strand: Reverse

Name: gpmI

Synonym: Tbd_2394

Alternate gene names: 74318412

Gene position: 2468213-2466672 (Counterclockwise)

Preceding gene: 74318423

Following gene: 74318411

Centisome position: 84.82

GC content: 64.59

Gene sequence:

>1542_bases
ATGAAAGCCCTGCCGGTTCTCCTCATCATCCTCGACGGGTTTGGCTGCCGCGACGAACGCGCGAACAATGCGATTGCACA
GGCCAACAAGCCGAATTGGGACCGGCTCTGGAAGCACCATCCGCACACCCTCATCCACGCCTCCGAGTCGGAGGTCGGGC
TGCCGAAGGGGCAGATGGGCAATTCCGAGGTCGGCCATCTCAATATCGGGGCGGGGCGGGTCGTGTACCAGGAATTCACC
CGCATCGACCGCGCGATCGAGTCGGGTTACTTCTACACCAACCCGGCCTTGCTGAACGCCGTGCATCTGGCGCGCGACAA
CGGCAAGACCCTGCACGTCCTGGGCCTGCTGTCGGACGGCGGCGTGCACAGCCACGAGTTGCATTTCCATGCCCTGCTCG
ATCTGGCCGCGCGCGAGGGGCTCAGCAAGGTCTGCCTGCACGTGTTTCTCGATGGCCGCGACACGCCGCCCAAGAGCGCC
GAACTCTACCTGCGCCGCCTGACCGACAAGATAGCGCAGGCCGGGGTCGGTCATGTTGCGTCGATGATCGGCCGCTACTT
TGCGATGGACCGCGATCGTCGTTGGCAACGTGTGAAATCGGCCTACGACCTCCTGACTCAAGGCGCGGCCGAGTTCAGCG
CCGGGTCTGCACAGGCCGGACTCGAAGCGGCCTACGCGCGCGGCGAGACCGACGAGTTCGTCAAGGCGACCGCGATCGTG
CCGGCCGACGGCAGGCCGGTGACGATGGAGGACGGCGATTCGGTCATTTTCCTGAATTTCCGCTCCGACCGCGCACGCCA
ATTGTCGCGACCTTTCATCGAGCCCGACTTCAGCGAGTTCGAGCGTGAACGCACGCCGCGTCTGGCGACCTACTGCACGC
TGACCGGCTACAGCGACGATTTCGACGTGTCGGTCGCGTTCCCTCCCGAACGCATCAAGAACGGGCTCGGCGAATACGTC
GCCAACCTCGGGCTGCGCCAGTTGCGCATCGCCGAGACCGAGAAGTATCCGCACGTGACCTTCTTCTTCAACGGTGGCGA
GGAAGTGTCGTTCCCGGGCGAGGACCGCATCCTCGTGTCGTCGCCGGACGTCGCGACCTATGATCTCAAGCCTGAGATGA
GTGCCTTCGAGGTAACGGAAAAGCTGCTCGCCGCGATCGGCAGCAAGCAGTACGACCTCATCGTCTGCAACTACGCCAAT
CCCGACATGGTCGGCCACACCGGCAATCTCGAGGCGGCGATCAAGGCGATCGAGACCGTCGACACCTGCCTCGGCCGCGT
CGTCGAGGCGCAGCTCGCCCGCGGCGGCGAGGTCCTGATCACGGCTGACCACGGCAACGCCGAACTCATGCTCGACGCCG
AAACCGGCCAGGCGCACACCGCACACACCATGAATCTCGTGCCCGTGATCTTCGTCGGCCGTCGCCACGCGAGTCTGGCC
GAGACCGGGGCTCTGGAGGACGTCAGCCCGACGCTGCTCAGAATGATGGGTCTGCCGCAGCCACCCGAAATGAGCGGGGA
ATCGCTGCTTGCGTTCGAGTAA

Upstream 100 bases:

>100_bases
GCCACATTTCCCGCGACTTTGGCGGTCGCGTATAGATTAGCAATCACGCATATATTAAAATAATTCCTTGTAAACGAGTC
AGGTAATAACGAACTTTTTC

Downstream 100 bases:

>100_bases
ACGCGCGGCCCTTCGAGTAAGCGCGCGAGGGTGAACGGAAAACGCTTCCTCATCCTGTTGCTGCTCTGCCTGCCGCTGTA
CGCCGCGGCCGATCAGGCCA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKALPVLLIILDGFGCRDERANNAIAQANKPNWDRLWKHHPHTLIHASESEVGLPKGQMGNSEVGHLNIGAGRVVYQEFT
RIDRAIESGYFYTNPALLNAVHLARDNGKTLHVLGLLSDGGVHSHELHFHALLDLAAREGLSKVCLHVFLDGRDTPPKSA
ELYLRRLTDKIAQAGVGHVASMIGRYFAMDRDRRWQRVKSAYDLLTQGAAEFSAGSAQAGLEAAYARGETDEFVKATAIV
PADGRPVTMEDGDSVIFLNFRSDRARQLSRPFIEPDFSEFERERTPRLATYCTLTGYSDDFDVSVAFPPERIKNGLGEYV
ANLGLRQLRIAETEKYPHVTFFFNGGEEVSFPGEDRILVSSPDVATYDLKPEMSAFEVTEKLLAAIGSKQYDLIVCNYAN
PDMVGHTGNLEAAIKAIETVDTCLGRVVEAQLARGGEVLITADHGNAELMLDAETGQAHTAHTMNLVPVIFVGRRHASLA
ETGALEDVSPTLLRMMGLPQPPEMSGESLLAFE

Sequences:

>Translated_513_residues
MKALPVLLIILDGFGCRDERANNAIAQANKPNWDRLWKHHPHTLIHASESEVGLPKGQMGNSEVGHLNIGAGRVVYQEFT
RIDRAIESGYFYTNPALLNAVHLARDNGKTLHVLGLLSDGGVHSHELHFHALLDLAAREGLSKVCLHVFLDGRDTPPKSA
ELYLRRLTDKIAQAGVGHVASMIGRYFAMDRDRRWQRVKSAYDLLTQGAAEFSAGSAQAGLEAAYARGETDEFVKATAIV
PADGRPVTMEDGDSVIFLNFRSDRARQLSRPFIEPDFSEFERERTPRLATYCTLTGYSDDFDVSVAFPPERIKNGLGEYV
ANLGLRQLRIAETEKYPHVTFFFNGGEEVSFPGEDRILVSSPDVATYDLKPEMSAFEVTEKLLAAIGSKQYDLIVCNYAN
PDMVGHTGNLEAAIKAIETVDTCLGRVVEAQLARGGEVLITADHGNAELMLDAETGQAHTAHTMNLVPVIFVGRRHASLA
ETGALEDVSPTLLRMMGLPQPPEMSGESLLAFE
>Mature_513_residues
MKALPVLLIILDGFGCRDERANNAIAQANKPNWDRLWKHHPHTLIHASESEVGLPKGQMGNSEVGHLNIGAGRVVYQEFT
RIDRAIESGYFYTNPALLNAVHLARDNGKTLHVLGLLSDGGVHSHELHFHALLDLAAREGLSKVCLHVFLDGRDTPPKSA
ELYLRRLTDKIAQAGVGHVASMIGRYFAMDRDRRWQRVKSAYDLLTQGAAEFSAGSAQAGLEAAYARGETDEFVKATAIV
PADGRPVTMEDGDSVIFLNFRSDRARQLSRPFIEPDFSEFERERTPRLATYCTLTGYSDDFDVSVAFPPERIKNGLGEYV
ANLGLRQLRIAETEKYPHVTFFFNGGEEVSFPGEDRILVSSPDVATYDLKPEMSAFEVTEKLLAAIGSKQYDLIVCNYAN
PDMVGHTGNLEAAIKAIETVDTCLGRVVEAQLARGGEVLITADHGNAELMLDAETGQAHTAHTMNLVPVIFVGRRHASLA
ETGALEDVSPTLLRMMGLPQPPEMSGESLLAFE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=510, Percent_Identity=56.6666666666667, Blast_Score=595, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI32564249, Length=512, Percent_Identity=43.5546875, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17507741, Length=512, Percent_Identity=43.5546875, Blast_Score=397, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_THIDA (Q3SGA3)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316152.1
- ProteinModelPortal:   Q3SGA3
- SMR:   Q3SGA3
- STRING:   Q3SGA3
- GeneID:   3671439
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2394
- NMPDR:   fig|292415.3.peg.2467
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- PhylomeDB:   Q3SGA3
- ProtClustDB:   PRK05434
- BioCyc:   TDEN292415:TBD_2394-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 56323; Mature: 56323

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: ACT_SITE 62-62

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALPVLLIILDGFGCRDERANNAIAQANKPNWDRLWKHHPHTLIHASESEVGLPKGQMG
CCCCEEEEEEECCCCCCCCCCCCCHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCC
NSEVGHLNIGAGRVVYQEFTRIDRAIESGYFYTNPALLNAVHLARDNGKTLHVLGLLSDG
CCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHEECCCCCEEEEEEEECCC
GVHSHELHFHALLDLAAREGLSKVCLHVFLDGRDTPPKSAELYLRRLTDKIAQAGVGHVA
CCCCCHHHHHHHHHHHHHHCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
SMIGRYFAMDRDRRWQRVKSAYDLLTQGAAEFSAGSAQAGLEAAYARGETDEFVKATAIV
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCCCCCCHHCHHHHHHCCCCHHHEEEEEEE
PADGRPVTMEDGDSVIFLNFRSDRARQLSRPFIEPDFSEFERERTPRLATYCTLTGYSDD
CCCCCEEEEECCCEEEEEEECCHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEEECCCCC
FDVSVAFPPERIKNGLGEYVANLGLRQLRIAETEKYPHVTFFFNGGEEVSFPGEDRILVS
CEEEEECCHHHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEEECCCCEECCCCCCEEEEE
SPDVATYDLKPEMSAFEVTEKLLAAIGSKQYDLIVCNYANPDMVGHTGNLEAAIKAIETV
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
DTCLGRVVEAQLARGGEVLITADHGNAELMLDAETGQAHTAHTMNLVPVIFVGRRHASLA
HHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCEEEEECEEEEEECCCCCCHH
ETGALEDVSPTLLRMMGLPQPPEMSGESLLAFE
HCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MKALPVLLIILDGFGCRDERANNAIAQANKPNWDRLWKHHPHTLIHASESEVGLPKGQMG
CCCCEEEEEEECCCCCCCCCCCCCHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCC
NSEVGHLNIGAGRVVYQEFTRIDRAIESGYFYTNPALLNAVHLARDNGKTLHVLGLLSDG
CCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHEECCCCCEEEEEEEECCC
GVHSHELHFHALLDLAAREGLSKVCLHVFLDGRDTPPKSAELYLRRLTDKIAQAGVGHVA
CCCCCHHHHHHHHHHHHHHCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
SMIGRYFAMDRDRRWQRVKSAYDLLTQGAAEFSAGSAQAGLEAAYARGETDEFVKATAIV
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCCCCCCHHCHHHHHHCCCCHHHEEEEEEE
PADGRPVTMEDGDSVIFLNFRSDRARQLSRPFIEPDFSEFERERTPRLATYCTLTGYSDD
CCCCCEEEEECCCEEEEEEECCHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEEECCCCC
FDVSVAFPPERIKNGLGEYVANLGLRQLRIAETEKYPHVTFFFNGGEEVSFPGEDRILVS
CEEEEECCHHHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEEECCCCEECCCCCCEEEEE
SPDVATYDLKPEMSAFEVTEKLLAAIGSKQYDLIVCNYANPDMVGHTGNLEAAIKAIETV
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
DTCLGRVVEAQLARGGEVLITADHGNAELMLDAETGQAHTAHTMNLVPVIFVGRRHASLA
HHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCEEEEECEEEEEECCCCCCHH
ETGALEDVSPTLLRMMGLPQPPEMSGESLLAFE
HCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA