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The map label for this gene is dsbC [H]

Identifier: 74318349

GI number: 74318349

Start: 2404727

End: 2405437

Strand: Reverse

Name: dsbC [H]

Synonym: Tbd_2331

Alternate gene names: 74318349

Gene position: 2405437-2404727 (Counterclockwise)

Preceding gene: 74318350

Following gene: 74318348

Centisome position: 82.67

GC content: 63.15

Gene sequence:

>711_bases
ATGAAATTCACTTCCCTGGCGCTGGCTGCAAGCCTGATGTTCGCCGCAGCCGCCCACGCCGACGAGAAGCTGATCCGCAA
GACCCTGGCACAGCAGTTCCCGGGTGCGAAGGTCAGTTCGGTCAAGCCGACGCCTTACAGCGGCCTGTTCGAGGTCTACC
TCGACGGCCAGCTCGTCTACGTCGACGCGAAGGCGAAATACGTCTTCGCGGGCGACGTGATCGACCTGAAGAATCGCACG
AACCTGACGCAGGCGCGACTCAACCAGTTGCAGGCCGTGAGTTGGGACGTGTTTCCGCTCAACAACGCGCTGAAGACCGT
GAAAGGCAACGGCGCGCGCAAGCTGGTGCTGTTCTCTGACGTCGATTGCCCGTATTGCCGCAAGTTCGAGGCTGAACTCA
CCAAGGTCGACAACATCACCGTCTACACTTTCCTCTACCCGATCGCCGGGCTGCACCCGAAGGCCGTCCAGACGTCGAAG
CAGATCTGGTGTGCGCCCGACCGCAACAAGGCCTGGGACGCCTACATCACGCGCGGCACCGTGCCCGACAACGACGGCAA
GTGCGCCAACCCGGTCGACGCCACGATCGCCCTCGGCAACCGGTTGAAAGTAAACGGCACGCCAACGCTGTTCTTCGCCA
ACGGCGTGCGCGTGCCCGGCATGGTGCCCGCCGCGCAACTCGAGCGACTGCTTGCCGCCAACGCGAAGTGA

Upstream 100 bases:

>100_bases
AACGCCGGGATGGACCTCGTCGACCACCTGCCGCCACTCAAGGCGGCGCTGATACGTGAAGCAATGTCCTGATCTTTTTT
CGATTTCTTTGGAGCGACGC

Downstream 100 bases:

>100_bases
GCACCGAGTTCTGGAACGCGCGCTACGCGACCGACGAATACGTCTTCGGCACCGCGCCAAACGTGTTTCTGGCGAGCCAG
AAGGCCTTGGTGCATCCGGG

Product: thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKFTSLALAASLMFAAAAHADEKLIRKTLAQQFPGAKVSSVKPTPYSGLFEVYLDGQLVYVDAKAKYVFAGDVIDLKNRT
NLTQARLNQLQAVSWDVFPLNNALKTVKGNGARKLVLFSDVDCPYCRKFEAELTKVDNITVYTFLYPIAGLHPKAVQTSK
QIWCAPDRNKAWDAYITRGTVPDNDGKCANPVDATIALGNRLKVNGTPTLFFANGVRVPGMVPAAQLERLLAANAK

Sequences:

>Translated_236_residues
MKFTSLALAASLMFAAAAHADEKLIRKTLAQQFPGAKVSSVKPTPYSGLFEVYLDGQLVYVDAKAKYVFAGDVIDLKNRT
NLTQARLNQLQAVSWDVFPLNNALKTVKGNGARKLVLFSDVDCPYCRKFEAELTKVDNITVYTFLYPIAGLHPKAVQTSK
QIWCAPDRNKAWDAYITRGTVPDNDGKCANPVDATIALGNRLKVNGTPTLFFANGVRVPGMVPAAQLERLLAANAK
>Mature_236_residues
MKFTSLALAASLMFAAAAHADEKLIRKTLAQQFPGAKVSSVKPTPYSGLFEVYLDGQLVYVDAKAKYVFAGDVIDLKNRT
NLTQARLNQLQAVSWDVFPLNNALKTVKGNGARKLVLFSDVDCPYCRKFEAELTKVDNITVYTFLYPIAGLHPKAVQTSK
QIWCAPDRNKAWDAYITRGTVPDNDGKCANPVDATIALGNRLKVNGTPTLFFANGVRVPGMVPAAQLERLLAANAK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=242, Percent_Identity=30.1652892561983, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 25781; Mature: 25781

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTSLALAASLMFAAAAHADEKLIRKTLAQQFPGAKVSSVKPTPYSGLFEVYLDGQLVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEE
VDAKAKYVFAGDVIDLKNRTNLTQARLNQLQAVSWDVFPLNNALKTVKGNGARKLVLFSD
EECCEEEEEECCEEECCCCCCHHHHHHHHHHHEEEEEEECCCHHHHHCCCCCEEEEEEEC
VDCPYCRKFEAELTKVDNITVYTFLYPIAGLHPKAVQTSKQIWCAPDRNKAWDAYITRGT
CCCHHHHHHHHHHHHCCCEEEEEEEHHHCCCCCHHHCCCCEEEECCCCCCCCEEEEEECC
VPDNDGKCANPVDATIALGNRLKVNGTPTLFFANGVRVPGMVPAAQLERLLAANAK
CCCCCCCCCCCCCEEEEECCEEEECCCCEEEEECCEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKFTSLALAASLMFAAAAHADEKLIRKTLAQQFPGAKVSSVKPTPYSGLFEVYLDGQLVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEE
VDAKAKYVFAGDVIDLKNRTNLTQARLNQLQAVSWDVFPLNNALKTVKGNGARKLVLFSD
EECCEEEEEECCEEECCCCCCHHHHHHHHHHHEEEEEEECCCHHHHHCCCCCEEEEEEEC
VDCPYCRKFEAELTKVDNITVYTFLYPIAGLHPKAVQTSKQIWCAPDRNKAWDAYITRGT
CCCHHHHHHHHHHHHCCCEEEEEEEHHHCCCCCHHHCCCCEEEECCCCCCCCEEEEEECC
VPDNDGKCANPVDATIALGNRLKVNGTPTLFFANGVRVPGMVPAAQLERLLAANAK
CCCCCCCCCCCCCEEEEECCEEEECCCCEEEEECCEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]