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The map label for this gene is hmrR2 [H]

Identifier: 74318285

GI number: 74318285

Start: 2339159

End: 2339557

Strand: Direct

Name: hmrR2 [H]

Synonym: Tbd_2267

Alternate gene names: 74318285

Gene position: 2339159-2339557 (Clockwise)

Preceding gene: 74318284

Following gene: 74318287

Centisome position: 80.39

GC content: 71.93

Gene sequence:

>399_bases
ATGAACATCGGCGAGGCCGCCGCCGCGAGTGGCATATCGGCGAAGATGATCCGGCACTACGAGCGCATCGGGCTCGTGCG
CGAGAGCGGCCGTACGCCGGCCGGATACCGGCAATACGAGGCGCGCGACGTCCACCTGCTGCGCTTCGTGCGCCGCGCGC
GCGACCTCGGCTTCTCGCTCGAGCAGATCCGGCAGTTGTTGTCGCTGTGGGAGGACCCGGCGCGCGCGAGCGCGGACGTC
AAGCGGCTGGCCGAAGCGCACATCGCGGAACTCGACGCGCGCATCGCAGCGCTGAGCGAGATGCGCGCGACGCTCGTCAC
GCTCGCCCGCGACTGCCGCGGCGACCACCGTCCCGATTGCCCGATCCTCGCCGACCTCGCGTCCCCGCGCGCGGACTGA

Upstream 100 bases:

>100_bases
TGAGCCCGGTCATTGCGGGCGCGGCGATGGCGTTCTCGAGCGTGAGCGTCGTCACCAACGCGCTGACGCTGAAACGCTGG
CGCCCGGCCGAGGACAGGCG

Downstream 100 bases:

>100_bases
GCTCAATTCCGCCCCTCCCAGTCGTACACGACCTCGATCAGCACGCGAGAACGAACCGGGCGACCCTGTCTTTGCGCCGG
CGCGAAGCGCGCCTCGCGAA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MNIGEAAAASGISAKMIRHYERIGLVRESGRTPAGYRQYEARDVHLLRFVRRARDLGFSLEQIRQLLSLWEDPARASADV
KRLAEAHIAELDARIAALSEMRATLVTLARDCRGDHRPDCPILADLASPRAD

Sequences:

>Translated_132_residues
MNIGEAAAASGISAKMIRHYERIGLVRESGRTPAGYRQYEARDVHLLRFVRRARDLGFSLEQIRQLLSLWEDPARASADV
KRLAEAHIAELDARIAALSEMRATLVTLARDCRGDHRPDCPILADLASPRAD
>Mature_132_residues
MNIGEAAAASGISAKMIRHYERIGLVRESGRTPAGYRQYEARDVHLLRFVRRARDLGFSLEQIRQLLSLWEDPARASADV
KRLAEAHIAELDARIAALSEMRATLVTLARDCRGDHRPDCPILADLASPRAD

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=42.5196850393701, Blast_Score=108, Evalue=9e-26,
Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=37.7952755905512, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14719; Mature: 14719

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGEAAAASGISAKMIRHYERIGLVRESGRTPAGYRQYEARDVHLLRFVRRARDLGFSL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
EQIRQLLSLWEDPARASADVKRLAEAHIAELDARIAALSEMRATLVTLARDCRGDHRPDC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILADLASPRAD
CHHHHCCCCCCC
>Mature Secondary Structure
MNIGEAAAASGISAKMIRHYERIGLVRESGRTPAGYRQYEARDVHLLRFVRRARDLGFSL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
EQIRQLLSLWEDPARASADVKRLAEAHIAELDARIAALSEMRATLVTLARDCRGDHRPDC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILADLASPRAD
CHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]