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The map label for this gene is orn

Identifier: 74317857

GI number: 74317857

Start: 1937558

End: 1938106

Strand: Reverse

Name: orn

Synonym: Tbd_1839

Alternate gene names: 74317857

Gene position: 1938106-1937558 (Counterclockwise)

Preceding gene: 74317862

Following gene: 74317854

Centisome position: 66.61

GC content: 63.02

Gene sequence:

>549_bases
ATGGCGCTCAACCCCACGCATCTGCTCTGGCTCGACATGGAAATGACCGGCCTGTCGCCCGAGAGCGACCGCATCATCGA
ACTTGCGATCGTCGTGACCGACGCCGACCTCAATACCGTCGCCGAGGGGCCGGTGCTGGTCGTGCATCAGCCCGACGCGG
TGATGGACGCGATGGACAGCTGGAACAGGGGCACCCACGGCAAGTCGGGGCTGATCGATCGCGTCAAGGCGTCGCAGCTC
AGCGAGTCCGATGCCGAGGCGCAGATGCTCGAATTCGTCAAACAGCACGTCTCACCGCGGACCTCGCCGATGTGCGGCAA
CTCGATCTGTCAGGATCGGCGCTTCATGGCGCGCCACATGCCCGAGCTCGAAGCCTTCTTCCACTATCGCAACCTCGACG
TCAGCACGCTCAAGGAGCTCGCCAAGCGCTGGCGCCCGGGCCTCTGCGACGCGTTCAAGAAATCGAACAAGCACGAGGCG
CTTGCCGACATCTACGAATCCATCGACGAGCTCAGGTACTACCGCGAGCACTTCATTCGCGCCGAGTAA

Upstream 100 bases:

>100_bases
TGGGATAGGCTCCGATTATGGCTTCAAGCCGGGCCTTCCGCTACCCCGCGCAGGGCAGGGTCTATGCGAGAATGCCGGCT
ATCCCATTCAGGAAATCGTC

Downstream 100 bases:

>100_bases
AAAAGCGGCCCGAGGCCGCCGCAGGAGGAAGACGGGGTCGCCGGTCAGAAGAACCAGGTCAGCTGCACGCTGGCGCGGTC
GCCCAGGTTGTCTGCGATCG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MALNPTHLLWLDMEMTGLSPESDRIIELAIVVTDADLNTVAEGPVLVVHQPDAVMDAMDSWNRGTHGKSGLIDRVKASQL
SESDAEAQMLEFVKQHVSPRTSPMCGNSICQDRRFMARHMPELEAFFHYRNLDVSTLKELAKRWRPGLCDAFKKSNKHEA
LADIYESIDELRYYREHFIRAE

Sequences:

>Translated_182_residues
MALNPTHLLWLDMEMTGLSPESDRIIELAIVVTDADLNTVAEGPVLVVHQPDAVMDAMDSWNRGTHGKSGLIDRVKASQL
SESDAEAQMLEFVKQHVSPRTSPMCGNSICQDRRFMARHMPELEAFFHYRNLDVSTLKELAKRWRPGLCDAFKKSNKHEA
LADIYESIDELRYYREHFIRAE
>Mature_181_residues
ALNPTHLLWLDMEMTGLSPESDRIIELAIVVTDADLNTVAEGPVLVVHQPDAVMDAMDSWNRGTHGKSGLIDRVKASQLS
ESDAEAQMLEFVKQHVSPRTSPMCGNSICQDRRFMARHMPELEAFFHYRNLDVSTLKELAKRWRPGLCDAFKKSNKHEAL
ADIYESIDELRYYREHFIRAE

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=173, Percent_Identity=46.8208092485549, Blast_Score=174, Evalue=3e-44,
Organism=Escherichia coli, GI87082382, Length=180, Percent_Identity=59.4444444444444, Blast_Score=234, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17557752, Length=175, Percent_Identity=46.2857142857143, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323088, Length=182, Percent_Identity=36.2637362637363, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=44.8863636363636, Blast_Score=170, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_THIDA (Q3SHU1)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315597.1
- HSSP:   P0A784
- ProteinModelPortal:   Q3SHU1
- SMR:   Q3SHU1
- STRING:   Q3SHU1
- GeneID:   3671504
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1839
- NMPDR:   fig|292415.3.peg.1935
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   Q3SHU1
- ProtClustDB:   PRK05359
- BioCyc:   TDEN292415:TBD_1839-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20815; Mature: 20684

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNPTHLLWLDMEMTGLSPESDRIIELAIVVTDADLNTVAEGPVLVVHQPDAVMDAMDS
CCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEECCCCCHHCCCCEEEEECCHHHHHHHHH
WNRGTHGKSGLIDRVKASQLSESDAEAQMLEFVKQHVSPRTSPMCGNSICQDRRFMARHM
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
PELEAFFHYRNLDVSTLKELAKRWRPGLCDAFKKSNKHEALADIYESIDELRYYREHFIR
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AE
CC
>Mature Secondary Structure 
ALNPTHLLWLDMEMTGLSPESDRIIELAIVVTDADLNTVAEGPVLVVHQPDAVMDAMDS
CCCCCEEEEEEEEECCCCCCCCCEEEEEEEEECCCCCHHCCCCEEEEECCHHHHHHHHH
WNRGTHGKSGLIDRVKASQLSESDAEAQMLEFVKQHVSPRTSPMCGNSICQDRRFMARHM
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
PELEAFFHYRNLDVSTLKELAKRWRPGLCDAFKKSNKHEALADIYESIDELRYYREHFIR
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
AE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA