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The map label for this gene is gmhB [H]

Identifier: 74318364

GI number: 74318364

Start: 2419510

End: 2420052

Strand: Reverse

Name: gmhB [H]

Synonym: Tbd_2346

Alternate gene names: 74318364

Gene position: 2420052-2419510 (Counterclockwise)

Preceding gene: 74318365

Following gene: 74318363

Centisome position: 83.17

GC content: 66.3

Gene sequence:

>543_bases
ATGAAACTCATCATTCTCGACCGCGACGGCGTCATCAACTTCGATTCCGACCACTTCATCAAGTCGCCGGACGAATGGAA
GCCGATTCCCGGCAGCCTCGAAGCGATCGGACGGCTGACGCGAGAAGGTTGGCGCGTCGTCGTCGCGACCAACCAGTCGG
GACTTGCGCGCGGCCTGTTCGAGATGGCCACCCTGAACGCCATCCACGCCAAGATGCACCGTGCGGTCGCCCAGGCAGGC
GGGCGCATCGAGGCGGTTTTCTATTGCCCGCACGCCGCCGACATGAACTGCGGCTGTCGCAAGCCCAAACCCGGCCTCTT
TACCGAAATCGCGGCGCGCTACAGCCGCGACCTGAATGACGTGCCTGCAGTCGGCGATTCGCTGCGCGACCTGCTGGCGG
CCGCGACGGTCGGCGCGCGCCCGCTGCTGGTGCGCACCGGCAAAGGCGAACGCACGCTCGCGGCCGGCGGCATGCCGGAC
AACACGCCGGTTTATTCCGACCTCAGCGAGGCCGTCGACCACCTGCTCAAGGCCGTCGCATGA

Upstream 100 bases:

>100_bases
CCCGGCGCTCAGGGCCAACCGGCTCGCGCTGCTGAATCAGCTGCACCGGACGATGAACCGCGTGGCTGACATCTCCCGGC
TCGCCGCCTAAACTTCCGCT

Downstream 100 bases:

>100_bases
GCCTCGTCCGCTCGCTGGTCTTCGCGGTCCTGCAGACCGCGCTGACAATCCTTTTCAGTCTGGTCGCCTTGCTGTCCTTC
CCGTTTTCGGCGCACGCGCG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKLIILDRDGVINFDSDHFIKSPDEWKPIPGSLEAIGRLTREGWRVVVATNQSGLARGLFEMATLNAIHAKMHRAVAQAG
GRIEAVFYCPHAADMNCGCRKPKPGLFTEIAARYSRDLNDVPAVGDSLRDLLAAATVGARPLLVRTGKGERTLAAGGMPD
NTPVYSDLSEAVDHLLKAVA

Sequences:

>Translated_180_residues
MKLIILDRDGVINFDSDHFIKSPDEWKPIPGSLEAIGRLTREGWRVVVATNQSGLARGLFEMATLNAIHAKMHRAVAQAG
GRIEAVFYCPHAADMNCGCRKPKPGLFTEIAARYSRDLNDVPAVGDSLRDLLAAATVGARPLLVRTGKGERTLAAGGMPD
NTPVYSDLSEAVDHLLKAVA
>Mature_180_residues
MKLIILDRDGVINFDSDHFIKSPDEWKPIPGSLEAIGRLTREGWRVVVATNQSGLARGLFEMATLNAIHAKMHRAVAQAG
GRIEAVFYCPHAADMNCGCRKPKPGLFTEIAARYSRDLNDVPAVGDSLRDLLAAATVGARPLLVRTGKGERTLAAGGMPD
NTPVYSDLSEAVDHLLKAVA

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=154, Percent_Identity=37.012987012987, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI87082027, Length=143, Percent_Identity=30.0699300699301, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 19389; Mature: 19389

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIILDRDGVINFDSDHFIKSPDEWKPIPGSLEAIGRLTREGWRVVVATNQSGLARGLF
CEEEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHH
EMATLNAIHAKMHRAVAQAGGRIEAVFYCPHAADMNCGCRKPKPGLFTEIAARYSRDLND
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
VPAVGDSLRDLLAAATVGARPLLVRTGKGERTLAAGGMPDNTPVYSDLSEAVDHLLKAVA
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLIILDRDGVINFDSDHFIKSPDEWKPIPGSLEAIGRLTREGWRVVVATNQSGLARGLF
CEEEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHH
EMATLNAIHAKMHRAVAQAGGRIEAVFYCPHAADMNCGCRKPKPGLFTEIAARYSRDLND
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
VPAVGDSLRDLLAAATVGARPLLVRTGKGERTLAAGGMPDNTPVYSDLSEAVDHLLKAVA
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]