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The map label for this gene is kup

Identifier: 74318083

GI number: 74318083

Start: 2157499

End: 2159373

Strand: Reverse

Name: kup

Synonym: Tbd_2065

Alternate gene names: 74318083

Gene position: 2159373-2157499 (Counterclockwise)

Preceding gene: 74318085

Following gene: 74318081

Centisome position: 74.21

GC content: 66.67

Gene sequence:

>1875_bases
TTGAGCCAGCCTCACAGCGTCCCAAATACGCGTGCGCTCGCCCTCGGCGCGCTCGGCGTGGTGTTCGGCGACATCGGCAC
CAGCCCCCTCTACACGATGAAGGAGGTGTTCGGCGGTCACCACCTCGCCCTGACCCAGGACAATGTGCTCGGCATCCTGT
CGCTGATCTTCTGGGCCCTGATCCTGGTCGTGTCGCTCAAGTACGTCCTCGTCATCATGCGTGCGGACAACAAGGGCGAA
GGCGGCATACTGGCGCTGCTGTCCCTGGTCCAGGGGCAGGCGCCGCTGCGCTCGAGAGCCCGCTGGATCATCATGTCGCT
GGGTTTTCTCGGTGCGTCGCTGTTCTTCGGCGACAGTCTCATCACACCGGCGATCTCGGTGCTGTCGGCGGTCGAGGGGC
TCGAGATCGGCGCGCCGGCCTTGCATCCCTTCATCCTTCCGCTCGCCCTCGGCATCCTCGTCGGCCTGTTTGCGATCCAG
CGCCGCGGGACGGCAAGCATCGGGCGGCTGTTCGGGCCGATCATGCTGCTCTGGTTCGCGGTCCTCGGCGTGCTCGGTGC
GATCGGCATTGCCAAACATCCCCAGGTGCTCGCGGCGCTGCTGCCGATTCATGCGATCCAGTTTTTCATGACCCACGGCA
CGGCGGGTTTCCTGATCCTCGGTGCGGTGGTCCTCGCGATCACGGGCGCCGAGGCGCTCTATGCGGACATGGGCCATTTC
GGCACGCGGCCGATCCGTCTGACGTGGTTCGGCTTCGTGCTGCCGGCGCTGGTCGTCAATTACTTCGGCCAGGGCGCGCT
GCTGCTGGCCGAGCCCGCGGCCGTGCGCAATCCGTTCTACATGCTCGCGCCCGACTGGGCCTTGTACCCGATGGTCGCGC
TGGCCACGGCGGCGACGGTGATCGCGTCCCAGGCGGTCATCTCGGGCGCCTTCTCGGTCACCCGGCAAGTGGTGCAGATG
GGCTACGCTCCGCGGCTCGTGATCCGCCACACGTCGGCGACGGCGGCGGGGCAGATCTATATTCCCTTCGTCAACTGGAC
GCTGGCGGCCGGCGTCGCGCTGCTCGTGCTCGGCTTTCAAAGCTCGAGCAATCTCGCCGCGGCCTACGGCATCGCCGTGA
CGGCGACCTTCGCCATCGACACCGTCCTGCTCGCGCTGCTCATGCGCGTCAACTGGAACCTCGGGCGCGCGCCGACGCTG
GTCGCAGCGGCGTTGTTTCTGACCCTCGATCTCGCGTTCTTCGGCGCGAATGCGGTGAAGATCCCCGAAGGCGGCTGGTT
TCCGCTGGTCGTGGCGGTCGTCGTGTTCACGATCCTCGTGACCTGGAGACGGGGTCGCGAAATCGTCGGCGCGCGCCTGC
ACGAGCGCGGGCTGCCCCTCGCGCCGTTCGTCGAATCGCTGCTGGCGCATCCTCCGGCGCGGGTCGGGGGCACGGCGGTG
TTCATGACGACCGACCCGAGCGGTGTGCCCCTGGCGCTGCTGCACAACCTCAAGCACAACAAGGTTCTGCACGAGCGGGT
GGTGATCCTCAACGTCCGTTATGGCGAGGTGCCCTACGTGCCGGCCGAGCACCGGCTCGCGGTGACGAAGCTCGGCGAGG
GCGTGTTCCACGTCGTCGTGCGCTACGGTTTCATGGACGACGTCGACATTCCAAAGGCGCTGGCCGAATGCCCTTGCGGC
ATGGATTTCGACATGATGGATACAACCTTCTTCCTGAGCCGGGAGAACCTGATTCCCGCGCGCGGCGACGGCGGGATGAT
GGTGTGGCGCGAGCACCTGTTCGCAACGATGGCGCGCAACGCGGCAAGCCCGATGACCTTTTTCCGGATTCCGCCGAACC
GCGTCGTCGAGCTCGGCGCGCAGCTCGAGATCTAG

Upstream 100 bases:

>100_bases
CGTCATCGCTCGCATCCGAGGTCGTCGCGGGCGTATCATCTGCGACCGCCTGCCGCGCCGCGGCCGGCCAATCGATACAA
CCCTACGACAAGCAAAGACA

Downstream 100 bases:

>100_bases
GATGCACCACCCGCCGCGCGCCACCGGGGTGCGCAGCGACGGCGCGCCGAGGCTGCCTACGCCGCGCGCAGGCTCCGCCC
GCGCGCCCGCTCGATCAGGT

Product: potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MSQPHSVPNTRALALGALGVVFGDIGTSPLYTMKEVFGGHHLALTQDNVLGILSLIFWALILVVSLKYVLVIMRADNKGE
GGILALLSLVQGQAPLRSRARWIIMSLGFLGASLFFGDSLITPAISVLSAVEGLEIGAPALHPFILPLALGILVGLFAIQ
RRGTASIGRLFGPIMLLWFAVLGVLGAIGIAKHPQVLAALLPIHAIQFFMTHGTAGFLILGAVVLAITGAEALYADMGHF
GTRPIRLTWFGFVLPALVVNYFGQGALLLAEPAAVRNPFYMLAPDWALYPMVALATAATVIASQAVISGAFSVTRQVVQM
GYAPRLVIRHTSATAAGQIYIPFVNWTLAAGVALLVLGFQSSSNLAAAYGIAVTATFAIDTVLLALLMRVNWNLGRAPTL
VAAALFLTLDLAFFGANAVKIPEGGWFPLVVAVVVFTILVTWRRGREIVGARLHERGLPLAPFVESLLAHPPARVGGTAV
FMTTDPSGVPLALLHNLKHNKVLHERVVILNVRYGEVPYVPAEHRLAVTKLGEGVFHVVVRYGFMDDVDIPKALAECPCG
MDFDMMDTTFFLSRENLIPARGDGGMMVWREHLFATMARNAASPMTFFRIPPNRVVELGAQLEI

Sequences:

>Translated_624_residues
MSQPHSVPNTRALALGALGVVFGDIGTSPLYTMKEVFGGHHLALTQDNVLGILSLIFWALILVVSLKYVLVIMRADNKGE
GGILALLSLVQGQAPLRSRARWIIMSLGFLGASLFFGDSLITPAISVLSAVEGLEIGAPALHPFILPLALGILVGLFAIQ
RRGTASIGRLFGPIMLLWFAVLGVLGAIGIAKHPQVLAALLPIHAIQFFMTHGTAGFLILGAVVLAITGAEALYADMGHF
GTRPIRLTWFGFVLPALVVNYFGQGALLLAEPAAVRNPFYMLAPDWALYPMVALATAATVIASQAVISGAFSVTRQVVQM
GYAPRLVIRHTSATAAGQIYIPFVNWTLAAGVALLVLGFQSSSNLAAAYGIAVTATFAIDTVLLALLMRVNWNLGRAPTL
VAAALFLTLDLAFFGANAVKIPEGGWFPLVVAVVVFTILVTWRRGREIVGARLHERGLPLAPFVESLLAHPPARVGGTAV
FMTTDPSGVPLALLHNLKHNKVLHERVVILNVRYGEVPYVPAEHRLAVTKLGEGVFHVVVRYGFMDDVDIPKALAECPCG
MDFDMMDTTFFLSRENLIPARGDGGMMVWREHLFATMARNAASPMTFFRIPPNRVVELGAQLEI
>Mature_623_residues
SQPHSVPNTRALALGALGVVFGDIGTSPLYTMKEVFGGHHLALTQDNVLGILSLIFWALILVVSLKYVLVIMRADNKGEG
GILALLSLVQGQAPLRSRARWIIMSLGFLGASLFFGDSLITPAISVLSAVEGLEIGAPALHPFILPLALGILVGLFAIQR
RGTASIGRLFGPIMLLWFAVLGVLGAIGIAKHPQVLAALLPIHAIQFFMTHGTAGFLILGAVVLAITGAEALYADMGHFG
TRPIRLTWFGFVLPALVVNYFGQGALLLAEPAAVRNPFYMLAPDWALYPMVALATAATVIASQAVISGAFSVTRQVVQMG
YAPRLVIRHTSATAAGQIYIPFVNWTLAAGVALLVLGFQSSSNLAAAYGIAVTATFAIDTVLLALLMRVNWNLGRAPTLV
AAALFLTLDLAFFGANAVKIPEGGWFPLVVAVVVFTILVTWRRGREIVGARLHERGLPLAPFVESLLAHPPARVGGTAVF
MTTDPSGVPLALLHNLKHNKVLHERVVILNVRYGEVPYVPAEHRLAVTKLGEGVFHVVVRYGFMDDVDIPKALAECPCGM
DFDMMDTTFFLSRENLIPARGDGGMMVWREHLFATMARNAASPMTFFRIPPNRVVELGAQLEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=625, Percent_Identity=49.28, Blast_Score=591, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_THIDA (Q3SH71)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315823.1
- STRING:   Q3SH71
- GeneID:   3672236
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2065
- NMPDR:   fig|292415.3.peg.2221
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   KECFSPE
- PhylomeDB:   Q3SH71
- BioCyc:   TDEN292415:TBD_2065-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 66903; Mature: 66772

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c84c5d4)-; HASH(0x1bebd838)-; HASH(0x1d272e28)-; HASH(0x1d7985e0)-; HASH(0x1d7e605c)-; HASH(0x1cc30814)-; HASH(0x1cd3567c)-; HASH(0x1d6b4988)-; HASH(0x1d65f13c)-; HASH(0x1d59547c)-; HASH(0x1cd284ec)-; HASH(0x1b158a1c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPHSVPNTRALALGALGVVFGDIGTSPLYTMKEVFGGHHLALTQDNVLGILSLIFWAL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
ILVVSLKYVLVIMRADNKGEGGILALLSLVQGQAPLRSRARWIIMSLGFLGASLFFGDSL
HHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
ITPAISVLSAVEGLEIGAPALHPFILPLALGILVGLFAIQRRGTASIGRLFGPIMLLWFA
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLGVLGAIGIAKHPQVLAALLPIHAIQFFMTHGTAGFLILGAVVLAITGAEALYADMGHF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCC
GTRPIRLTWFGFVLPALVVNYFGQGALLLAEPAAVRNPFYMLAPDWALYPMVALATAATV
CCCCEEEHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCEEEECCCHHHHHHHHHHHHHHH
IASQAVISGAFSVTRQVVQMGYAPRLVIRHTSATAAGQIYIPFVNWTLAAGVALLVLGFQ
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHEECC
SSSNLAAAYGIAVTATFAIDTVLLALLMRVNWNLGRAPTLVAAALFLTLDLAFFGANAVK
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
IPEGGWFPLVVAVVVFTILVTWRRGREIVGARLHERGLPLAPFVESLLAHPPARVGGTAV
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEE
FMTTDPSGVPLALLHNLKHNKVLHERVVILNVRYGEVPYVPAEHRLAVTKLGEGVFHVVV
EEEECCCCCHHHHHHCCHHHHHHHCEEEEEEEEECCCCCCCCCCCEEHHHHCCHHHHHHH
RYGFMDDVDIPKALAECPCGMDFDMMDTTFFLSRENLIPARGDGGMMVWREHLFATMARN
HHCCCCCCCHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHC
AASPMTFFRIPPNRVVELGAQLEI
CCCCCEEEECCCHHHHHCCCCCCH
>Mature Secondary Structure 
SQPHSVPNTRALALGALGVVFGDIGTSPLYTMKEVFGGHHLALTQDNVLGILSLIFWAL
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
ILVVSLKYVLVIMRADNKGEGGILALLSLVQGQAPLRSRARWIIMSLGFLGASLFFGDSL
HHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
ITPAISVLSAVEGLEIGAPALHPFILPLALGILVGLFAIQRRGTASIGRLFGPIMLLWFA
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLGVLGAIGIAKHPQVLAALLPIHAIQFFMTHGTAGFLILGAVVLAITGAEALYADMGHF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCC
GTRPIRLTWFGFVLPALVVNYFGQGALLLAEPAAVRNPFYMLAPDWALYPMVALATAATV
CCCCEEEHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCEEEECCCHHHHHHHHHHHHHHH
IASQAVISGAFSVTRQVVQMGYAPRLVIRHTSATAAGQIYIPFVNWTLAAGVALLVLGFQ
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHEECC
SSSNLAAAYGIAVTATFAIDTVLLALLMRVNWNLGRAPTLVAAALFLTLDLAFFGANAVK
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
IPEGGWFPLVVAVVVFTILVTWRRGREIVGARLHERGLPLAPFVESLLAHPPARVGGTAV
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEE
FMTTDPSGVPLALLHNLKHNKVLHERVVILNVRYGEVPYVPAEHRLAVTKLGEGVFHVVV
EEEECCCCCHHHHHHCCHHHHHHHCEEEEEEEEECCCCCCCCCCCEEHHHHCCHHHHHHH
RYGFMDDVDIPKALAECPCGMDFDMMDTTFFLSRENLIPARGDGGMMVWREHLFATMARN
HHCCCCCCCHHHHHHHCCCCCCCCHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHC
AASPMTFFRIPPNRVVELGAQLEI
CCCCCEEEECCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA