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The map label for this gene is ctpA [H]

Identifier: 74318410

GI number: 74318410

Start: 2463995

End: 2465401

Strand: Reverse

Name: ctpA [H]

Synonym: Tbd_2392

Alternate gene names: 74318410

Gene position: 2465401-2463995 (Counterclockwise)

Preceding gene: 74318411

Following gene: 74318409

Centisome position: 84.73

GC content: 64.82

Gene sequence:

>1407_bases
ATGACACAGAAGTCGAAATTCGTTCTCGTCGGTGTGGCCGGCGTGCTGGCGGGCGCTGCCCTCACGCTCAATCTTTCGGC
GATCGCCGACAAGGAGGCCGGGGCGCCGCTGCCAATCGAGGAGTTGCGCGCATTCACCGACGTGTTCGCGCGGGTCAAGA
ACGACTACGTCGAGCCGGTCGAGGACAAGAAACTCATCACCGAGGCGATCAACGGCATGCTGACCGGCCTCGATCCGCAC
TCCGCCTATCTCGACGTCGAGGGATTCAAGGACCTGCAGGTCGGGACCCAGGGCGAATTCGGCGGGCTGGGCATCGAAGT
CGGGATGGAAGAGGGCTTCATCAAGGTCGTTTCGCCGATCGAGGATACGCCCGCATTCAAGGCCGGCGTGAAGCCCGGCG
ACCTCATCGTCAAGCTCGACGACACCCCGGTGAAGGGCATGGCGCTCAACGACGCCGTCAAGCGCATGCGCGGCAAGCCG
GGTTCGAAAATCCGGCTCACCGTCGCGCGCAAGGGCGTCGACAAACCGATCGTGCTGACGCTCACGCGCGCGATCATCAA
GATCCGCAGCGTCAAGTCGAAGCTCATGGAAAGCGGCTACGGCTATGTGCGTGTCACCCAGTTCCAGGAGCACACCGGGG
AACTGCTGGCGGAAGCCCTGAACGCGCTGTACAAGAACAACAAGGCGCCGCTCAAGGGCCTCATCCTCGACCTGCGCAAC
GACCCCGGCGGTCTTCTCAACGGCGCGGTCGCCGTCACCGCAGCGTTCGTCAAGCCCGACGCACTCGTCGTCTACACCGA
GGGGCGCACGCCGGATGCCAAGATGCAGCTCACCGCGCGCCGCGAAAACTATCTGCGCCCGATGCAGGCGGACTACCTGA
AGAACCTGCCGCAGGGCGTGAAACAGGTGCCAATGGTCGTGCTCGTCAACAGCGGCTCGGCGTCGGCCTCGGAGATCGTG
GCCGGCGCGCTGCAGGACCACAAGCGCGCCGTGGTCATGGGCACGCGCACCTTCGGCAAGGGCTCGGTGCAGACCATCCT
GCCGCTCGGCAACGGCACCGCGATCAAGCTCACGACCGCCCGCTATTTCACGCCGAACGGGCGCTCGATCCAGGCCAAAG
GCATCGAACCCGACATCGTCGTCGAGGATCCGAGCATGCCGTCGGAAGACGACGGCCTCGGCATCCGCGAGGCCGACCTC
GCCAAGCACCTGGCCAATCCTTCCGACAAGGAGGGTACGTCCATCGTCGTGCCGGCCGACGACGAGGCCGGGCCCGCGGA
GCAGCCCTCGCGGGAAAGAAAGCCGCTCGCACCGCTCGAACCCGGTGAAATCGTGTCCAAGAACGATTTCCAGGTCAATC
AGGCGCTGAACCTGCTGAAAGGCCTGCAGATTCTCCAGGCGCACTGA

Upstream 100 bases:

>100_bases
GCCGCGGTGGGCAACAGCGGGGGCCAACCGGACTCCGGCCTGTACTTTGAAATGCGGCATCAGAGCCGCCCTGTTAATCC
CCTCGGGTGGGTGAAGTGAG

Downstream 100 bases:

>100_bases
GGCTGTCGACCTGCCGGCGCGTTCCCTGCCGGCAGCGTCCAACGCGGCTATACTGCATCTCACTAGTCTGTCGGGCCTGG
GCATGCGACCGTGTGATCTG

Product: peptidase S41A, protease

Products: NA

Alternate protein names: C-terminal-processing protease [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTQKSKFVLVGVAGVLAGAALTLNLSAIADKEAGAPLPIEELRAFTDVFARVKNDYVEPVEDKKLITEAINGMLTGLDPH
SAYLDVEGFKDLQVGTQGEFGGLGIEVGMEEGFIKVVSPIEDTPAFKAGVKPGDLIVKLDDTPVKGMALNDAVKRMRGKP
GSKIRLTVARKGVDKPIVLTLTRAIIKIRSVKSKLMESGYGYVRVTQFQEHTGELLAEALNALYKNNKAPLKGLILDLRN
DPGGLLNGAVAVTAAFVKPDALVVYTEGRTPDAKMQLTARRENYLRPMQADYLKNLPQGVKQVPMVVLVNSGSASASEIV
AGALQDHKRAVVMGTRTFGKGSVQTILPLGNGTAIKLTTARYFTPNGRSIQAKGIEPDIVVEDPSMPSEDDGLGIREADL
AKHLANPSDKEGTSIVVPADDEAGPAEQPSRERKPLAPLEPGEIVSKNDFQVNQALNLLKGLQILQAH

Sequences:

>Translated_468_residues
MTQKSKFVLVGVAGVLAGAALTLNLSAIADKEAGAPLPIEELRAFTDVFARVKNDYVEPVEDKKLITEAINGMLTGLDPH
SAYLDVEGFKDLQVGTQGEFGGLGIEVGMEEGFIKVVSPIEDTPAFKAGVKPGDLIVKLDDTPVKGMALNDAVKRMRGKP
GSKIRLTVARKGVDKPIVLTLTRAIIKIRSVKSKLMESGYGYVRVTQFQEHTGELLAEALNALYKNNKAPLKGLILDLRN
DPGGLLNGAVAVTAAFVKPDALVVYTEGRTPDAKMQLTARRENYLRPMQADYLKNLPQGVKQVPMVVLVNSGSASASEIV
AGALQDHKRAVVMGTRTFGKGSVQTILPLGNGTAIKLTTARYFTPNGRSIQAKGIEPDIVVEDPSMPSEDDGLGIREADL
AKHLANPSDKEGTSIVVPADDEAGPAEQPSRERKPLAPLEPGEIVSKNDFQVNQALNLLKGLQILQAH
>Mature_467_residues
TQKSKFVLVGVAGVLAGAALTLNLSAIADKEAGAPLPIEELRAFTDVFARVKNDYVEPVEDKKLITEAINGMLTGLDPHS
AYLDVEGFKDLQVGTQGEFGGLGIEVGMEEGFIKVVSPIEDTPAFKAGVKPGDLIVKLDDTPVKGMALNDAVKRMRGKPG
SKIRLTVARKGVDKPIVLTLTRAIIKIRSVKSKLMESGYGYVRVTQFQEHTGELLAEALNALYKNNKAPLKGLILDLRND
PGGLLNGAVAVTAAFVKPDALVVYTEGRTPDAKMQLTARRENYLRPMQADYLKNLPQGVKQVPMVVLVNSGSASASEIVA
GALQDHKRAVVMGTRTFGKGSVQTILPLGNGTAIKLTTARYFTPNGRSIQAKGIEPDIVVEDPSMPSEDDGLGIREADLA
KHLANPSDKEGTSIVVPADDEAGPAEQPSRERKPLAPLEPGEIVSKNDFQVNQALNLLKGLQILQAH

Specific function: Involved in protection of the bacterium from thermal and osmotic stresses (Potential) [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=383, Percent_Identity=29.7650130548303, Blast_Score=111, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 50048; Mature: 49917

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKSKFVLVGVAGVLAGAALTLNLSAIADKEAGAPLPIEELRAFTDVFARVKNDYVEPV
CCCCCCEEEEEHHHHHCCCEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
EDKKLITEAINGMLTGLDPHSAYLDVEGFKDLQVGTQGEFGGLGIEVGMEEGFIKVVSPI
HHHHHHHHHHHHHEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCC
EDTPAFKAGVKPGDLIVKLDDTPVKGMALNDAVKRMRGKPGSKIRLTVARKGVDKPIVLT
CCCCCHHCCCCCCCEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHH
LTRAIIKIRSVKSKLMESGYGYVRVTQFQEHTGELLAEALNALYKNNKAPLKGLILDLRN
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
DPGGLLNGAVAVTAAFVKPDALVVYTEGRTPDAKMQLTARRENYLRPMQADYLKNLPQGV
CCCCHHCCHHHEEEEEECCCEEEEEECCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHH
KQVPMVVLVNSGSASASEIVAGALQDHKRAVVMGTRTFGKGSVQTILPLGNGTAIKLTTA
HHCCEEEEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCEEEEEEE
RYFTPNGRSIQAKGIEPDIVVEDPSMPSEDDGLGIREADLAKHLANPSDKEGTSIVVPAD
EEECCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECC
DEAGPAEQPSRERKPLAPLEPGEIVSKNDFQVNQALNLLKGLQILQAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQKSKFVLVGVAGVLAGAALTLNLSAIADKEAGAPLPIEELRAFTDVFARVKNDYVEPV
CCCCCEEEEEHHHHHCCCEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
EDKKLITEAINGMLTGLDPHSAYLDVEGFKDLQVGTQGEFGGLGIEVGMEEGFIKVVSPI
HHHHHHHHHHHHHEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCC
EDTPAFKAGVKPGDLIVKLDDTPVKGMALNDAVKRMRGKPGSKIRLTVARKGVDKPIVLT
CCCCCHHCCCCCCCEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHH
LTRAIIKIRSVKSKLMESGYGYVRVTQFQEHTGELLAEALNALYKNNKAPLKGLILDLRN
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
DPGGLLNGAVAVTAAFVKPDALVVYTEGRTPDAKMQLTARRENYLRPMQADYLKNLPQGV
CCCCHHCCHHHEEEEEECCCEEEEEECCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHH
KQVPMVVLVNSGSASASEIVAGALQDHKRAVVMGTRTFGKGSVQTILPLGNGTAIKLTTA
HHCCEEEEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCEEEEEEE
RYFTPNGRSIQAKGIEPDIVVEDPSMPSEDDGLGIREADLAKHLANPSDKEGTSIVVPAD
EEECCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECC
DEAGPAEQPSRERKPLAPLEPGEIVSKNDFQVNQALNLLKGLQILQAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141685 [H]