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The map label for this gene is ruvA

Identifier: 74318231

GI number: 74318231

Start: 2292230

End: 2292805

Strand: Reverse

Name: ruvA

Synonym: Tbd_2213

Alternate gene names: 74318231

Gene position: 2292805-2292230 (Counterclockwise)

Preceding gene: 74318232

Following gene: 74318230

Centisome position: 78.8

GC content: 69.27

Gene sequence:

>576_bases
ATGATTGGCCGCATCACTGGCACGCTCGCCGCGAAGCAGCCGCCGCAGGTGCTCGTCGACGTCAATGGCGTCTGCTACGA
GATCGACGTGCCGATGAGCACCTTCTACAACCTGCCGGGCATCGGCGAGAAGGTCGCGCTGCTCACGCATCTGGCGATAC
GCGAGGACGCGCACCTGTTGTACGGCTTCGGCAGCGAGGTCGAACGCGCGGCGTTTCGCGAACTCCTCAAGGTTTCCGGC
ATCGGTGCGAAGACGGCGCTGTCGGTGCTGTCGGGACTCTCGGTGAACGACCTCTCTGCCGCGATCGCGGCGCAGGAAAT
CGGCCGCATCGTCAAGGTGCCGGGCATCGGCAAGAAGACCGCCGAGCGCCTGCTGCTCGAACTGAAGGGCAAGCCCGTGT
TCGCCGGCGCCCTGGCCAGCGTGCCGTCCGCCGGCGCGTCCGACGACGTGCGCCAGGCGCTGCTTGCGCTCGGTTACAAC
GAGCGCGAGACGGCCGCGACCGTGCGCGAGCTCCCCGCCGGTCTGGCGGTCGGCGAGGCCATCCGCCAGGCGCTGCGCGC
CCTGTCGCGGGCCTGA

Upstream 100 bases:

>100_bases
CCTTTTCGCCCTCGCGCCGGTTCGCTTCCGGCGGTGCGCGCCGCGGTCCCGTGCAGTCGCCGCGTATTGCGGATATCCTG
TTGAAAAAAATGGAGAACTT

Downstream 100 bases:

>100_bases
TCGGCATGCCTGCTCATGCGCCCGCCCGAGCCGCGACCGCCTCCTTGCGGCGCCATTTCGTATGGCTGCTGCTTGGGGTC
GTGCTGATGCTGGTTGGGGG

Product: DNA recombination protein, RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MIGRITGTLAAKQPPQVLVDVNGVCYEIDVPMSTFYNLPGIGEKVALLTHLAIREDAHLLYGFGSEVERAAFRELLKVSG
IGAKTALSVLSGLSVNDLSAAIAAQEIGRIVKVPGIGKKTAERLLLELKGKPVFAGALASVPSAGASDDVRQALLALGYN
ERETAATVRELPAGLAVGEAIRQALRALSRA

Sequences:

>Translated_191_residues
MIGRITGTLAAKQPPQVLVDVNGVCYEIDVPMSTFYNLPGIGEKVALLTHLAIREDAHLLYGFGSEVERAAFRELLKVSG
IGAKTALSVLSGLSVNDLSAAIAAQEIGRIVKVPGIGKKTAERLLLELKGKPVFAGALASVPSAGASDDVRQALLALGYN
ERETAATVRELPAGLAVGEAIRQALRALSRA
>Mature_191_residues
MIGRITGTLAAKQPPQVLVDVNGVCYEIDVPMSTFYNLPGIGEKVALLTHLAIREDAHLLYGFGSEVERAAFRELLKVSG
IGAKTALSVLSGLSVNDLSAAIAAQEIGRIVKVPGIGKKTAERLLLELKGKPVFAGALASVPSAGASDDVRQALLALGYN
ERETAATVRELPAGLAVGEAIRQALRALSRA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=44.7761194029851, Blast_Score=169, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_THIDA (Q3SGT1)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315971.1
- ProteinModelPortal:   Q3SGT1
- SMR:   Q3SGT1
- STRING:   Q3SGT1
- GeneID:   3671604
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2213
- NMPDR:   fig|292415.3.peg.2144
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q3SGT1
- BioCyc:   TDEN292415:TBD_2213-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 19954; Mature: 19954

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRITGTLAAKQPPQVLVDVNGVCYEIDVPMSTFYNLPGIGEKVALLTHLAIREDAHLL
CCCCCCCCCCCCCCCCEEEECCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHCCCCEE
YGFGSEVERAAFRELLKVSGIGAKTALSVLSGLSVNDLSAAIAAQEIGRIVKVPGIGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCCCCHHH
AERLLLELKGKPVFAGALASVPSAGASDDVRQALLALGYNERETAATVRELPAGLAVGEA
HHHHHHHHCCCCEEHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
IRQALRALSRA
HHHHHHHHHCC
>Mature Secondary Structure
MIGRITGTLAAKQPPQVLVDVNGVCYEIDVPMSTFYNLPGIGEKVALLTHLAIREDAHLL
CCCCCCCCCCCCCCCCEEEECCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHCCCCEE
YGFGSEVERAAFRELLKVSGIGAKTALSVLSGLSVNDLSAAIAAQEIGRIVKVPGIGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCCCCHHH
AERLLLELKGKPVFAGALASVPSAGASDDVRQALLALGYNERETAATVRELPAGLAVGEA
HHHHHHHHCCCCEEHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
IRQALRALSRA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA