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The map label for this gene is fpr [H]

Identifier: 74318376

GI number: 74318376

Start: 2430992

End: 2431738

Strand: Reverse

Name: fpr [H]

Synonym: Tbd_2358

Alternate gene names: 74318376

Gene position: 2431738-2430992 (Counterclockwise)

Preceding gene: 74318377

Following gene: 74318372

Centisome position: 83.57

GC content: 64.39

Gene sequence:

>747_bases
ATGCCCTATAGCGAACAAACCGTACAGTGGGTGCGGCCGTGGTCCGACAAGACGTTCAGCTTCACGGTGACGCGTCCGCA
GGATTTCTCGTTCGCGAACGGCGAGTTCGTCACGATCGGACTCAAGCAGGAAGGCAAGCTCGTGGCGCGTGCCTATTCGA
TCGTCTCGACGGCCGACCGCGACTATCTCGAGTTCCTGAGCATCCATGTCCCGGACGGGCCGCTGACGAGTCAGCTTTCA
CAGATCAAGCCGGGCGACCGGGTCTGGATCAACAACAAGACGACGGGAACGCTGACGCTCGACCACGTGTCGCCGGGGCG
CGTCCTTTACATGCTCGCCACCGGCACCGGGGTCGCGCCCTTCGTGAGCCTCGTGCGCGATCCCGCGATCTTCGCGCGCT
TCGAAACGGTCGTGCTCGTGCATTCGGTTCGGACGGCCGCCGAACTCGCGTATCGCGAGGAACTCGAGGCCATGGACCAG
CCACAACTGCACTACGTGCCGACGGTGACCCGCGAGCCGTTTCCGACGACCGAGCGCGGCAGCGAACTTTTTCGCTCGGG
CCTGCTGTCGCAGCGCCTGGGTTTACCGCCGCCCGACCCCGAGCAGGACCGCGTGATGATCTGCGGCAACCCGCAGATGA
CGCGCGAAATGACGCGCTTTCTCAAGGACACCGGCTGGACGCTGACGACCCCGCGCGGGCTCGGCAATTTCACGACAGAA
GTCGCCTTCGTCCTGCATCACGGCTGA

Upstream 100 bases:

>100_bases
GGCTCAGGCCGCTCGTCTGCATCAAGGGCTGACCGCAGGGCCGGAACTGTCGTCGCGCCCGGGCGTCGAAAAAGCGTCTA
TCCAGCATGGAGCAACCGCG

Downstream 100 bases:

>100_bases
ACAGGAGCCGCGCCTCAGCCGTGCCGATGGTGCTTGTGGTGCCGATGTTTGCCGTGGCCGCGGTCGTAGTGGTGGTGGCG
GTCGCCGCCCTCGCGCCAGT

Product: ferredoxin-NADP reductase

Products: NA

Alternate protein names: FNR; Protein X [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MPYSEQTVQWVRPWSDKTFSFTVTRPQDFSFANGEFVTIGLKQEGKLVARAYSIVSTADRDYLEFLSIHVPDGPLTSQLS
QIKPGDRVWINNKTTGTLTLDHVSPGRVLYMLATGTGVAPFVSLVRDPAIFARFETVVLVHSVRTAAELAYREELEAMDQ
PQLHYVPTVTREPFPTTERGSELFRSGLLSQRLGLPPPDPEQDRVMICGNPQMTREMTRFLKDTGWTLTTPRGLGNFTTE
VAFVLHHG

Sequences:

>Translated_248_residues
MPYSEQTVQWVRPWSDKTFSFTVTRPQDFSFANGEFVTIGLKQEGKLVARAYSIVSTADRDYLEFLSIHVPDGPLTSQLS
QIKPGDRVWINNKTTGTLTLDHVSPGRVLYMLATGTGVAPFVSLVRDPAIFARFETVVLVHSVRTAAELAYREELEAMDQ
PQLHYVPTVTREPFPTTERGSELFRSGLLSQRLGLPPPDPEQDRVMICGNPQMTREMTRFLKDTGWTLTTPRGLGNFTTE
VAFVLHHG
>Mature_247_residues
PYSEQTVQWVRPWSDKTFSFTVTRPQDFSFANGEFVTIGLKQEGKLVARAYSIVSTADRDYLEFLSIHVPDGPLTSQLSQ
IKPGDRVWINNKTTGTLTLDHVSPGRVLYMLATGTGVAPFVSLVRDPAIFARFETVVLVHSVRTAAELAYREELEAMDQP
QLHYVPTVTREPFPTTERGSELFRSGLLSQRLGLPPPDPEQDRVMICGNPQMTREMTRFLKDTGWTLTTPRGLGNFTTEV
AFVLHHG

Specific function: Transports Electrons Between Flavodoxin Or Ferredoxin And NADPH. Involved In The Reductive Activation Of Cobalamin- Independent Methionine Synthase, Pyruvate Formate Lyase And Anaerobic Ribonucleotide Reductase. Also Protects Against Superoxide Radicals

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=219, Percent_Identity=40.1826484018265, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 27858; Mature: 27727

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSEQTVQWVRPWSDKTFSFTVTRPQDFSFANGEFVTIGLKQEGKLVARAYSIVSTADR
CCCCCCHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCH
DYLEFLSIHVPDGPLTSQLSQIKPGDRVWINNKTTGTLTLDHVSPGRVLYMLATGTGVAP
HHHEEEEEECCCCCHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCEEEEEEECCCCHHH
FVSLVRDPAIFARFETVVLVHSVRTAAELAYREELEAMDQPQLHYVPTVTREPFPTTERG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHH
SELFRSGLLSQRLGLPPPDPEQDRVMICGNPQMTREMTRFLKDTGWTLTTPRGLGNFTTE
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCHHHE
VAFVLHHG
EEEEEECC
>Mature Secondary Structure 
PYSEQTVQWVRPWSDKTFSFTVTRPQDFSFANGEFVTIGLKQEGKLVARAYSIVSTADR
CCCCCHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCH
DYLEFLSIHVPDGPLTSQLSQIKPGDRVWINNKTTGTLTLDHVSPGRVLYMLATGTGVAP
HHHEEEEEECCCCCHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCEEEEEEECCCCHHH
FVSLVRDPAIFARFETVVLVHSVRTAAELAYREELEAMDQPQLHYVPTVTREPFPTTERG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHH
SELFRSGLLSQRLGLPPPDPEQDRVMICGNPQMTREMTRFLKDTGWTLTTPRGLGNFTTE
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCHHHE
VAFVLHHG
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7673160; 8034707; 9865948 [H]