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The map label for this gene is adiA [H]

Identifier: 74318124

GI number: 74318124

Start: 2194463

End: 2196706

Strand: Reverse

Name: adiA [H]

Synonym: Tbd_2106

Alternate gene names: 74318124

Gene position: 2196706-2194463 (Counterclockwise)

Preceding gene: 74318125

Following gene: 74318123

Centisome position: 75.49

GC content: 63.41

Gene sequence:

>2244_bases
ATGCGCTTCCGTTTTCCCGTTGTCATCATCGACGAAGATTTCCGTTCGGAAAACGCGTCCGGCCTCGGTATACGGGCGCT
CGCCGAAGCGATCGAAAAAGAGGGTATGGAGGTGCTGGGCGTCACGAACTACGGCGACTTGACGTCGTTCGCCCAGCAAC
AGGCGCGTGCGTCAGCCTTCATCCTCTCGATCGACGACGAGGAACTCGGGGGCACCGCCGAGGACGCGACGGCAGCGCTC
GACAAACTGCGCGGCTTCGTCGAGGAAGTGCGCTTCCGCAACGGCGAGATTCCGATCTTCCTGCACGGCGAGACGCGTAC
CGCGCGACATATCCCGAACGACATCCTGCGCGAGCTCAACGGCTTCATCCACATGCTGGAAGACACGCCCGAGTTCCTCG
CCCGCTACATCGCGCGCGAGGCCCGCGCCTATCTCGATTCGCTGGTGCCGCCGTTCTTTCGCGCGCTCACCCATTACGCC
GCCGACGGCTCGTATTCGTGGCACTGCCCCGGTCACTCGGGCGGCGTCGCCTTCCTCAAGTCGCCGATCGGCCAGATGTT
CCACCAGTTCTTCGGTGAAAACCTGCTGCGCGCCGACGTCTGCAACGCCGTCGACGAACTCGGCCAGCTGCTCGACCACA
CCGGCCCGGTCGCCGCGTCGGAGCGCAATGCCGCGCGTATCTTCAATTGCGACCATCTCTTCTTCGTCACCAACGGCACC
TCGTCGTCGAACAAGATGGTGTGGCATGCGACGGTCGCGCCCGGCGACATCGTCGTCGTCGACCGCAACTGCCATAAATC
GATCCTGCACGCGATCATGATGTGCGGGGCGATCCCGATCTTCCTCACCCCGACGCGCAACCACTACGGCATCATCGGGC
CGATCCCGATGGACGAGTTCCGCCCGGAGAACATCGAGAAGAAAATCGCCGCGCATCCCTTTGCCAAGGAGGTCAAGGGG
CGGCCGCGCATCCTCACGATCACCCAGTCGACCTACGACGGCATCCTCTACAACGTCGACATGATCAAGGAGTTGCTCGG
CGACTATATCGACACGCTGCATTTCGACGAGGCCTGGCTGCCGCACGCGACCTTCCACGATTTCTACCGTGGCATGCACG
CGATCGGCAAGGACCGCCCACGCGCCAAGGACGCGCTGGTGTTTGCGACCCAGTCGACGCACAAGCTTCTGGCCGGCCTG
AGTCAGGCGTCGCAGATCCTGGTGCAGGATTCCGAGACGCGCAAGCTCGACTTCCATCGTTTCAACGAAGCCTATCTGAT
GCACATGTCGACTTCGCCCCAGTACGCGATCATCGCGTCGTGCGACGTCGCCGCCGCGATGATGGAGCCGCCCGGCGGCC
CGGCGCTGGTCGAGGAGTCGATCCGCGAGGCGCTGGATTTCCGCCGCGCGATGCGCAAGGTCGACGAGGAATTCGGCGAC
TCCTGGTGGTTCAAGGTCTGGGGGCCCGAGAAGCTCGCCGAGGAGGGCGTCGGCGACCGCGAGGACTGGATGCTCGAAGC
GGGCGCGCGCTGGCACGAGTTCGGCAAGATCGTGCCCGGCTTCAACATGCTCGACCCGATCAAGGCGACGGTCATCACCC
CCGGGCTCGACGTCGACGGCGCGTTCGCCGACTGGGGGATTCCGGCCGCGATCGTCACCAAGTACCTCGCCGAGCACGGC
GTCATCGTCGAGAAAACCGGACTTTATTCCTTCTTCATCATGTTCACGATCGGCATCACCAAGGGCCGCTGGAACACGCT
GGTGACGGCGTTGCAGCAGTTCAAGGCCGACTACGACGAGAACCAGCCGCTATGGCGCGTGCTGCCCGAGTTCATCGAGA
AGCACCCGCGCTACGAGAAGACCGGCCTCAAGGATCTTTGCGACCAGATCCACGCGATATACAAGGCCAAGGACGTCGCA
CGGCTCACCACCGAAATGTACCTCTCCGAGATGGCGCCCGCGATGCGTCCGGCCGAGGCCTTCGCGAAGATGGCGCATCG
CGAGATCGAACGCGTCGACGTCGACGCCCTCGAGGGACGCATCACGGCCATGCTCGTGACGCCGTATCCGCCCGGCATCC
CGTTGCTGATTCCCGGCGAGCGCTTCAACGCCACGATCGTGCGCTACCTGCAGTTCACGCGCGACTTCAACGAGAAATTC
CCGGGCTTCGAGAGCGACGTCCACGGTCTCGTCGAAGATATAGTCGATGGCAAGGCCCGCTATTACGTCGACTGCGTGAT
TTGA

Upstream 100 bases:

>100_bases
GGCGTGACCCTGCCCAAGATCTGAGTGGCCCGCGCGCGCTAAGCCGGCTGCCACACCGATCCCTCGGCGTCTTATCCACG
GCCTTATTCCAGGAGCCGCC

Downstream 100 bases:

>100_bases
ATCGATTGCGGTTGATTTGTCAGGCAAAAAGCGTAAGATGCGCAGTCCCCGCTCCGGCGGGGATTGTTTTTAAACCCTTG
CTCCACCGCACCGCAGCGGG

Product: ornithine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MRFRFPVVIIDEDFRSENASGLGIRALAEAIEKEGMEVLGVTNYGDLTSFAQQQARASAFILSIDDEELGGTAEDATAAL
DKLRGFVEEVRFRNGEIPIFLHGETRTARHIPNDILRELNGFIHMLEDTPEFLARYIAREARAYLDSLVPPFFRALTHYA
ADGSYSWHCPGHSGGVAFLKSPIGQMFHQFFGENLLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLFFVTNGT
SSSNKMVWHATVAPGDIVVVDRNCHKSILHAIMMCGAIPIFLTPTRNHYGIIGPIPMDEFRPENIEKKIAAHPFAKEVKG
RPRILTITQSTYDGILYNVDMIKELLGDYIDTLHFDEAWLPHATFHDFYRGMHAIGKDRPRAKDALVFATQSTHKLLAGL
SQASQILVQDSETRKLDFHRFNEAYLMHMSTSPQYAIIASCDVAAAMMEPPGGPALVEESIREALDFRRAMRKVDEEFGD
SWWFKVWGPEKLAEEGVGDREDWMLEAGARWHEFGKIVPGFNMLDPIKATVITPGLDVDGAFADWGIPAAIVTKYLAEHG
VIVEKTGLYSFFIMFTIGITKGRWNTLVTALQQFKADYDENQPLWRVLPEFIEKHPRYEKTGLKDLCDQIHAIYKAKDVA
RLTTEMYLSEMAPAMRPAEAFAKMAHREIERVDVDALEGRITAMLVTPYPPGIPLLIPGERFNATIVRYLQFTRDFNEKF
PGFESDVHGLVEDIVDGKARYYVDCVI

Sequences:

>Translated_747_residues
MRFRFPVVIIDEDFRSENASGLGIRALAEAIEKEGMEVLGVTNYGDLTSFAQQQARASAFILSIDDEELGGTAEDATAAL
DKLRGFVEEVRFRNGEIPIFLHGETRTARHIPNDILRELNGFIHMLEDTPEFLARYIAREARAYLDSLVPPFFRALTHYA
ADGSYSWHCPGHSGGVAFLKSPIGQMFHQFFGENLLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLFFVTNGT
SSSNKMVWHATVAPGDIVVVDRNCHKSILHAIMMCGAIPIFLTPTRNHYGIIGPIPMDEFRPENIEKKIAAHPFAKEVKG
RPRILTITQSTYDGILYNVDMIKELLGDYIDTLHFDEAWLPHATFHDFYRGMHAIGKDRPRAKDALVFATQSTHKLLAGL
SQASQILVQDSETRKLDFHRFNEAYLMHMSTSPQYAIIASCDVAAAMMEPPGGPALVEESIREALDFRRAMRKVDEEFGD
SWWFKVWGPEKLAEEGVGDREDWMLEAGARWHEFGKIVPGFNMLDPIKATVITPGLDVDGAFADWGIPAAIVTKYLAEHG
VIVEKTGLYSFFIMFTIGITKGRWNTLVTALQQFKADYDENQPLWRVLPEFIEKHPRYEKTGLKDLCDQIHAIYKAKDVA
RLTTEMYLSEMAPAMRPAEAFAKMAHREIERVDVDALEGRITAMLVTPYPPGIPLLIPGERFNATIVRYLQFTRDFNEKF
PGFESDVHGLVEDIVDGKARYYVDCVI
>Mature_747_residues
MRFRFPVVIIDEDFRSENASGLGIRALAEAIEKEGMEVLGVTNYGDLTSFAQQQARASAFILSIDDEELGGTAEDATAAL
DKLRGFVEEVRFRNGEIPIFLHGETRTARHIPNDILRELNGFIHMLEDTPEFLARYIAREARAYLDSLVPPFFRALTHYA
ADGSYSWHCPGHSGGVAFLKSPIGQMFHQFFGENLLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLFFVTNGT
SSSNKMVWHATVAPGDIVVVDRNCHKSILHAIMMCGAIPIFLTPTRNHYGIIGPIPMDEFRPENIEKKIAAHPFAKEVKG
RPRILTITQSTYDGILYNVDMIKELLGDYIDTLHFDEAWLPHATFHDFYRGMHAIGKDRPRAKDALVFATQSTHKLLAGL
SQASQILVQDSETRKLDFHRFNEAYLMHMSTSPQYAIIASCDVAAAMMEPPGGPALVEESIREALDFRRAMRKVDEEFGD
SWWFKVWGPEKLAEEGVGDREDWMLEAGARWHEFGKIVPGFNMLDPIKATVITPGLDVDGAFADWGIPAAIVTKYLAEHG
VIVEKTGLYSFFIMFTIGITKGRWNTLVTALQQFKADYDENQPLWRVLPEFIEKHPRYEKTGLKDLCDQIHAIYKAKDVA
RLTTEMYLSEMAPAMRPAEAFAKMAHREIERVDVDALEGRITAMLVTPYPPGIPLLIPGERFNATIVRYLQFTRDFNEKF
PGFESDVHGLVEDIVDGKARYYVDCVI

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=765, Percent_Identity=38.562091503268, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1790573, Length=710, Percent_Identity=37.4647887323944, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI1786384, Length=724, Percent_Identity=37.0165745856354, Blast_Score=480, Evalue=1e-136,
Organism=Escherichia coli, GI1786909, Length=680, Percent_Identity=33.5294117647059, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI87082193, Length=730, Percent_Identity=32.0547945205479, Blast_Score=364, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 84114; Mature: 84114

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFRFPVVIIDEDFRSENASGLGIRALAEAIEKEGMEVLGVTNYGDLTSFAQQQARASAF
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHEEE
ILSIDDEELGGTAEDATAALDKLRGFVEEVRFRNGEIPIFLHGETRTARHIPNDILRELN
EEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHCCCHHHHHHHH
GFIHMLEDTPEFLARYIAREARAYLDSLVPPFFRALTHYAADGSYSWHCPGHSGGVAFLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHH
SPIGQMFHQFFGENLLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLFFVTNGT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCC
SSSNKMVWHATVAPGDIVVVDRNCHKSILHAIMMCGAIPIFLTPTRNHYGIIGPIPMDEF
CCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHC
RPENIEKKIAAHPFAKEVKGRPRILTITQSTYDGILYNVDMIKELLGDYIDTLHFDEAWL
CCCCHHHHHHCCCCHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCC
PHATFHDFYRGMHAIGKDRPRAKDALVFATQSTHKLLAGLSQASQILVQDSETRKLDFHR
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHEECCCCCCCHHHC
FNEAYLMHMSTSPQYAIIASCDVAAAMMEPPGGPALVEESIREALDFRRAMRKVDEEFGD
CCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
SWWFKVWGPEKLAEEGVGDREDWMLEAGARWHEFGKIVPGFNMLDPIKATVITPGLDVDG
CEEEEEECHHHHHHCCCCCCHHHHHHCCCCHHHHCCCCCCCCCCCCCHHEEECCCCCCCC
AFADWGIPAAIVTKYLAEHGVIVEKTGLYSFFIMFTIGITKGRWNTLVTALQQFKADYDE
CCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
NQPLWRVLPEFIEKHPRYEKTGLKDLCDQIHAIYKAKDVARLTTEMYLSEMAPAMRPAEA
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FAKMAHREIERVDVDALEGRITAMLVTPYPPGIPLLIPGERFNATIVRYLQFTRDFNEKF
HHHHHHHHHHHCCHHHHCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
PGFESDVHGLVEDIVDGKARYYVDCVI
CCCCHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MRFRFPVVIIDEDFRSENASGLGIRALAEAIEKEGMEVLGVTNYGDLTSFAQQQARASAF
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHEEE
ILSIDDEELGGTAEDATAALDKLRGFVEEVRFRNGEIPIFLHGETRTARHIPNDILRELN
EEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHCCCHHHHHHHH
GFIHMLEDTPEFLARYIAREARAYLDSLVPPFFRALTHYAADGSYSWHCPGHSGGVAFLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHH
SPIGQMFHQFFGENLLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLFFVTNGT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCC
SSSNKMVWHATVAPGDIVVVDRNCHKSILHAIMMCGAIPIFLTPTRNHYGIIGPIPMDEF
CCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHC
RPENIEKKIAAHPFAKEVKGRPRILTITQSTYDGILYNVDMIKELLGDYIDTLHFDEAWL
CCCCHHHHHHCCCCHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCC
PHATFHDFYRGMHAIGKDRPRAKDALVFATQSTHKLLAGLSQASQILVQDSETRKLDFHR
CCHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHEECCCCCCCHHHC
FNEAYLMHMSTSPQYAIIASCDVAAAMMEPPGGPALVEESIREALDFRRAMRKVDEEFGD
CCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
SWWFKVWGPEKLAEEGVGDREDWMLEAGARWHEFGKIVPGFNMLDPIKATVITPGLDVDG
CEEEEEECHHHHHHCCCCCCHHHHHHCCCCHHHHCCCCCCCCCCCCCHHEEECCCCCCCC
AFADWGIPAAIVTKYLAEHGVIVEKTGLYSFFIMFTIGITKGRWNTLVTALQQFKADYDE
CCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
NQPLWRVLPEFIEKHPRYEKTGLKDLCDQIHAIYKAKDVARLTTEMYLSEMAPAMRPAEA
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FAKMAHREIERVDVDALEGRITAMLVTPYPPGIPLLIPGERFNATIVRYLQFTRDFNEKF
HHHHHHHHHHHCCHHHHCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
PGFESDVHGLVEDIVDGKARYYVDCVI
CCCCHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]