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The map label for this gene is mod [H]

Identifier: 74318294

GI number: 74318294

Start: 2349228

End: 2350907

Strand: Reverse

Name: mod [H]

Synonym: Tbd_2276

Alternate gene names: 74318294

Gene position: 2350907-2349228 (Counterclockwise)

Preceding gene: 74318295

Following gene: 74318293

Centisome position: 80.79

GC content: 60.3

Gene sequence:

>1680_bases
TTGCCAGGCTGTGGCTCGGGGCCTGATGGCTACCGCGCAAGCCAGAAACTGACCGCTACAACCAACAACATGCCAACACT
GCACTGGGTAGGAAAAGACAAGGTGATCAACCACCACCACGATGTGCCGTTTCGCGTGCTCCAGAAGGTTTCGACCTTTA
CCGCGCCCGAAGGCACGCCCGCGAATACCACCGACAACCGCATCATCCACGGCGACAACCTCGAAGCCCTGAAGAGCCTG
CTACCCGAGTTCGAGGGCCGCGTGAAGTGCATCTACATCGATCCGCCGTACAACACCGGCAACGAGGGGTGGGTCTACAA
CGACGCCGTCAACGATCCGAAGATCAAGCGCTGGCTCGGCCAAGTGGTGGGCAAGGAAGGCGAGGACCTGTCGCGCCACG
ACAAGTGGCTGTGCATGATGTATCCGCGTCTGAAACTCCTGCATCGCTTGCTGCATGACGACGGGTCAATTTGGGTTTCG
ATTGACGACAACGCCTCCGGCCTGCTGCGTCCATTGTTGGACGAAATTTTCGGGGGTGCCAACTTCGTCGCGACCGTCAT
CTGGGAAAAGGCAGACTCCCCCAGGAACTCGGCGCGCCAGTTCTCGACCGATCACGACTACATCCTCGTCTACTCCAAGA
AGCCAGGCTGGACGCCTGCTCGCCTGCCACGCAACGAAGAATCCGATGCGATCTATCAAAATCAGGATGATGACGAGCGC
GGCCCTTGGATACCAGGCGATCCCTTTGCCAACAAGCCGTATTCAAAGGGCTTGTACACGATCACGGGGCCTACCGGCCG
GGAGTTTTCGCCTCCGGCTGGTCGCTACTGGCGTGTGTCAGAGGAAAAGCTGAGGGAGTTGGATGACGACGGCCGGATTT
GGTGGGGTCCGACCGGCGAAGCTAGGCCCAGCATCAAACGCTATTTGAACGAGGTGGCCGACCTTGTGCCCCGCACACTC
TGGACCAAGGAGGCCGTAGGTAGCAATCGTTCGTCCAAAAACGAACAGCGCGCGATCTTTGCTGGCACTGCGTCGTTTGA
CACGCCGAAGCCCAGCGCATTGATCGAGCGAGTTATCCAGATAGCAGCGTCGTCCAGCGACATCGTGCTGGATTCTTTCG
CTGGCTCCGGAACAACTGGGCACGCAGTGATGAAGCTGAACGCTCAGGACTCAGGGGCGCGGCGCTTCGTGATGATCGAG
ACCGAAAGCTATGCGGATACGTTGACCGCCGAGCGGATCAGACGGGTGATGACTGGCTACGGCGAAGGCACGAAGGCAAT
GCAAGGCCTCGGCGGCGGCTTCGACTACTACATCGTCGGCGAGCCGATGTTTCTACCCGACGACAACCTCAATGAAGCCG
CCGGCACCGAGGCCATCCGGGGCTACGTGGCCTACAGCGAGGGCATCCCCACTGCCGACCAGACCACAACCGACAACCCG
CACAGCCCTTATCTGCTGGGCCTGAACCGGGAAACGGCCTGGCTCTTCCACTACGAGCCGGACCGTGCGACCAGCCTGGA
CATGGACTTTCTGGCCGGCCTGCGCTTTGGCGGCGATACCGGCGCCGGCAAGCCCGACACTGTGATCGTCTACGCCGACC
GTTGCCTGCTGTCGAAGGACTTCATGATCCGGCACGGCATCGTCTTCAAGAAGATTCCCCGCGACATCACCCGCTTCTGA

Upstream 100 bases:

>100_bases
TACCTGCACGGCGATTACCTGATTCTGTATATCGCATCGGAAACCGATGCCACCGTTTACCTGCTGTCCGTCCGGCATCA
CCGCCAGCTTTCGTTCGACT

Downstream 100 bases:

>100_bases
CCGAAAAGAACAACAACGAGAGCAGACACACCATGGAACTCAAGGATTATCAGGCCCGCGTGCTGGCCGATCTGGCGGGC
TACCTCGACGTGCTGGACGG

Product: adenine specific DNA methylase

Products: NA

Alternate protein names: M.StyLTI; StyLTI methyltransferase [H]

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MPGCGSGPDGYRASQKLTATTNNMPTLHWVGKDKVINHHHDVPFRVLQKVSTFTAPEGTPANTTDNRIIHGDNLEALKSL
LPEFEGRVKCIYIDPPYNTGNEGWVYNDAVNDPKIKRWLGQVVGKEGEDLSRHDKWLCMMYPRLKLLHRLLHDDGSIWVS
IDDNASGLLRPLLDEIFGGANFVATVIWEKADSPRNSARQFSTDHDYILVYSKKPGWTPARLPRNEESDAIYQNQDDDER
GPWIPGDPFANKPYSKGLYTITGPTGREFSPPAGRYWRVSEEKLRELDDDGRIWWGPTGEARPSIKRYLNEVADLVPRTL
WTKEAVGSNRSSKNEQRAIFAGTASFDTPKPSALIERVIQIAASSSDIVLDSFAGSGTTGHAVMKLNAQDSGARRFVMIE
TESYADTLTAERIRRVMTGYGEGTKAMQGLGGGFDYYIVGEPMFLPDDNLNEAAGTEAIRGYVAYSEGIPTADQTTTDNP
HSPYLLGLNRETAWLFHYEPDRATSLDMDFLAGLRFGGDTGAGKPDTVIVYADRCLLSKDFMIRHGIVFKKIPRDITRF

Sequences:

>Translated_559_residues
MPGCGSGPDGYRASQKLTATTNNMPTLHWVGKDKVINHHHDVPFRVLQKVSTFTAPEGTPANTTDNRIIHGDNLEALKSL
LPEFEGRVKCIYIDPPYNTGNEGWVYNDAVNDPKIKRWLGQVVGKEGEDLSRHDKWLCMMYPRLKLLHRLLHDDGSIWVS
IDDNASGLLRPLLDEIFGGANFVATVIWEKADSPRNSARQFSTDHDYILVYSKKPGWTPARLPRNEESDAIYQNQDDDER
GPWIPGDPFANKPYSKGLYTITGPTGREFSPPAGRYWRVSEEKLRELDDDGRIWWGPTGEARPSIKRYLNEVADLVPRTL
WTKEAVGSNRSSKNEQRAIFAGTASFDTPKPSALIERVIQIAASSSDIVLDSFAGSGTTGHAVMKLNAQDSGARRFVMIE
TESYADTLTAERIRRVMTGYGEGTKAMQGLGGGFDYYIVGEPMFLPDDNLNEAAGTEAIRGYVAYSEGIPTADQTTTDNP
HSPYLLGLNRETAWLFHYEPDRATSLDMDFLAGLRFGGDTGAGKPDTVIVYADRCLLSKDFMIRHGIVFKKIPRDITRF
>Mature_558_residues
PGCGSGPDGYRASQKLTATTNNMPTLHWVGKDKVINHHHDVPFRVLQKVSTFTAPEGTPANTTDNRIIHGDNLEALKSLL
PEFEGRVKCIYIDPPYNTGNEGWVYNDAVNDPKIKRWLGQVVGKEGEDLSRHDKWLCMMYPRLKLLHRLLHDDGSIWVSI
DDNASGLLRPLLDEIFGGANFVATVIWEKADSPRNSARQFSTDHDYILVYSKKPGWTPARLPRNEESDAIYQNQDDDERG
PWIPGDPFANKPYSKGLYTITGPTGREFSPPAGRYWRVSEEKLRELDDDGRIWWGPTGEARPSIKRYLNEVADLVPRTLW
TKEAVGSNRSSKNEQRAIFAGTASFDTPKPSALIERVIQIAASSSDIVLDSFAGSGTTGHAVMKLNAQDSGARRFVMIET
ESYADTLTAERIRRVMTGYGEGTKAMQGLGGGFDYYIVGEPMFLPDDNLNEAAGTEAIRGYVAYSEGIPTADQTTTDNPH
SPYLLGLNRETAWLFHYEPDRATSLDMDFLAGLRFGGDTGAGKPDTVIVYADRCLLSKDFMIRHGIVFKKIPRDITRF

Specific function: Binds the system-specific DNA recognition site 5'-CAGAG- 3'. Necessary for restriction and for methylation of A-4 [H]

COG id: COG2189

COG function: function code L; Adenine specific DNA methylase Mod

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002295
- InterPro:   IPR002941
- InterPro:   IPR002052 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 62359; Mature: 62227

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGCGSGPDGYRASQKLTATTNNMPTLHWVGKDKVINHHHDVPFRVLQKVSTFTAPEGTP
CCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCEECCCCCCHHHHHHHHHHHCCCCCCC
ANTTDNRIIHGDNLEALKSLLPEFEGRVKCIYIDPPYNTGNEGWVYNDAVNDPKIKRWLG
CCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHH
QVVGKEGEDLSRHDKWLCMMYPRLKLLHRLLHDDGSIWVSIDDNASGLLRPLLDEIFGGA
HHHCCCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCC
NFVATVIWEKADSPRNSARQFSTDHDYILVYSKKPGWTPARLPRNEESDAIYQNQDDDER
CEEEEEEECCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPWIPGDPFANKPYSKGLYTITGPTGREFSPPAGRYWRVSEEKLRELDDDGRIWWGPTGE
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEECCCCC
ARPSIKRYLNEVADLVPRTLWTKEAVGSNRSSKNEQRAIFAGTASFDTPKPSALIERVIQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
IAASSSDIVLDSFAGSGTTGHAVMKLNAQDSGARRFVMIETESYADTLTAERIRRVMTGY
HHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC
GEGTKAMQGLGGGFDYYIVGEPMFLPDDNLNEAAGTEAIRGYVAYSEGIPTADQTTTDNP
CCCHHHHHHCCCCCEEEEECCEEECCCCCCCHHHCHHHHHEEEEECCCCCCCCCCCCCCC
HSPYLLGLNRETAWLFHYEPDRATSLDMDFLAGLRFGGDTGAGKPDTVIVYADRCLLSKD
CCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCC
FMIRHGIVFKKIPRDITRF
HHHHCCHHHHHCCHHHHCC
>Mature Secondary Structure 
PGCGSGPDGYRASQKLTATTNNMPTLHWVGKDKVINHHHDVPFRVLQKVSTFTAPEGTP
CCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCEECCCCCCHHHHHHHHHHHCCCCCCC
ANTTDNRIIHGDNLEALKSLLPEFEGRVKCIYIDPPYNTGNEGWVYNDAVNDPKIKRWLG
CCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHH
QVVGKEGEDLSRHDKWLCMMYPRLKLLHRLLHDDGSIWVSIDDNASGLLRPLLDEIFGGA
HHHCCCCCCHHHHCCEEEEHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCC
NFVATVIWEKADSPRNSARQFSTDHDYILVYSKKPGWTPARLPRNEESDAIYQNQDDDER
CEEEEEEECCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPWIPGDPFANKPYSKGLYTITGPTGREFSPPAGRYWRVSEEKLRELDDDGRIWWGPTGE
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEECCCCC
ARPSIKRYLNEVADLVPRTLWTKEAVGSNRSSKNEQRAIFAGTASFDTPKPSALIERVIQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
IAASSSDIVLDSFAGSGTTGHAVMKLNAQDSGARRFVMIETESYADTLTAERIRRVMTGY
HHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC
GEGTKAMQGLGGGFDYYIVGEPMFLPDDNLNEAAGTEAIRGYVAYSEGIPTADQTTTDNP
CCCHHHHHHCCCCCEEEEECCEEECCCCCCCHHHCHHHHHEEEEECCCCCCCCCCCCCCC
HSPYLLGLNRETAWLFHYEPDRATSLDMDFLAGLRFGGDTGAGKPDTVIVYADRCLLSKD
CCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCC
FMIRHGIVFKKIPRDITRF
HHHHCCHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8387444; 11677609 [H]