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The map label for this gene is dnaJ [H]

Identifier: 74318017

GI number: 74318017

Start: 2087562

End: 2088746

Strand: Reverse

Name: dnaJ [H]

Synonym: Tbd_1999

Alternate gene names: 74318017

Gene position: 2088746-2087562 (Counterclockwise)

Preceding gene: 74318019

Following gene: 74318012

Centisome position: 71.78

GC content: 66.5

Gene sequence:

>1185_bases
ATGCAGGACATGGACGCAACCTACACCCATTACGAACGCCTTGCCGTTTCCCGCGATGCGCCGCCCGAAGTGATACGCGC
GGCCTACAAGGCGCTCAGCCAGAAATACCATCCGGACAAGAATCCGGGCGACAGCGAAGCCGCGCGCGTCATGACGCTGT
TGAATCAGTCCTATGACGTGCTGATGGATCCGGTGCGCCGGGCCGAGTACGACGCGTCGCTCGACGCGCCGGACGATGCG
GGCGACGAGCCGCCAATCTCCGAGCCTGAAGAAGACAGTCCACGCCTCGCGTTCGTGCTCCCGATCCTAGTGCGTACCCG
GCTCGGTACGCGCGGCGCGCTTCTGCTAGCCTTCGGCGGCGTTTTTGTAATTTCCGCCCTGGTCGGGGGAATTCTTGCAA
AGGCGCAGGAGAAGGAGGACGCGATGGAGGCGCAGTGGGCGGCTCACGTGCGGGAGGATCGCACGACCGTCGCCTCGAAC
GCGCCGCCCCCGGTGTCGGCACTTGCGATGGGCAACGCGCCGGCGTACGAAAGCCCGGCCATCGTGCCCGGCCCGGCTGC
CGAGTCCGCCCGCCCAGAGCCGGAAGAGGAGGTGACACTGGCGATTGCCGACCCGGCCCCGGGCCCGGCGCTGCCGCCCC
CCCTTGAAGCGAAGGACGCACGCGGCGCAACGCTTGCGGCCGAAGAGGCAGGCGTGGAAACCCCGTCTCCGGAAACCGCG
CCCGCGTCCGCGTCCGACAAGCCCGACGCGAAGGCTGACCGTTCTCCCGGCAAGGAGAAGCCCGCCGCCTGTGCCGCGTC
GGAAGGTGACCCCTTCCCGAAAGAGTCCTACAGCGGCTATCTTCCCGGCCAGCCGGCGATGAACGTGAGCGGGCGCTCGA
CATTCACGGTGGACAACATGCATGTCGACGAGGACGTTCTGGTCAAGCTCGTCGACGTCGGCAATCCGACCTTCGCGCGA
AGCTTCCAGGTCAGGGCGAATTCCAGTTTCACCGCCGAACAACTCGGCCACGGCAAGTACAAGGTGCTGTATCGCGCGAG
GAAATCGAACTGCGACTGGCACGCGCTCGGCCGCGTGTTCGACCTTCGCGAGGAGGAAGCGGACGGCGCTGCGCGTCCCA
CGAACGTCAAGGTCACCCTGCACGCGGGCGAAGACATCGCGTCTTCGGAAGCCGAACGAAACTGA

Upstream 100 bases:

>100_bases
ACTTGACACAGCCTCCGACAGAGATCGCGCGCGCAGGCCCGATGCCGAATGGCCGGACGTGGGCCGCGAGTCAAGCGAAC
TGGCCCGGTTTTTGCCCGTC

Downstream 100 bases:

>100_bases
AAGTCGTCCCTGGTGTGTCGCATCGCGCAGCGCGAGCGACGGAAATGAACAATAGCGGCGCAGGCCGCTATGTTTTTTCG
ATGGTGTTTTGTGCCGAGGT

Product: heat shock protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MQDMDATYTHYERLAVSRDAPPEVIRAAYKALSQKYHPDKNPGDSEAARVMTLLNQSYDVLMDPVRRAEYDASLDAPDDA
GDEPPISEPEEDSPRLAFVLPILVRTRLGTRGALLLAFGGVFVISALVGGILAKAQEKEDAMEAQWAAHVREDRTTVASN
APPPVSALAMGNAPAYESPAIVPGPAAESARPEPEEEVTLAIADPAPGPALPPPLEAKDARGATLAAEEAGVETPSPETA
PASASDKPDAKADRSPGKEKPAACAASEGDPFPKESYSGYLPGQPAMNVSGRSTFTVDNMHVDEDVLVKLVDVGNPTFAR
SFQVRANSSFTAEQLGHGKYKVLYRARKSNCDWHALGRVFDLREEEADGAARPTNVKVTLHAGEDIASSEAERN

Sequences:

>Translated_394_residues
MQDMDATYTHYERLAVSRDAPPEVIRAAYKALSQKYHPDKNPGDSEAARVMTLLNQSYDVLMDPVRRAEYDASLDAPDDA
GDEPPISEPEEDSPRLAFVLPILVRTRLGTRGALLLAFGGVFVISALVGGILAKAQEKEDAMEAQWAAHVREDRTTVASN
APPPVSALAMGNAPAYESPAIVPGPAAESARPEPEEEVTLAIADPAPGPALPPPLEAKDARGATLAAEEAGVETPSPETA
PASASDKPDAKADRSPGKEKPAACAASEGDPFPKESYSGYLPGQPAMNVSGRSTFTVDNMHVDEDVLVKLVDVGNPTFAR
SFQVRANSSFTAEQLGHGKYKVLYRARKSNCDWHALGRVFDLREEEADGAARPTNVKVTLHAGEDIASSEAERN
>Mature_394_residues
MQDMDATYTHYERLAVSRDAPPEVIRAAYKALSQKYHPDKNPGDSEAARVMTLLNQSYDVLMDPVRRAEYDASLDAPDDA
GDEPPISEPEEDSPRLAFVLPILVRTRLGTRGALLLAFGGVFVISALVGGILAKAQEKEDAMEAQWAAHVREDRTTVASN
APPPVSALAMGNAPAYESPAIVPGPAAESARPEPEEEVTLAIADPAPGPALPPPLEAKDARGATLAAEEAGVETPSPETA
PASASDKPDAKADRSPGKEKPAACAASEGDPFPKESYSGYLPGQPAMNVSGRSTFTVDNMHVDEDVLVKLVDVGNPTFAR
SFQVRANSSFTAEQLGHGKYKVLYRARKSNCDWHALGRVFDLREEEADGAARPTNVKVTLHAGEDIASSEAERN

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Escherichia coli, GI1786197, Length=66, Percent_Identity=46.969696969697, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 41990; Mature: 41990

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDMDATYTHYERLAVSRDAPPEVIRAAYKALSQKYHPDKNPGDSEAARVMTLLNQSYDV
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHH
LMDPVRRAEYDASLDAPDDAGDEPPISEPEEDSPRLAFVLPILVRTRLGTRGALLLAFGG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHH
VFVISALVGGILAKAQEKEDAMEAQWAAHVREDRTTVASNAPPPVSALAMGNAPAYESPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCC
IVPGPAAESARPEPEEEVTLAIADPAPGPALPPPLEAKDARGATLAAEEAGVETPSPETA
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCC
PASASDKPDAKADRSPGKEKPAACAASEGDPFPKESYSGYLPGQPAMNVSGRSTFTVDNM
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
HVDEDVLVKLVDVGNPTFARSFQVRANSSFTAEQLGHGKYKVLYRARKSNCDWHALGRVF
CCCHHHHEEEECCCCCCCEEEEEEECCCCCCHHHHCCCCEEEEEEHHHCCCCHHHHHHHH
DLREEEADGAARPTNVKVTLHAGEDIASSEAERN
HHHHHHCCCCCCCCEEEEEEECCCCHHCCCCCCC
>Mature Secondary Structure
MQDMDATYTHYERLAVSRDAPPEVIRAAYKALSQKYHPDKNPGDSEAARVMTLLNQSYDV
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHH
LMDPVRRAEYDASLDAPDDAGDEPPISEPEEDSPRLAFVLPILVRTRLGTRGALLLAFGG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHH
VFVISALVGGILAKAQEKEDAMEAQWAAHVREDRTTVASNAPPPVSALAMGNAPAYESPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCC
IVPGPAAESARPEPEEEVTLAIADPAPGPALPPPLEAKDARGATLAAEEAGVETPSPETA
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCCCC
PASASDKPDAKADRSPGKEKPAACAASEGDPFPKESYSGYLPGQPAMNVSGRSTFTVDNM
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
HVDEDVLVKLVDVGNPTFARSFQVRANSSFTAEQLGHGKYKVLYRARKSNCDWHALGRVF
CCCHHHHEEEECCCCCCCEEEEEEECCCCCCHHHHCCCCEEEEEEHHHCCCCHHHHHHHH
DLREEEADGAARPTNVKVTLHAGEDIASSEAERN
HHHHHHCCCCCCCCEEEEEEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]