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The map label for this gene is visC [H]

Identifier: 74318350

GI number: 74318350

Start: 2405466

End: 2406623

Strand: Reverse

Name: visC [H]

Synonym: Tbd_2332

Alternate gene names: 74318350

Gene position: 2406623-2405466 (Counterclockwise)

Preceding gene: 74318351

Following gene: 74318349

Centisome position: 82.71

GC content: 71.16

Gene sequence:

>1158_bases
GTGAGCCGCGCCCGCCATCAGGTAGTGGTCGTCGGCGCTGGCCTCGTCGGCGCCGCAACGGCACTCGCGCTCGCGCGACA
AGGCCTGCGCGTGGCCTTGATCGAGCGGCGTCCGCCCGACGTTCCCGATGCGACCTGGGACACCCGGATCTACGCCATCA
GCCCGGCGAGCCAGCGCTTTCTCGAACGGCTCGGCGCCTGGCAGAAAATGGACGCGGCGCGCATTCAGCCGATTTACCGC
ATGGAGGTGGCGGGCGACGGCCACGGCGCGGTGCGGCTCGACGCTTACGAAGCCGGCGTCTCGCATCTCGCCTCGATCGT
CGAGAGCGGCCGCCTGCAGGACGCGCTGTGGCGCACGATCGAGGCCGACGGTAGCGTCGCCGTGCACTGCCCGGCTGCGA
TCGACGCGCTCGACCGCGGCGAAGATTCGACCCGCGTGACGCTCGCCGACGGCACCGTTCTCGAAGCCGATCTCGTCGTC
GGCGCCGACGGCGCGGCGTCCCGCATCCGTGACTGGGCGGGCCTTGCCGCGGAGGTCACGCCCTATGAGCGAAGCGGGGT
CGTTGCCAATTTCGATTGCGAACGACCCCATCACGGCACGGCCTTCCAGTGGTTTTCGGGCAGCGACGTCCTTGCCTGGC
TACCGCTGCCCGGGAACCGCGTGTCGATCGTCTGGTCAACGGAGATGGCCTCCGCCGCGGCGCTGCTGGCGCTGCCTGCG
TCCGAACTGGCGGAAAAGGTCCGCGCGGCGGGCGGTGACCGGCTCGGCGCCCTGCGTCTGCTGACGCCGCCCGCGGCTTT
TCCCTTGCGACTTATCCGCGTCGAATCCCCGATCGCACCCGGCGTCGCGCTGGTCGGCGATGCCGCCCACGGCGTACACC
CGCTTGCCGGACAAGGTGTGAACCTCGGCTTCGGTGACGCCGAGGCGCTCGTCGCCGTGCTCGCGCAGCATCGCCGTGCC
AGCCCCGGTGATCCCGCGCTGCTGCGCCGCTACGCGCGCGCGCGGGCCGAACCGGTCGCGCGCATACAGGGCGTCACGCA
CGGGCTGCACCATCTCTTCGCGGCACCGCGCGCCCAGTGGCTGCGCAACGCCGGGATGGACCTCGTCGACCACCTGCCGC
CACTCAAGGCGGCGCTGATACGTGAAGCAATGTCCTGA

Upstream 100 bases:

>100_bases
CGGTGCTGCGTCACGCCCGCGGGCTCGGCTTGCTGGCGCTCGAGGCGCTGCCGCCGCTGAAGGCCTTCGTCGCGCGGCGC
ATGATGTTCGGGGCGCGCGG

Downstream 100 bases:

>100_bases
TCTTTTTTCGATTTCTTTGGAGCGACGCATGAAATTCACTTCCCTGGCGCTGGCTGCAAGCCTGATGTTCGCCGCAGCCG
CCCACGCCGACGAGAAGCTG

Product: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSRARHQVVVVGAGLVGAATALALARQGLRVALIERRPPDVPDATWDTRIYAISPASQRFLERLGAWQKMDAARIQPIYR
MEVAGDGHGAVRLDAYEAGVSHLASIVESGRLQDALWRTIEADGSVAVHCPAAIDALDRGEDSTRVTLADGTVLEADLVV
GADGAASRIRDWAGLAAEVTPYERSGVVANFDCERPHHGTAFQWFSGSDVLAWLPLPGNRVSIVWSTEMASAAALLALPA
SELAEKVRAAGGDRLGALRLLTPPAAFPLRLIRVESPIAPGVALVGDAAHGVHPLAGQGVNLGFGDAEALVAVLAQHRRA
SPGDPALLRRYARARAEPVARIQGVTHGLHHLFAAPRAQWLRNAGMDLVDHLPPLKAALIREAMS

Sequences:

>Translated_385_residues
MSRARHQVVVVGAGLVGAATALALARQGLRVALIERRPPDVPDATWDTRIYAISPASQRFLERLGAWQKMDAARIQPIYR
MEVAGDGHGAVRLDAYEAGVSHLASIVESGRLQDALWRTIEADGSVAVHCPAAIDALDRGEDSTRVTLADGTVLEADLVV
GADGAASRIRDWAGLAAEVTPYERSGVVANFDCERPHHGTAFQWFSGSDVLAWLPLPGNRVSIVWSTEMASAAALLALPA
SELAEKVRAAGGDRLGALRLLTPPAAFPLRLIRVESPIAPGVALVGDAAHGVHPLAGQGVNLGFGDAEALVAVLAQHRRA
SPGDPALLRRYARARAEPVARIQGVTHGLHHLFAAPRAQWLRNAGMDLVDHLPPLKAALIREAMS
>Mature_384_residues
SRARHQVVVVGAGLVGAATALALARQGLRVALIERRPPDVPDATWDTRIYAISPASQRFLERLGAWQKMDAARIQPIYRM
EVAGDGHGAVRLDAYEAGVSHLASIVESGRLQDALWRTIEADGSVAVHCPAAIDALDRGEDSTRVTLADGTVLEADLVVG
ADGAASRIRDWAGLAAEVTPYERSGVVANFDCERPHHGTAFQWFSGSDVLAWLPLPGNRVSIVWSTEMASAAALLALPAS
ELAEKVRAAGGDRLGALRLLTPPAAFPLRLIRVESPIAPGVALVGDAAHGVHPLAGQGVNLGFGDAEALVAVLAQHRRAS
PGDPALLRRYARARAEPVARIQGVTHGLHHLFAAPRAQWLRNAGMDLVDHLPPLKAALIREAMS

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=407, Percent_Identity=28.7469287469287, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI32967307, Length=393, Percent_Identity=28.498727735369, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1789273, Length=385, Percent_Identity=38.4415584415584, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI1786883, Length=388, Percent_Identity=35.5670103092784, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1789274, Length=387, Percent_Identity=32.0413436692506, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25146631, Length=431, Percent_Identity=27.6102088167053, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI19920760, Length=422, Percent_Identity=32.2274881516588, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40812; Mature: 40681

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRARHQVVVVGAGLVGAATALALARQGLRVALIERRPPDVPDATWDTRIYAISPASQRF
CCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCHHHHH
LERLGAWQKMDAARIQPIYRMEVAGDGHGAVRLDAYEAGVSHLASIVESGRLQDALWRTI
HHHHCCHHHCCHHHCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHH
EADGSVAVHCPAAIDALDRGEDSTRVTLADGTVLEADLVVGADGAASRIRDWAGLAAEVT
CCCCCEEEECCHHHHHHHCCCCCCEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCEECC
PYERSGVVANFDCERPHHGTAFQWFSGSDVLAWLPLPGNRVSIVWSTEMASAAALLALPA
CCCCCCEEEECCCCCCCCCCEEEEECCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCH
SELAEKVRAAGGDRLGALRLLTPPAAFPLRLIRVESPIAPGVALVGDAAHGVHPLAGQGV
HHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
NLGFGDAEALVAVLAQHRRASPGDPALLRRYARARAEPVARIQGVTHGLHHLFAAPRAQW
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHH
LRNAGMDLVDHLPPLKAALIREAMS
HHHCCCHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SRARHQVVVVGAGLVGAATALALARQGLRVALIERRPPDVPDATWDTRIYAISPASQRF
CCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCHHHHH
LERLGAWQKMDAARIQPIYRMEVAGDGHGAVRLDAYEAGVSHLASIVESGRLQDALWRTI
HHHHCCHHHCCHHHCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHH
EADGSVAVHCPAAIDALDRGEDSTRVTLADGTVLEADLVVGADGAASRIRDWAGLAAEVT
CCCCCEEEECCHHHHHHHCCCCCCEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCEECC
PYERSGVVANFDCERPHHGTAFQWFSGSDVLAWLPLPGNRVSIVWSTEMASAAALLALPA
CCCCCCEEEECCCCCCCCCCEEEEECCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCH
SELAEKVRAAGGDRLGALRLLTPPAAFPLRLIRVESPIAPGVALVGDAAHGVHPLAGQGV
HHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
NLGFGDAEALVAVLAQHRRASPGDPALLRRYARARAEPVARIQGVTHGLHHLFAAPRAQW
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHH
LRNAGMDLVDHLPPLKAALIREAMS
HHHCCCHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]