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The map label for this gene is 74318243

Identifier: 74318243

GI number: 74318243

Start: 2304501

End: 2305769

Strand: Reverse

Name: 74318243

Synonym: Tbd_2225

Alternate gene names: NA

Gene position: 2305769-2304501 (Counterclockwise)

Preceding gene: 74318244

Following gene: 74318242

Centisome position: 79.24

GC content: 63.2

Gene sequence:

>1269_bases
ATGGCACACATCGTAATACTCGGCGCCGGCGTCGGCGGCATGACCATGGCGTATGAAATGCGCGAGTCGGCACGGGCCGA
GGACAAGGTCACCGTCATTTCCAACAATTCGTACTTCCAGTTCACGCCGTCCAACCCCTGGGTGGGGGTGAACTGGCGCA
AGCGTGACGACGTCACGCTCGAGGCCGCGCCTTACCTCAACAAGAAAAACATCGACTTCATTCCGGTCGGCGCCGCGCGC
GTGCATCCCGACAGGAACCAGATCGACCTCACCGACGGCAGGACCGTCGACTATGACTTCCTCGTCATCGCGACGGGGCC
CAAGCTCGCGTTCGACGAAGTCCCGGGCCTCGGCCCCGAGGGTTACACCCAGTCGGTATGCACGGTCGACCATGCCCAGG
CCGCGGGCCGCGCGTGGGACGATTTTGTGAAGAACCCGGGGCCGATCGTGGTCGGCGCGGTGCAGGGGGCTTCCTGCTAC
GGCCCGGCGTACGAGTACGCGATGATCATGGACACCGACCTGCGCAAGCGCAAGATTCGTGACCGCGTGCCGATGACCTA
CGTCACGGCCGAGCCGTATATCGGCCATCTGGGACTGGGCGGCGTCGGCGATTCCAAGGGCATGCTCGAATCGGTCCTCC
GCGAGCGCCACATCAAGTGGATCTGCAACGCCAAGGTCACCAAGGTCGAGGCTGGCAAGATGTTCGTCGCCGAGCACAAC
GACAAGGGCGAAGTGATCAAGGAGCACGAACTGCCGTTCGGCTACTCGATGATGCTGCCGGCGTTCAAGGGCATCGATGC
TGTGTTCGGCATCGAGGGGCTGACCAATCCGCGCGGCTTCATCACGATCGACCCCTACCAGCGCAACGCGAAGTACCCGA
ACGTCTACTCCGTCGGCGTGTGCGTCGCGATCCCACCCGTCGAGGTCACTCCCGTGCCGACCGGCACGCCGAAGACCGGC
TACATGATCGAATCGATGGTGACGGCGACCGCGCACAACATCCGCGCCGTGCTCGACGGCCGCGAGCCTGCCGAGAAGGC
GACCTGGAACGCGATCTGCCTCGCCGACTTCGGCGACACCGGCGCCGCCTTCGTGGCCCTGCCGCAGATTCCGCCGCGCA
ATGTCAACTGGTTCAAGGAAGGCAAGTGGGTGCATCTGGCCAAGGTCGCCTTCGAGAAGTACTTCATCCGCAAGATGAAA
AAAGGCTCGACCGAGCCGCTGTACGAGAAGTACGTGCTCGGCCTCATGGGCATCAAGAAACTCAAGTAA

Upstream 100 bases:

>100_bases
GACTTGCAGAAGATCGTTCAGGACGGCCTCGACGCCATGGTGCGCGTCTTCGAGTGGTGAGTCGCCTACCCAACCACACA
GCACCCCAGGAGAACAACAC

Downstream 100 bases:

>100_bases
ACAATTTCGGACTCCTGCCCCCTAAGCGCCTTCGGGCGCTTTTTTTATGGGGCGCGCTTTTTTTATGGCCGGCGGGCCGC
GCAGCTATAATTTCCGGTCC

Product: sulfide-quinone reductase

Products: NA

Alternate protein names: Sulfide-Quinone Reductase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; SulfideQuinone Oxidoreductase; Sulfide Quinone Reductase; Fad-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Oxidoreductase; Sulfide-Quinone Oxidoreductase; NAD(FAD)-Dependent Dehydrogenase; Pyridine Nucleotide-Disulphide Oxidoreductase; Sulfide Dehydrogenase; Quinone Reductase; FAD Dependent Oxidoreductase; FAD-Dependent Pyridine Nucleotide-Disulphideoxido Reductase; Sulfide-Quinone Reductase Related Protein; NADH Dehydrogenase FAD-Containing Subunit; Pyridine Nucleotide-Disulfide Oxidoreductase Family Protein; SulfideQuinone Reductase; Flavoprotein Reductase; Sulfide Dehydrogenase Related Protein

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MAHIVILGAGVGGMTMAYEMRESARAEDKVTVISNNSYFQFTPSNPWVGVNWRKRDDVTLEAAPYLNKKNIDFIPVGAAR
VHPDRNQIDLTDGRTVDYDFLVIATGPKLAFDEVPGLGPEGYTQSVCTVDHAQAAGRAWDDFVKNPGPIVVGAVQGASCY
GPAYEYAMIMDTDLRKRKIRDRVPMTYVTAEPYIGHLGLGGVGDSKGMLESVLRERHIKWICNAKVTKVEAGKMFVAEHN
DKGEVIKEHELPFGYSMMLPAFKGIDAVFGIEGLTNPRGFITIDPYQRNAKYPNVYSVGVCVAIPPVEVTPVPTGTPKTG
YMIESMVTATAHNIRAVLDGREPAEKATWNAICLADFGDTGAAFVALPQIPPRNVNWFKEGKWVHLAKVAFEKYFIRKMK
KGSTEPLYEKYVLGLMGIKKLK

Sequences:

>Translated_422_residues
MAHIVILGAGVGGMTMAYEMRESARAEDKVTVISNNSYFQFTPSNPWVGVNWRKRDDVTLEAAPYLNKKNIDFIPVGAAR
VHPDRNQIDLTDGRTVDYDFLVIATGPKLAFDEVPGLGPEGYTQSVCTVDHAQAAGRAWDDFVKNPGPIVVGAVQGASCY
GPAYEYAMIMDTDLRKRKIRDRVPMTYVTAEPYIGHLGLGGVGDSKGMLESVLRERHIKWICNAKVTKVEAGKMFVAEHN
DKGEVIKEHELPFGYSMMLPAFKGIDAVFGIEGLTNPRGFITIDPYQRNAKYPNVYSVGVCVAIPPVEVTPVPTGTPKTG
YMIESMVTATAHNIRAVLDGREPAEKATWNAICLADFGDTGAAFVALPQIPPRNVNWFKEGKWVHLAKVAFEKYFIRKMK
KGSTEPLYEKYVLGLMGIKKLK
>Mature_421_residues
AHIVILGAGVGGMTMAYEMRESARAEDKVTVISNNSYFQFTPSNPWVGVNWRKRDDVTLEAAPYLNKKNIDFIPVGAARV
HPDRNQIDLTDGRTVDYDFLVIATGPKLAFDEVPGLGPEGYTQSVCTVDHAQAAGRAWDDFVKNPGPIVVGAVQGASCYG
PAYEYAMIMDTDLRKRKIRDRVPMTYVTAEPYIGHLGLGGVGDSKGMLESVLRERHIKWICNAKVTKVEAGKMFVAEHND
KGEVIKEHELPFGYSMMLPAFKGIDAVFGIEGLTNPRGFITIDPYQRNAKYPNVYSVGVCVAIPPVEVTPVPTGTPKTGY
MIESMVTATAHNIRAVLDGREPAEKATWNAICLADFGDTGAAFVALPQIPPRNVNWFKEGKWVHLAKVAFEKYFIRKMKK
GSTEPLYEKYVLGLMGIKKLK

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10864011, Length=374, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534373, Length=300, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24657386, Length=329, Percent_Identity=23.4042553191489, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24657391, Length=329, Percent_Identity=23.4042553191489, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46567; Mature: 46436

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHIVILGAGVGGMTMAYEMRESARAEDKVTVISNNSYFQFTPSNPWVGVNWRKRDDVTL
CEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCEEECCCCCCCCEEE
EAAPYLNKKNIDFIPVGAARVHPDRNQIDLTDGRTVDYDFLVIATGPKLAFDEVPGLGPE
EECCCCCCCCCCEEECCCEEECCCCCEEECCCCCEEEEEEEEEECCCCEEHHCCCCCCCC
GYTQSVCTVDHAQAAGRAWDDFVKNPGPIVVGAVQGASCYGPAYEYAMIMDTDLRKRKIR
CCCCCEEEEHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
DRVPMTYVTAEPYIGHLGLGGVGDSKGMLESVLRERHIKWICNAKVTKVEAGKMFVAEHN
HCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCEEEEEECCEEEEEECC
DKGEVIKEHELPFGYSMMLPAFKGIDAVFGIEGLTNPRGFITIDPYQRNAKYPNVYSVGV
CCCCEEEECCCCCCHHHHHHHHCCCCCEEECCCCCCCCCEEEECCHHCCCCCCCEEEEEE
CVAIPPVEVTPVPTGTPKTGYMIESMVTATAHNIRAVLDGREPAEKATWNAICLADFGDT
EEEECCEEEECCCCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEEECCCC
GAAFVALPQIPPRNVNWFKEGKWVHLAKVAFEKYFIRKMKKGSTEPLYEKYVLGLMGIKK
CEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LK
CC
>Mature Secondary Structure 
AHIVILGAGVGGMTMAYEMRESARAEDKVTVISNNSYFQFTPSNPWVGVNWRKRDDVTL
EEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCEEECCCCCCCCEEE
EAAPYLNKKNIDFIPVGAARVHPDRNQIDLTDGRTVDYDFLVIATGPKLAFDEVPGLGPE
EECCCCCCCCCCEEECCCEEECCCCCEEECCCCCEEEEEEEEEECCCCEEHHCCCCCCCC
GYTQSVCTVDHAQAAGRAWDDFVKNPGPIVVGAVQGASCYGPAYEYAMIMDTDLRKRKIR
CCCCCEEEEHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
DRVPMTYVTAEPYIGHLGLGGVGDSKGMLESVLRERHIKWICNAKVTKVEAGKMFVAEHN
HCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCEEEEEECCEEEEEECC
DKGEVIKEHELPFGYSMMLPAFKGIDAVFGIEGLTNPRGFITIDPYQRNAKYPNVYSVGV
CCCCEEEECCCCCCHHHHHHHHCCCCCEEECCCCCCCCCEEEECCHHCCCCCCCEEEEEE
CVAIPPVEVTPVPTGTPKTGYMIESMVTATAHNIRAVLDGREPAEKATWNAICLADFGDT
EEEECCEEEECCCCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEEECCCC
GAAFVALPQIPPRNVNWFKEGKWVHLAKVAFEKYFIRKMKKGSTEPLYEKYVLGLMGIKK
CEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA