Click here to switch to the map view.

The map label for this gene is cynS

Identifier: 74317959

GI number: 74317959

Start: 2035124

End: 2035567

Strand: Reverse

Name: cynS

Synonym: Tbd_1941

Alternate gene names: 74317959

Gene position: 2035567-2035124 (Counterclockwise)

Preceding gene: 74317960

Following gene: 74317958

Centisome position: 69.96

GC content: 62.16

Gene sequence:

>444_bases
ATGACACGCGACCAAGTCACCCAACTCGTCCTCGACAGCAAGCGCCGCAAGCAACTCAAATGGGCGCAGCTCGCCGAGGC
GACGGGCCAGAGCAAGGAATGGACCGCGGCCGCGCTGCTCGGGCAGATGACGCTGAGCGCCGCGCAAGCGGGCGCCGTCG
GCCGCCTGCTCGATCTGCCGGCCGACGCGGTCGACGGGCTGCAGGTCGTGCCGTACAAGGGATCCTTGCCGACCGCCGTG
CCGACCGATCCGTTGATCTACCGCTTTTACGAGTTGATCAACGTCTATGGCACGAGCATCAAGGAATTGATCCACGAGGA
ATTCGGCGACGGCATCATGAGTGCGATCGATTTCTCGATGGACATCTCGCGCGAGGCTGACCCCAAAGGCGATCGTGTAC
GTATCGTCCTGAACGGCAAGTTCCTGCCCTACAGAATGTACTGA

Upstream 100 bases:

>100_bases
CGGCCTTGCATGCCACCCGGTTGCCCGCCACGTCGGCAGAGCCGTCGGCTGAGCGCGGCGCCGCATTCGTTTCCTCCCAA
CCCAGCGAAAGGAGATCGCG

Downstream 100 bases:

>100_bases
GTTTGGCGTGCGTTGCAGCGGTTCGGCGAGTGTTCGCGGAGCCGCTGCCGTCGCGTTCCCGGATCACGGGACGCCCGGTC
GACGGCGCGCCTCGCCCTTT

Product: cyanate hydratase

Products: NA

Alternate protein names: Cyanase; Cyanate hydrolase; Cyanate lyase

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MTRDQVTQLVLDSKRRKQLKWAQLAEATGQSKEWTAAALLGQMTLSAAQAGAVGRLLDLPADAVDGLQVVPYKGSLPTAV
PTDPLIYRFYELINVYGTSIKELIHEEFGDGIMSAIDFSMDISREADPKGDRVRIVLNGKFLPYRMY

Sequences:

>Translated_147_residues
MTRDQVTQLVLDSKRRKQLKWAQLAEATGQSKEWTAAALLGQMTLSAAQAGAVGRLLDLPADAVDGLQVVPYKGSLPTAV
PTDPLIYRFYELINVYGTSIKELIHEEFGDGIMSAIDFSMDISREADPKGDRVRIVLNGKFLPYRMY
>Mature_146_residues
TRDQVTQLVLDSKRRKQLKWAQLAEATGQSKEWTAAALLGQMTLSAAQAGAVGRLLDLPADAVDGLQVVPYKGSLPTAVP
TDPLIYRFYELINVYGTSIKELIHEEFGDGIMSAIDFSMDISREADPKGDRVRIVLNGKFLPYRMY

Specific function: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide

COG id: COG1513

COG function: function code P; Cyanate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyanase family

Homologues:

Organism=Escherichia coli, GI1786535, Length=139, Percent_Identity=47.4820143884892, Blast_Score=140, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYNS_THIDA (Q3SHJ2)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315699.1
- HSSP:   P00816
- ProteinModelPortal:   Q3SHJ2
- SMR:   Q3SHJ2
- STRING:   Q3SHJ2
- GeneID:   3674051
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1941
- NMPDR:   fig|292415.3.peg.2039
- eggNOG:   COG1513
- HOGENOM:   HBG317643
- OMA:   SAIDFDM
- ProtClustDB:   PRK02866
- BioCyc:   TDEN292415:TBD_1941-MONOMER
- HAMAP:   MF_00535
- InterPro:   IPR008076
- InterPro:   IPR003712
- InterPro:   IPR010982
- Gene3D:   G3DSA:3.30.1160.10
- PIRSF:   PIRSF001263
- PRINTS:   PR01693
- TIGRFAMs:   TIGR00673

Pfam domain/function: PF02560 Cyanate_lyase; SSF55234 Cyanate_lyase_C; SSF47413 Lambda_like_DNA

EC number: =4.2.1.104

Molecular weight: Translated: 16305; Mature: 16174

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: ACT_SITE 88-88 ACT_SITE 91-91 ACT_SITE 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDQVTQLVLDSKRRKQLKWAQLAEATGQSKEWTAAALLGQMTLSAAQAGAVGRLLDLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCC
ADAVDGLQVVPYKGSLPTAVPTDPLIYRFYELINVYGTSIKELIHEEFGDGIMSAIDFSM
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHCC
DISREADPKGDRVRIVLNGKFLPYRMY
CCCCCCCCCCCEEEEEECCCCCEEECC
>Mature Secondary Structure 
TRDQVTQLVLDSKRRKQLKWAQLAEATGQSKEWTAAALLGQMTLSAAQAGAVGRLLDLP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCC
ADAVDGLQVVPYKGSLPTAVPTDPLIYRFYELINVYGTSIKELIHEEFGDGIMSAIDFSM
CCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHCC
DISREADPKGDRVRIVLNGKFLPYRMY
CCCCCCCCCCCEEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA