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The map label for this gene is ruvB

Identifier: 74318229

GI number: 74318229

Start: 2289661

End: 2290686

Strand: Reverse

Name: ruvB

Synonym: Tbd_2211

Alternate gene names: 74318229

Gene position: 2290686-2289661 (Counterclockwise)

Preceding gene: 74318230

Following gene: 74318228

Centisome position: 78.72

GC content: 68.71

Gene sequence:

>1026_bases
ATGATCGAAACCGACCGCCTTATCGTACCGACCGCCGTCGGCCCGCAGGAAGAGCAGATCGAGCGCGCGCTGCGTCCGCG
CACGCTCGCCGAATACGTGGGCCAGGCCAAGGCGCGCGAGCAGCTCGAGATTTTCATCCACGCCGCGAGAAAGCGCAGCG
AGGCGCTCGACCACGTCCTGCTGTTCGGCCCGCCGGGGCTCGGCAAGACGACGCTCGCGCACATCATCGCGCGCGAAATG
GGGGTCAACCTGCGCCAGACTTCGGGTCCGGTGCTCGAGCGCGCCGGCGACCTCGCGGCGCTGTTGACCAACCTCGAACC
GCACGACGTGCTGTTCATCGACGAGATCCACCGTCTCTCGCCCGTAGTCGAGGAAGTGCTCTATCCCGCGCTCGAGGATT
TCCAGATCGACATCATGATCGGGGAGGGACCGGCGGCGCGCTCGGTCAAACTCGACCTGCCGCCGTTCACGCTCGTTGGC
GCGACGACGCGCGCAGGCATGCTGACCAACCCCCTGCGCGACCGTTTCGGCATCGTCGCGCGGCTCGAGTTCTATTCGGC
CGAGGAGCTCGGCTACATCGTCCACCGTTCGGCCGGTCTGCTGCAGATGAACCTCGACGAGGCCGGCGCGCTCGAGATCG
CGCGGCGCTCGCGCGGAACGCCGCGCATCGCCAACCGCCTGCTGCGGCGCGTCCGTGACTACGCGGAGGTCAAGGCGGGC
GGAGAGGCGACCGGCGCGGTCGCCGATGCCGCCCTGGTGATGCTCGACGTCGACCGCGCCGGGCTCGACGTCATGGACCG
CAAGCTGCTCGGCGCCGTGGTCGAGAAATTCATGGGCGGACCGGTCGGTCTCGACAATCTCGCGGCCGCGATCGGCGAAG
AGCGCGACACGATCGAGGACGTGCTCGAACCCTATCTCATCCAGCAGGGCTATCTGCAGCGCACGCCGCGCGGCCGGGTC
GCGACGCCGCTGGCTTACCGGCATCTCGGGATCGCCACGCCCGCCAGCGACGCCGAACTCTTCTGA

Upstream 100 bases:

>100_bases
AAGCCAAGGCCAGCGGGCGCAATCAGATCGTCATCGACGCGCCGCTGGACGAAACCGGCGCAGGGTAGAATTCCCGCATG
CCCGCTGTCCGCTGCGTTCC

Downstream 100 bases:

>100_bases
GTATGACGTTTCGCTGGCCCATCCGCGTGTACTGGGAAGACACCGACGCCGGCGGGGTCGTCTACTACGCGAATTATCTG
AAATTCATGGAGCGGGCGCG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MIETDRLIVPTAVGPQEEQIERALRPRTLAEYVGQAKAREQLEIFIHAARKRSEALDHVLLFGPPGLGKTTLAHIIAREM
GVNLRQTSGPVLERAGDLAALLTNLEPHDVLFIDEIHRLSPVVEEVLYPALEDFQIDIMIGEGPAARSVKLDLPPFTLVG
ATTRAGMLTNPLRDRFGIVARLEFYSAEELGYIVHRSAGLLQMNLDEAGALEIARRSRGTPRIANRLLRRVRDYAEVKAG
GEATGAVADAALVMLDVDRAGLDVMDRKLLGAVVEKFMGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGYLQRTPRGRV
ATPLAYRHLGIATPASDAELF

Sequences:

>Translated_341_residues
MIETDRLIVPTAVGPQEEQIERALRPRTLAEYVGQAKAREQLEIFIHAARKRSEALDHVLLFGPPGLGKTTLAHIIAREM
GVNLRQTSGPVLERAGDLAALLTNLEPHDVLFIDEIHRLSPVVEEVLYPALEDFQIDIMIGEGPAARSVKLDLPPFTLVG
ATTRAGMLTNPLRDRFGIVARLEFYSAEELGYIVHRSAGLLQMNLDEAGALEIARRSRGTPRIANRLLRRVRDYAEVKAG
GEATGAVADAALVMLDVDRAGLDVMDRKLLGAVVEKFMGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGYLQRTPRGRV
ATPLAYRHLGIATPASDAELF
>Mature_341_residues
MIETDRLIVPTAVGPQEEQIERALRPRTLAEYVGQAKAREQLEIFIHAARKRSEALDHVLLFGPPGLGKTTLAHIIAREM
GVNLRQTSGPVLERAGDLAALLTNLEPHDVLFIDEIHRLSPVVEEVLYPALEDFQIDIMIGEGPAARSVKLDLPPFTLVG
ATTRAGMLTNPLRDRFGIVARLEFYSAEELGYIVHRSAGLLQMNLDEAGALEIARRSRGTPRIANRLLRRVRDYAEVKAG
GEATGAVADAALVMLDVDRAGLDVMDRKLLGAVVEKFMGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGYLQRTPRGRV
ATPLAYRHLGIATPASDAELF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=72.4550898203593, Blast_Score=486, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_THIDA (Q3SGT3)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315969.1
- ProteinModelPortal:   Q3SGT3
- SMR:   Q3SGT3
- STRING:   Q3SGT3
- GeneID:   3671602
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2211
- NMPDR:   fig|292415.3.peg.2142
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q3SGT3
- ProtClustDB:   PRK00080
- BioCyc:   TDEN292415:TBD_2211-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37300; Mature: 37300

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETDRLIVPTAVGPQEEQIERALRPRTLAEYVGQAKAREQLEIFIHAARKRSEALDHVL
CCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
LFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEPHDVLFIDEIHRLS
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
PVVEEVLYPALEDFQIDIMIGEGPAARSVKLDLPPFTLVGATTRAGMLTNPLRDRFGIVA
HHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCCCEEEECCCHHCCHHHHHHHHHHCCEE
RLEFYSAEELGYIVHRSAGLLQMNLDEAGALEIARRSRGTPRIANRLLRRVRDYAEVKAG
EEEHHCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
GEATGAVADAALVMLDVDRAGLDVMDRKLLGAVVEKFMGGPVGLDNLAAAIGEERDTIED
CCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
VLEPYLIQQGYLQRTPRGRVATPLAYRHLGIATPASDAELF
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIETDRLIVPTAVGPQEEQIERALRPRTLAEYVGQAKAREQLEIFIHAARKRSEALDHVL
CCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
LFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEPHDVLFIDEIHRLS
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
PVVEEVLYPALEDFQIDIMIGEGPAARSVKLDLPPFTLVGATTRAGMLTNPLRDRFGIVA
HHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCCCEEEECCCHHCCHHHHHHHHHHCCEE
RLEFYSAEELGYIVHRSAGLLQMNLDEAGALEIARRSRGTPRIANRLLRRVRDYAEVKAG
EEEHHCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
GEATGAVADAALVMLDVDRAGLDVMDRKLLGAVVEKFMGGPVGLDNLAAAIGEERDTIED
CCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
VLEPYLIQQGYLQRTPRGRVATPLAYRHLGIATPASDAELF
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA