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The map label for this gene is glk [H]

Identifier: 74318080

GI number: 74318080

Start: 2153350

End: 2154348

Strand: Reverse

Name: glk [H]

Synonym: Tbd_2062

Alternate gene names: 74318080

Gene position: 2154348-2153350 (Counterclockwise)

Preceding gene: 74318081

Following gene: 74318079

Centisome position: 74.04

GC content: 70.37

Gene sequence:

>999_bases
ATGGAGTGGATCGCAGGCGACATCGGAGGAACGAAGAGCTGGCTCGTGTGGATCGGGCCGCCTGGCGACGGCCTGCACCC
GCGCTTCGAGCGCGTCTACCCGAGCGCCGACTTCGTCTCGGCCGAAGCCCTGCTGCGGCAGTTTCTCGCCGACTCGGGGA
TACAGGGACGGCCCGACGGCCTGATCCTGGCCGTCGCCGGCCCGTCGCAGGCCGAGCACGTCAAGCTCACCAACCTCGAC
TGGTGGATCGACGCGGCCGAGCTCCAGCTCGCGCTCGGCATTCCCCAGGTCCACATCGTCAACGATTTCGAGGCTGCCGC
CGCGGGACTCGCGACCCTGGTGCCGGCCGACTACGTCGAGATCAACCCGGGGCAGCCCGACCCGCTCGGCGTGCGCGCGA
TCACGGGCGCCGGGACCGGGCTCGGCCTGGCCTTCCTCGTCCATGACCCGGCAGGGCGGGAAACGAGCTACCCGACCGAA
GGCGGCCACGTCGACTTTGCGCCCGCCAACGCCATGCAGGATCGGCTGCTGAAGCGACTGCGCAAGCAATACGGTCACGT
CTCCTGGGAGCGCGTCGTCTCCGGGTCGGCGATGTCCGAGCTCTATGCATTCTGCTGCGTCGAACTTGGCACCACGCCGT
GCTCGGCGTCGTGCGACGGCGCCTGCCTCGTCGCTGCGGCGGCGGCGGACGACATCGCGGCCGAGGCTGCGCTCGATCTC
TTTGTCGACCTCTACGGCGCCTGGGTCGGCAACGTCGCCTTGCTCTACCGTCCGCGCGGCGGGCTCTACATCGCCGGCGG
CGTCAGCGCGCACCTGCAGAAGCGCATCGCGGCGCCGCGCTTCATGGCCGCGGCGCTCGACAAGGGGCGCATGCGTCGCG
TCGTCGAAAGCACACCGATATTTCTGATCACGAGCCCGCGGCTCGGCGTGCAGGGCGCGCTGGCCCTGCGCGAAGCCGCG
GCGCACAGCCGGCGCGACCGCCGGACCCATGAACGATAA

Upstream 100 bases:

>100_bases
TGCACGCCGACGCGCCCGTCGCGGGACACGACGCCTCGACCAACGCGCTGATCAACCACTACCGTCGCATGACGCAGCCG
CATCCCGGGCTCTGAGCGGC

Downstream 100 bases:

>100_bases
AGCCAGGGAGGAGCAGCAGATGACGATTTCGAAGGACGATCAAGCCCGTCTCTACCGTTATTACACCGAGCCGACGCTGG
TGACCGAACTCACCCGCAAG

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEWIAGDIGGTKSWLVWIGPPGDGLHPRFERVYPSADFVSAEALLRQFLADSGIQGRPDGLILAVAGPSQAEHVKLTNLD
WWIDAAELQLALGIPQVHIVNDFEAAAAGLATLVPADYVEINPGQPDPLGVRAITGAGTGLGLAFLVHDPAGRETSYPTE
GGHVDFAPANAMQDRLLKRLRKQYGHVSWERVVSGSAMSELYAFCCVELGTTPCSASCDGACLVAAAAADDIAAEAALDL
FVDLYGAWVGNVALLYRPRGGLYIAGGVSAHLQKRIAAPRFMAAALDKGRMRRVVESTPIFLITSPRLGVQGALALREAA
AHSRRDRRTHER

Sequences:

>Translated_332_residues
MEWIAGDIGGTKSWLVWIGPPGDGLHPRFERVYPSADFVSAEALLRQFLADSGIQGRPDGLILAVAGPSQAEHVKLTNLD
WWIDAAELQLALGIPQVHIVNDFEAAAAGLATLVPADYVEINPGQPDPLGVRAITGAGTGLGLAFLVHDPAGRETSYPTE
GGHVDFAPANAMQDRLLKRLRKQYGHVSWERVVSGSAMSELYAFCCVELGTTPCSASCDGACLVAAAAADDIAAEAALDL
FVDLYGAWVGNVALLYRPRGGLYIAGGVSAHLQKRIAAPRFMAAALDKGRMRRVVESTPIFLITSPRLGVQGALALREAA
AHSRRDRRTHER
>Mature_332_residues
MEWIAGDIGGTKSWLVWIGPPGDGLHPRFERVYPSADFVSAEALLRQFLADSGIQGRPDGLILAVAGPSQAEHVKLTNLD
WWIDAAELQLALGIPQVHIVNDFEAAAAGLATLVPADYVEINPGQPDPLGVRAITGAGTGLGLAFLVHDPAGRETSYPTE
GGHVDFAPANAMQDRLLKRLRKQYGHVSWERVVSGSAMSELYAFCCVELGTTPCSASCDGACLVAAAAADDIAAEAALDL
FVDLYGAWVGNVALLYRPRGGLYIAGGVSAHLQKRIAAPRFMAAALDKGRMRRVVESTPIFLITSPRLGVQGALALREAA
AHSRRDRRTHER

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=321, Percent_Identity=33.9563862928349, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35409; Mature: 35409

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWIAGDIGGTKSWLVWIGPPGDGLHPRFERVYPSADFVSAEALLRQFLADSGIQGRPDG
CCEECCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LILAVAGPSQAEHVKLTNLDWWIDAAELQLALGIPQVHIVNDFEAAAAGLATLVPADYVE
EEEEEECCCCCCEEEEECCCEEEEHHHEEEEECCCEEEEECCHHHHHHHHHHHCCCCEEE
INPGQPDPLGVRAITGAGTGLGLAFLVHDPAGRETSYPTEGGHVDFAPANAMQDRLLKRL
ECCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHH
RKQYGHVSWERVVSGSAMSELYAFCCVELGTTPCSASCDGACLVAAAAADDIAAEAALDL
HHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
FVDLYGAWVGNVALLYRPRGGLYIAGGVSAHLQKRIAAPRFMAAALDKGRMRRVVESTPI
HHHHHHHHHCCEEEEEECCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCE
FLITSPRLGVQGALALREAAAHSRRDRRTHER
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEWIAGDIGGTKSWLVWIGPPGDGLHPRFERVYPSADFVSAEALLRQFLADSGIQGRPDG
CCEECCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
LILAVAGPSQAEHVKLTNLDWWIDAAELQLALGIPQVHIVNDFEAAAAGLATLVPADYVE
EEEEEECCCCCCEEEEECCCEEEEHHHEEEEECCCEEEEECCHHHHHHHHHHHCCCCEEE
INPGQPDPLGVRAITGAGTGLGLAFLVHDPAGRETSYPTEGGHVDFAPANAMQDRLLKRL
ECCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHH
RKQYGHVSWERVVSGSAMSELYAFCCVELGTTPCSASCDGACLVAAAAADDIAAEAALDL
HHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
FVDLYGAWVGNVALLYRPRGGLYIAGGVSAHLQKRIAAPRFMAAALDKGRMRRVVESTPI
HHHHHHHHHCCEEEEEECCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCE
FLITSPRLGVQGALALREAAAHSRRDRRTHER
EEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA