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The map label for this gene is rtcB [C]

Identifier: 74318377

GI number: 74318377

Start: 2431807

End: 2433237

Strand: Reverse

Name: rtcB [C]

Synonym: Tbd_2359

Alternate gene names: 74318377

Gene position: 2433237-2431807 (Counterclockwise)

Preceding gene: 74318378

Following gene: 74318376

Centisome position: 83.62

GC content: 68.9

Gene sequence:

>1431_bases
ATGGATCTTGCGCGCTTGCAGCAGGCATCGGCGGTCGAGTGGCGGATCGGCCCGCACGGGCGCATGCGCGTGCCGGCCGT
CATCTTCGCCGACGAAGACCTGGTCCGCCAGATGGACGACAAGGTCTACGAGCAGATCACCCACGTTGCGGCGCTACCGG
GCATCGTCCAGGCAGCCTACGCCATGCCCGACGCCCACTGGGGCTACGGCTTTCCGATCGGCGGGGTCGCCGCCTTCGAC
GCCGACGAAGGCGGCGTCGTGTCCGCCGGCGGCGTCGGCTTCGACATCTCGTGCGGGGTGCGCACGCTACACACCGGCCT
CACCGTCGCCGACATTGCGCCGGTCAAGCAAAAACTGGCCGACCGCCTGTTCGCGAGCATCCCGGCGGGGGTCGGCAGTA
GCGGCAAGTTGCGTCTGAACAGCGTCGACATGGACGCGATGCTGCGCGGCGGCGCGTGCTGGGCCGTCGAGCGTGGCTAC
GGCAGTCCGGCCGACCTCGAGCGTATCGAGGAGCGCGGCTGCGTCGCGGGCGCCGCGCCCGAGCATGTCTCCGAGGCGGC
CAAGCGTCGCCAGCGCGACGAACTTGGCACGCTGGGCTCGGGCAACCATTACCTCGAACTGCAGGAAGTGACCCAGATCT
ACGACGTGCCCGCGGCCGACCGCTTCCGGCTTCGTGTCGGCGAACTCGTCGTCAGCATCCATTGCGGCTCGCGCGGACTC
GGGCACCAGATCGGGACCGAGTTTCTCAAGGCGATGGTGCTCGCGGCGCCTGCTCACGGCATCGATCTGCCCGACCGCGA
ACTCGCCTGCGCACCAATCGACTCGGCGCTCGGCCAGTCCTATCTCGGCGCGATGCGTGCCGCGACGAATTGCGCCCTCG
CCAATCGCGAGGTCATTACCCATCTCGTTCGCCAGGTTTTTGCGGATGTCGTCCCCGATTCCCACCTCGCGCTGGTCTAC
GACGTGTCGCACAACACCTGCAAGCAGGAGTCGTACACCGTCGACGGCAAGGCGAAACGTCTTTACGTCCATCGCAAGGG
CGCGACGCGTGCCTTCGGTCCGGGCCATCCCGGATTGCCCCCCGAACTTCGGGATATCGGCCAGCCCGTCATCGTCGGCG
GCAGCATGGGGACGGCCTCCTACATCCTCGTCGGTACCGAAGCGAGCCACCAGCTGGCCTTCAGCTCGGCCTGCCACGGC
GCCGGGCGCGCCATGAGCCGCCACCAGGCAAGCCGCACTTGGCATGGGCGGGCGCTCGTCGACGAACTCGCGGCCCAGGG
CGTGCTGATCCGCAGCCCGTCGTCGCGCGGCGTCGCCGAAGAAGCGCCGGGAGCCTACAAGGACGTCAGGGCGGTCGTCG
ACGCGGCGGACCGGGCCGGCCTCGCGCGCAAAGTTGCCAGGCTCAGGCCGCTCGTCTGCATCAAGGGCTGA

Upstream 100 bases:

>100_bases
CAACCCGTCGTCGAGATCAAGGGCGCGACCTATACTGGCCTGAAGGTAGGGAGAGACGAAACCGGGCAATGGCAGGCCCA
GTGCATCGTGGACGTGTGAC

Downstream 100 bases:

>100_bases
CCGCAGGGCCGGAACTGTCGTCGCGCCCGGGCGTCGAAAAAGCGTCTATCCAGCATGGAGCAACCGCGATGCCCTATAGC
GAACAAACCGTACAGTGGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MDLARLQQASAVEWRIGPHGRMRVPAVIFADEDLVRQMDDKVYEQITHVAALPGIVQAAYAMPDAHWGYGFPIGGVAAFD
ADEGGVVSAGGVGFDISCGVRTLHTGLTVADIAPVKQKLADRLFASIPAGVGSSGKLRLNSVDMDAMLRGGACWAVERGY
GSPADLERIEERGCVAGAAPEHVSEAAKRRQRDELGTLGSGNHYLELQEVTQIYDVPAADRFRLRVGELVVSIHCGSRGL
GHQIGTEFLKAMVLAAPAHGIDLPDRELACAPIDSALGQSYLGAMRAATNCALANREVITHLVRQVFADVVPDSHLALVY
DVSHNTCKQESYTVDGKAKRLYVHRKGATRAFGPGHPGLPPELRDIGQPVIVGGSMGTASYILVGTEASHQLAFSSACHG
AGRAMSRHQASRTWHGRALVDELAAQGVLIRSPSSRGVAEEAPGAYKDVRAVVDAADRAGLARKVARLRPLVCIKG

Sequences:

>Translated_476_residues
MDLARLQQASAVEWRIGPHGRMRVPAVIFADEDLVRQMDDKVYEQITHVAALPGIVQAAYAMPDAHWGYGFPIGGVAAFD
ADEGGVVSAGGVGFDISCGVRTLHTGLTVADIAPVKQKLADRLFASIPAGVGSSGKLRLNSVDMDAMLRGGACWAVERGY
GSPADLERIEERGCVAGAAPEHVSEAAKRRQRDELGTLGSGNHYLELQEVTQIYDVPAADRFRLRVGELVVSIHCGSRGL
GHQIGTEFLKAMVLAAPAHGIDLPDRELACAPIDSALGQSYLGAMRAATNCALANREVITHLVRQVFADVVPDSHLALVY
DVSHNTCKQESYTVDGKAKRLYVHRKGATRAFGPGHPGLPPELRDIGQPVIVGGSMGTASYILVGTEASHQLAFSSACHG
AGRAMSRHQASRTWHGRALVDELAAQGVLIRSPSSRGVAEEAPGAYKDVRAVVDAADRAGLARKVARLRPLVCIKG
>Mature_476_residues
MDLARLQQASAVEWRIGPHGRMRVPAVIFADEDLVRQMDDKVYEQITHVAALPGIVQAAYAMPDAHWGYGFPIGGVAAFD
ADEGGVVSAGGVGFDISCGVRTLHTGLTVADIAPVKQKLADRLFASIPAGVGSSGKLRLNSVDMDAMLRGGACWAVERGY
GSPADLERIEERGCVAGAAPEHVSEAAKRRQRDELGTLGSGNHYLELQEVTQIYDVPAADRFRLRVGELVVSIHCGSRGL
GHQIGTEFLKAMVLAAPAHGIDLPDRELACAPIDSALGQSYLGAMRAATNCALANREVITHLVRQVFADVVPDSHLALVY
DVSHNTCKQESYTVDGKAKRLYVHRKGATRAFGPGHPGLPPELRDIGQPVIVGGSMGTASYILVGTEASHQLAFSSACHG
AGRAMSRHQASRTWHGRALVDELAAQGVLIRSPSSRGVAEEAPGAYKDVRAVVDAADRAGLARKVARLRPLVCIKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=498, Percent_Identity=44.9799196787149, Blast_Score=395, Evalue=1e-110,
Organism=Escherichia coli, GI2367224, Length=442, Percent_Identity=27.8280542986425, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17506665, Length=438, Percent_Identity=46.5753424657534, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24585217, Length=498, Percent_Identity=45.7831325301205, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 50543; Mature: 50543

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLARLQQASAVEWRIGPHGRMRVPAVIFADEDLVRQMDDKVYEQITHVAALPGIVQAAY
CCHHHHHHCCCEEEEECCCCCEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMPDAHWGYGFPIGGVAAFDADEGGVVSAGGVGFDISCGVRTLHTGLTVADIAPVKQKLA
HCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEECCCHHHHHCCCCHHHHHHHHHHHH
DRLFASIPAGVGSSGKLRLNSVDMDAMLRGGACWAVERGYGSPADLERIEERGCVAGAAP
HHHHHHCCCCCCCCCEEEEECCCHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCH
EHVSEAAKRRQRDELGTLGSGNHYLELQEVTQIYDVPAADRFRLRVGELVVSIHCGSRGL
HHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCHHHEEEEEEEEEEECCCCCC
GHQIGTEFLKAMVLAAPAHGIDLPDRELACAPIDSALGQSYLGAMRAATNCALANREVIT
CHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
HLVRQVFADVVPDSHLALVYDVSHNTCKQESYTVDGKAKRLYVHRKGATRAFGPGHPGLP
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCCCC
PELRDIGQPVIVGGSMGTASYILVGTEASHQLAFSSACHGAGRAMSRHQASRTWHGRALV
HHHHHCCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DELAAQGVLIRSPSSRGVAEEAPGAYKDVRAVVDAADRAGLARKVARLRPLVCIKG
HHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MDLARLQQASAVEWRIGPHGRMRVPAVIFADEDLVRQMDDKVYEQITHVAALPGIVQAAY
CCHHHHHHCCCEEEEECCCCCEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMPDAHWGYGFPIGGVAAFDADEGGVVSAGGVGFDISCGVRTLHTGLTVADIAPVKQKLA
HCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEECCCHHHHHCCCCHHHHHHHHHHHH
DRLFASIPAGVGSSGKLRLNSVDMDAMLRGGACWAVERGYGSPADLERIEERGCVAGAAP
HHHHHHCCCCCCCCCEEEEECCCHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCH
EHVSEAAKRRQRDELGTLGSGNHYLELQEVTQIYDVPAADRFRLRVGELVVSIHCGSRGL
HHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCHHHEEEEEEEEEEECCCCCC
GHQIGTEFLKAMVLAAPAHGIDLPDRELACAPIDSALGQSYLGAMRAATNCALANREVIT
CHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
HLVRQVFADVVPDSHLALVYDVSHNTCKQESYTVDGKAKRLYVHRKGATRAFGPGHPGLP
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCCCC
PELRDIGQPVIVGGSMGTASYILVGTEASHQLAFSSACHGAGRAMSRHQASRTWHGRALV
HHHHHCCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DELAAQGVLIRSPSSRGVAEEAPGAYKDVRAVVDAADRAGLARKVARLRPLVCIKG
HHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]