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The map label for this gene is dcd

Identifier: 74318125

GI number: 74318125

Start: 2196783

End: 2197349

Strand: Reverse

Name: dcd

Synonym: Tbd_2107

Alternate gene names: 74318125

Gene position: 2197349-2196783 (Counterclockwise)

Preceding gene: 74318126

Following gene: 74318124

Centisome position: 75.52

GC content: 61.38

Gene sequence:

>567_bases
ATGAGCATCAAGTCCGACCGATGGATCCGCCGCATGGCGGCCGAGCATGGCATGATCGAACCGTTCGAAGCCGGACAGAT
CAAGCAGGCAGCGGGGCGATCCATCGTGTCGTACGGCACGTCGAGCTACGGCTACGACGTGCGCTGCGCGAGCGAATTCA
AGCTCTTCACGGACATCAATACGACGATCGTCGACCCCAAGGCCTTCGATCCGAACTCCTTCGTCGAGGTCAAGGGCGAT
TCCTGCATCATTCCGCCCAACTCCTTCGCGCTCGCGCGGACCGTCGAATATTTCCGTATTCCGCGCAGCGTTCTGACGAT
CTGTCTGGGTAAAAGCACCTACGCCCGCTGCGGCATCATCGTCAACGTGACTCCGCTCGAACCCGAGTGGGAGGGGCACG
TCACCCTCGAGTTTTCGAACACCACGCCGCTGCCTGCGCGCATCTATGCGAACGAGGGCGTCGCCCAGATGCTGTTTCTC
GAGTCCGACGAGGTGTGCGAGACCTCGTATCGCGATCGCGGCGGCAAATACCAGGGCCAGGTCGGCGTGACCCTGCCCAA
GATCTGA

Upstream 100 bases:

>100_bases
AAATCTACAAGCAGATCGCGCGCCGCGTTGCTGTTAAGATTGGCGAGACGGCCGTCGACCATTCGGCCAAATTCCCCAAT
ATCGTCATTTCCAACACCTG

Downstream 100 bases:

>100_bases
GTGGCCCGCGCGCGCTAAGCCGGCTGCCACACCGATCCCTCGGCGTCTTATCCACGGCCTTATTCCAGGAGCCGCCATGC
GCTTCCGTTTTCCCGTTGTC

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSIKSDRWIRRMAAEHGMIEPFEAGQIKQAAGRSIVSYGTSSYGYDVRCASEFKLFTDINTTIVDPKAFDPNSFVEVKGD
SCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFL
ESDEVCETSYRDRGGKYQGQVGVTLPKI

Sequences:

>Translated_188_residues
MSIKSDRWIRRMAAEHGMIEPFEAGQIKQAAGRSIVSYGTSSYGYDVRCASEFKLFTDINTTIVDPKAFDPNSFVEVKGD
SCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFL
ESDEVCETSYRDRGGKYQGQVGVTLPKI
>Mature_187_residues
SIKSDRWIRRMAAEHGMIEPFEAGQIKQAAGRSIVSYGTSSYGYDVRCASEFKLFTDINTTIVDPKAFDPNSFVEVKGDS
CIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFLE
SDEVCETSYRDRGGKYQGQVGVTLPKI

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_THIDA (Q3SH29)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315865.1
- ProteinModelPortal:   Q3SH29
- SMR:   Q3SH29
- STRING:   Q3SH29
- GeneID:   3672879
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2107
- NMPDR:   fig|292415.3.peg.2283
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- PhylomeDB:   Q3SH29
- ProtClustDB:   PRK00416
- BioCyc:   TDEN292415:TBD_2107-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20917; Mature: 20786

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKSDRWIRRMAAEHGMIEPFEAGQIKQAAGRSIVSYGTSSYGYDVRCASEFKLFTDIN
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEECCCCCCCCEEEEECCCEEEEECCC
TTIVDPKAFDPNSFVEVKGDSCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGII
EEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHCCHHHHHHHCCCCCHHHCEEE
VNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFLESDEVCETSYRDRGGKYQGQ
EEEECCCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCCCE
VGVTLPKI
EEEEECCC
>Mature Secondary Structure 
SIKSDRWIRRMAAEHGMIEPFEAGQIKQAAGRSIVSYGTSSYGYDVRCASEFKLFTDIN
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEECCCCCCCCEEEEECCCEEEEECCC
TTIVDPKAFDPNSFVEVKGDSCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGII
EEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHCCHHHHHHHCCCCCHHHCEEE
VNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFLESDEVCETSYRDRGGKYQGQ
EEEECCCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCCCE
VGVTLPKI
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA