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The map label for this gene is dgk [H]

Identifier: 74318070

GI number: 74318070

Start: 2139898

End: 2140539

Strand: Direct

Name: dgk [H]

Synonym: Tbd_2052

Alternate gene names: 74318070

Gene position: 2139898-2140539 (Clockwise)

Preceding gene: 74318069

Following gene: 74318071

Centisome position: 73.54

GC content: 64.49

Gene sequence:

>642_bases
ATGACGTCATCCCGCTACCGTTACATCGTCGTCGAAGGCCCGATCGGCGCCGGCAAGACCAGTCTCACGCACAAGCTGGC
CGAACGTCTCGGCGCCGACCTGCTGCTCGAGAACGCGGGCGACAACCCTTTCCTGCCGCGCTTCTATCAGGAACCGCGCC
GTTACGCGCTGCCGACGCAGCTGCATTTCCTGTTCGACCGCTCGCGCCAGTTGCGTGATCTTGGCCAGGGCGACCTGTTC
CGCAGCGGAACGGTGTCGGACTTCCTGATCGACAAGGACATGCTGTTCGCGCGCCTGAATCTCGACGACGACGAGTTCGA
GCTCTACCAGAAGGTCTACGCCGACCTCGCGCCGCAGGCGGCGACGCCCGATCTCGTGATCTACCTGCAGGCGCCGACGG
AGACGCTGCACGAGCGCGTCCGTCGCCGCGGGATCGATTTCGAGCGCGGCATGGACGCGGCGTATCTGGAGCGGCTCGCC
AACAGCTACAGCGAATTCTTCCATCGCTACGACGCGGCGCCGCTTCTGATCGTCAACACCAGCCACCTCAACTTCGCGCA
GAACGAGGCCGATTTCGAGCTGCTGCTCGAACGCATGAACAAGATGCGCGGACCGCGCGAGTTCTTCAGCCGGGCCGCGT
GA

Upstream 100 bases:

>100_bases
AGACCGTGATTCCCGGACGCGGGCCGGCGGAGGACTGGCTTGCCGCAGCGAGCGGGCAGAACGTCGCCCTGCTTCCCCCT
TCCCCTGCCGCCGCTCACGC

Downstream 100 bases:

>100_bases
CATGCCGGTGACGCTCTCGACGCTAAAAGCGCTGCGGCAGAAGGGCGAGAAGATCGCCGTGCTCACGTGCTACGACGCGA
GCTTCGCGCGCGTGTTCGAC

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTSSRYRYIVVEGPIGAGKTSLTHKLAERLGADLLLENAGDNPFLPRFYQEPRRYALPTQLHFLFDRSRQLRDLGQGDLF
RSGTVSDFLIDKDMLFARLNLDDDEFELYQKVYADLAPQAATPDLVIYLQAPTETLHERVRRRGIDFERGMDAAYLERLA
NSYSEFFHRYDAAPLLIVNTSHLNFAQNEADFELLLERMNKMRGPREFFSRAA

Sequences:

>Translated_213_residues
MTSSRYRYIVVEGPIGAGKTSLTHKLAERLGADLLLENAGDNPFLPRFYQEPRRYALPTQLHFLFDRSRQLRDLGQGDLF
RSGTVSDFLIDKDMLFARLNLDDDEFELYQKVYADLAPQAATPDLVIYLQAPTETLHERVRRRGIDFERGMDAAYLERLA
NSYSEFFHRYDAAPLLIVNTSHLNFAQNEADFELLLERMNKMRGPREFFSRAA
>Mature_212_residues
TSSRYRYIVVEGPIGAGKTSLTHKLAERLGADLLLENAGDNPFLPRFYQEPRRYALPTQLHFLFDRSRQLRDLGQGDLFR
SGTVSDFLIDKDMLFARLNLDDDEFELYQKVYADLAPQAATPDLVIYLQAPTETLHERVRRRGIDFERGMDAAYLERLAN
SYSEFFHRYDAAPLLIVNTSHLNFAQNEADFELLLERMNKMRGPREFFSRAA

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24676; Mature: 24545

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSRYRYIVVEGPIGAGKTSLTHKLAERLGADLLLENAGDNPFLPRFYQEPRRYALPTQ
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCHHEEEECCCCCCCCCHHHHCCHHCCCCHH
LHFLFDRSRQLRDLGQGDLFRSGTVSDFLIDKDMLFARLNLDDDEFELYQKVYADLAPQA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCC
ATPDLVIYLQAPTETLHERVRRRGIDFERGMDAAYLERLANSYSEFFHRYDAAPLLIVNT
CCCCEEEEEECCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SHLNFAQNEADFELLLERMNKMRGPREFFSRAA
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure 
TSSRYRYIVVEGPIGAGKTSLTHKLAERLGADLLLENAGDNPFLPRFYQEPRRYALPTQ
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCHHEEEECCCCCCCCCHHHHCCHHCCCCHH
LHFLFDRSRQLRDLGQGDLFRSGTVSDFLIDKDMLFARLNLDDDEFELYQKVYADLAPQA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCC
ATPDLVIYLQAPTETLHERVRRRGIDFERGMDAAYLERLANSYSEFFHRYDAAPLLIVNT
CCCCEEEEEECCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SHLNFAQNEADFELLLERMNKMRGPREFFSRAA
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]