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The map label for this gene is rmlC [H]

Identifier: 74317796

GI number: 74317796

Start: 1877813

End: 1878355

Strand: Reverse

Name: rmlC [H]

Synonym: Tbd_1778

Alternate gene names: 74317796

Gene position: 1878355-1877813 (Counterclockwise)

Preceding gene: 74317797

Following gene: 74317795

Centisome position: 64.55

GC content: 62.25

Gene sequence:

>543_bases
ATGAACGTCGTCAAGACCTCGCTTCCGGAAGTCCTCTTGCTCGAGCCCAAGGTCTTCGGCGACGCCCGTGGCTTCTTTCT
CGAGAGCTGGAATCGCAAGACGTTTTCCGCGCTGGGCCTGGACGTCGACTTCGTGCAGGACAACCATTCGCGGTCGGCGC
GCGGCGTGCTGCGCGGCCTGCATTACCAGATCAAGGATCCGCAGGGCAAGCTCGTGCGTGTCGTGAACGGCTCGGTTTTC
GACGTCGCGGTCGATCTGAGGCGCGCGTCGCCGAATTTCGGCCGCTGGGTGGGTTACGAGCTGTCGGCCGAAAATCAGAG
AATGCTGTGGATTCCGCCCGGCTTCGCCCATGGCTTTCTGGTGTTGTCCGAGAGCGCAGACTTTCTTTACAAGACGACCG
CGTATTACGCGCCTGAGTGGGACCGGGGCGTGTGCTGGAACGATCCCGAAATCGGCATCGAGTGGCCATGGAGCGGCTCG
CCGACCCTCTCGGCCAAGGACCAGGTCTTGCCCTTTCTCAAGGACGCCGAGGTCTACGCGTGA

Upstream 100 bases:

>100_bases
GAAGAAGAACGGCTACGGAAGGTACCTGCTGGAAATTCTGGACGAGCATGTCTTCTAGCGTGTGCCCCCACTCCGTTTCA
TCCGTCCTCGGGAGAGCGGC

Downstream 100 bases:

>100_bases
GGCCGCGCATTCTGCTCACCGGGCCGAACGGCCAGGTCGGCTGGGAGTTGCAGCGCACGCTGGGCTCCCTCGGCGAGGTC
GTCGCCCTCGATTCGAGCGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNVVKTSLPEVLLLEPKVFGDARGFFLESWNRKTFSALGLDVDFVQDNHSRSARGVLRGLHYQIKDPQGKLVRVVNGSVF
DVAVDLRRASPNFGRWVGYELSAENQRMLWIPPGFAHGFLVLSESADFLYKTTAYYAPEWDRGVCWNDPEIGIEWPWSGS
PTLSAKDQVLPFLKDAEVYA

Sequences:

>Translated_180_residues
MNVVKTSLPEVLLLEPKVFGDARGFFLESWNRKTFSALGLDVDFVQDNHSRSARGVLRGLHYQIKDPQGKLVRVVNGSVF
DVAVDLRRASPNFGRWVGYELSAENQRMLWIPPGFAHGFLVLSESADFLYKTTAYYAPEWDRGVCWNDPEIGIEWPWSGS
PTLSAKDQVLPFLKDAEVYA
>Mature_180_residues
MNVVKTSLPEVLLLEPKVFGDARGFFLESWNRKTFSALGLDVDFVQDNHSRSARGVLRGLHYQIKDPQGKLVRVVNGSVF
DVAVDLRRASPNFGRWVGYELSAENQRMLWIPPGFAHGFLVLSESADFLYKTTAYYAPEWDRGVCWNDPEIGIEWPWSGS
PTLSAKDQVLPFLKDAEVYA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=172, Percent_Identity=59.8837209302326, Blast_Score=210, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17550412, Length=155, Percent_Identity=48.3870967741936, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20367; Mature: 20367

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVKTSLPEVLLLEPKVFGDARGFFLESWNRKTFSALGLDVDFVQDNHSRSARGVLRGL
CCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCEEEECCCEEEEECCCCCCHHHHHHHCC
HYQIKDPQGKLVRVVNGSVFDVAVDLRRASPNFGRWVGYELSAENQRMLWIPPGFAHGFL
EEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCEEE
VLSESADFLYKTTAYYAPEWDRGVCWNDPEIGIEWPWSGSPTLSAKDQVLPFLKDAEVYA
EEECCCCEEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVVKTSLPEVLLLEPKVFGDARGFFLESWNRKTFSALGLDVDFVQDNHSRSARGVLRGL
CCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCEEEECCCEEEEECCCCCCHHHHHHHCC
HYQIKDPQGKLVRVVNGSVFDVAVDLRRASPNFGRWVGYELSAENQRMLWIPPGFAHGFL
EEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCEEE
VLSESADFLYKTTAYYAPEWDRGVCWNDPEIGIEWPWSGSPTLSAKDQVLPFLKDAEVYA
EEECCCCEEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]