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The map label for this gene is trpG [H]

Identifier: 74318242

GI number: 74318242

Start: 2303788

End: 2304357

Strand: Reverse

Name: trpG [H]

Synonym: Tbd_2224

Alternate gene names: 74318242

Gene position: 2304357-2303788 (Counterclockwise)

Preceding gene: 74318243

Following gene: 74318241

Centisome position: 79.19

GC content: 62.63

Gene sequence:

>570_bases
ATGCTTTTGATGATCGACAACTACGACAGCTTCACCTACAACCTTGTGCAGTACTTCGGCGAGCTCGGTGAAGCGGTCAA
GGTCGTGCGCAACGACGAAATCGACCTCGCCGGAATCGCGACACTCGCGCCCGACCACATCGTCGTCTCGCCCGGCCCCT
GCACGCCCAACGAAGCCGGCGTCTCGGTGCCGCTGATCAAGGAATTTTCGGGGCGGATTCCGATCCTCGGCGTCTGCCTC
GGGCACCAGAGCATCGGTCAGGCCTTCGGCGGCAGGATCGTGCGCGCGAAGGAACTCATGCACGGCAAGACCTCGATGAT
CGAGCATCTGGACGCGGGCGTCTTCAAGGGCCTGCCCAATCCCTTCCGCGCCACGCGCTACCACTCGCTCGTGATCGAGC
GCGAATCGCTGCCCGACTGCCTGGAGATCACGGCCTGGAGCGACGACGGCGAGATCATGGGGGTACGTCACAAGACGCTT
GCGGTCGAGGGCGTGCAGTTCCATCCCGAATCGATCCTGACCGAGCACGGCCACGCGATGTTGAAGAACTTCCTGAAGGG
AACGCGATGA

Upstream 100 bases:

>100_bases
TTTATGGGGCGCGCTTTTTTTATGGCCGGCGGGCCGCGCAGCTATAATTTCCGGTCCGGCGGCGCGCGCGAGCGCGGGTG
CCGCGAGCCGAAGGACAGCC

Downstream 100 bases:

>100_bases
TCACGCCGCAGCAGGCGCTGACCCGCCTGGTCGAACAGCGCGAAATCTTTCACGACGAGATGCTCGCGCTGATGCGCCAG
ATCATGCGCGGCGAGCTCAC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MLLMIDNYDSFTYNLVQYFGELGEAVKVVRNDEIDLAGIATLAPDHIVVSPGPCTPNEAGVSVPLIKEFSGRIPILGVCL
GHQSIGQAFGGRIVRAKELMHGKTSMIEHLDAGVFKGLPNPFRATRYHSLVIERESLPDCLEITAWSDDGEIMGVRHKTL
AVEGVQFHPESILTEHGHAMLKNFLKGTR

Sequences:

>Translated_189_residues
MLLMIDNYDSFTYNLVQYFGELGEAVKVVRNDEIDLAGIATLAPDHIVVSPGPCTPNEAGVSVPLIKEFSGRIPILGVCL
GHQSIGQAFGGRIVRAKELMHGKTSMIEHLDAGVFKGLPNPFRATRYHSLVIERESLPDCLEITAWSDDGEIMGVRHKTL
AVEGVQFHPESILTEHGHAMLKNFLKGTR
>Mature_189_residues
MLLMIDNYDSFTYNLVQYFGELGEAVKVVRNDEIDLAGIATLAPDHIVVSPGPCTPNEAGVSVPLIKEFSGRIPILGVCL
GHQSIGQAFGGRIVRAKELMHGKTSMIEHLDAGVFKGLPNPFRATRYHSLVIERESLPDCLEITAWSDDGEIMGVRHKTL
AVEGVQFHPESILTEHGHAMLKNFLKGTR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=63.2432432432432, Blast_Score=258, Evalue=1e-70,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=43.3155080213904, Blast_Score=147, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=50.8108108108108, Blast_Score=202, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=33.4928229665072, Blast_Score=92, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281365319, Length=117, Percent_Identity=32.4786324786325, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20747; Mature: 20747

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNLVQYFGELGEAVKVVRNDEIDLAGIATLAPDHIVVSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCCC
VSVPLIKEFSGRIPILGVCLGHQSIGQAFGGRIVRAKELMHGKTSMIEHLDAGVFKGLPN
CCCHHHHHHCCCCCEEEEEECCHHHHHHHCCEEEHHHHHHCCHHHHHHHHHHHHHHCCCC
PFRATRYHSLVIERESLPDCLEITAWSDDGEIMGVRHKTLAVEGVQFHPESILTEHGHAM
CHHHHHHHHEEEECCCCCCEEEEEEECCCCCEEEEEEHEEEEECCEECHHHHHHHCCHHH
LKNFLKGTR
HHHHHCCCC
>Mature Secondary Structure
MLLMIDNYDSFTYNLVQYFGELGEAVKVVRNDEIDLAGIATLAPDHIVVSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCCC
VSVPLIKEFSGRIPILGVCLGHQSIGQAFGGRIVRAKELMHGKTSMIEHLDAGVFKGLPN
CCCHHHHHHCCCCCEEEEEECCHHHHHHHCCEEEHHHHHHCCHHHHHHHHHHHHHHCCCC
PFRATRYHSLVIERESLPDCLEITAWSDDGEIMGVRHKTLAVEGVQFHPESILTEHGHAM
CHHHHHHHHEEEECCCCCCEEEEEEECCCCCEEEEEEHEEEEECCEECHHHHHHHCCHHH
LKNFLKGTR
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]