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The map label for this gene is zupT [H]

Identifier: 74317783

GI number: 74317783

Start: 1858439

End: 1859224

Strand: Reverse

Name: zupT [H]

Synonym: Tbd_1765

Alternate gene names: 74317783

Gene position: 1859224-1858439 (Counterclockwise)

Preceding gene: 74317784

Following gene: 74317782

Centisome position: 63.9

GC content: 62.47

Gene sequence:

>786_bases
ATGTCCACCCTCGCCGTCATTCTGCTCGCAACTGCCGCCGGCAGTCTGCTGAGCTTCCTGCTTGCCGGCGCATTGGCATT
GTCGGCGCGTCCGAGCTGGATTCCGGTACTCGTGAGCTACGCGATCGGCGCATTGCTCGGCGCTTCGCTGCTCGAGGTCC
TGCCAGAGGCGGTTGAAATCGGCGGCGACATCGAAACGGTGGCGAAGGCCTTGCTCGGTGGCATCCTGCTGTTCTTTCTG
CTCGAGAAGCTCGTGTTGTGGCGACATTGCCACGAGGAAATTTGCGAAGCGCACGGCGGGAATTCCCGCCCGGCCCACGG
CCATGATCACGGCCGATCCGGCCTGATGATCACAGTGGGCGACACGTTTCATAATTTTGTAGATGGCGTCATCATCGCGG
GCGCCTTCCTCGCCGACTTCCGCCTCGGCGTCGTCACGGCACTTGCGATCATCGCGCACGAAATTCCGCAGGAGATCGGG
GACTTCCTGATATTGCTGCATTCCGGTTACAGCCGCGGGCGCGCCCTGCTGCTGAATTTCGTCACGGGCGTGGCGACGCT
GGTCGGCGCCCTCGTGGGTTATTACGCGCTCTCGATGCTCGAAGGATGGACGCCGGTATTGCTGGGACTCGCCGGCGCGA
GCATGCTATACGTCGCGCTGTCCGACCTGATTCCGGGCTTGCACAAGCGCGCGGAAATCGGCGCGACGCTGCAGCAACTC
GCTTTAATCGGTCTCGGGATCGGTAGCGTTGCGCTGGTCGGCTACCTGATCGGACACGGTCATTGA

Upstream 100 bases:

>100_bases
CCGCTTCTCGGAGCGAGCGCCGTTCGGGTTCGTACACCCCGCTCGCTGCGGAGCGAAGGTCCCCCGGTATAATCCCTCGC
TTTCTTGCTGCCGGGTTCAC

Downstream 100 bases:

>100_bases
ACGGACCCGCCGCTTGCGTCCTCCGACGACGTAGACGAACAGCGCAATCGGCAACGCGCCGAGGAAGACCAGGATGGCCA
GCGCCTTGCCGACGCTGCTC

Product: ZIP Zinc transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSTLAVILLATAAGSLLSFLLAGALALSARPSWIPVLVSYAIGALLGASLLEVLPEAVEIGGDIETVAKALLGGILLFFL
LEKLVLWRHCHEEICEAHGGNSRPAHGHDHGRSGLMITVGDTFHNFVDGVIIAGAFLADFRLGVVTALAIIAHEIPQEIG
DFLILLHSGYSRGRALLLNFVTGVATLVGALVGYYALSMLEGWTPVLLGLAGASMLYVALSDLIPGLHKRAEIGATLQQL
ALIGLGIGSVALVGYLIGHGH

Sequences:

>Translated_261_residues
MSTLAVILLATAAGSLLSFLLAGALALSARPSWIPVLVSYAIGALLGASLLEVLPEAVEIGGDIETVAKALLGGILLFFL
LEKLVLWRHCHEEICEAHGGNSRPAHGHDHGRSGLMITVGDTFHNFVDGVIIAGAFLADFRLGVVTALAIIAHEIPQEIG
DFLILLHSGYSRGRALLLNFVTGVATLVGALVGYYALSMLEGWTPVLLGLAGASMLYVALSDLIPGLHKRAEIGATLQQL
ALIGLGIGSVALVGYLIGHGH
>Mature_260_residues
STLAVILLATAAGSLLSFLLAGALALSARPSWIPVLVSYAIGALLGASLLEVLPEAVEIGGDIETVAKALLGGILLFFLL
EKLVLWRHCHEEICEAHGGNSRPAHGHDHGRSGLMITVGDTFHNFVDGVIIAGAFLADFRLGVVTALAIIAHEIPQEIGD
FLILLHSGYSRGRALLLNFVTGVATLVGALVGYYALSMLEGWTPVLLGLAGASMLYVALSDLIPGLHKRAEIGATLQQLA
LIGLGIGSVALVGYLIGHGH

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI187936949, Length=149, Percent_Identity=32.2147651006711, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI55741750, Length=149, Percent_Identity=32.2147651006711, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI223633937, Length=256, Percent_Identity=31.25, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI223633939, Length=116, Percent_Identity=37.0689655172414, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI40255101, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI190358541, Length=125, Percent_Identity=36, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI205830424, Length=125, Percent_Identity=36, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI190360568, Length=125, Percent_Identity=36, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI190014617, Length=255, Percent_Identity=28.6274509803922, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI205830407, Length=115, Percent_Identity=36.5217391304348, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI24586665, Length=115, Percent_Identity=36.5217391304348, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI205830403, Length=115, Percent_Identity=36.5217391304348, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI205830405, Length=115, Percent_Identity=36.5217391304348, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI205830426, Length=117, Percent_Identity=37.6068376068376, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI115430259, Length=119, Percent_Identity=41.1764705882353, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI115430255, Length=114, Percent_Identity=41.2280701754386, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI153252201, Length=123, Percent_Identity=36.5853658536585, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI206597541, Length=135, Percent_Identity=41.4814814814815, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI206597539, Length=135, Percent_Identity=41.4814814814815, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI117553619, Length=256, Percent_Identity=25.78125, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI117553608, Length=256, Percent_Identity=25.78125, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI153252214, Length=115, Percent_Identity=35.6521739130435, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193209531, Length=255, Percent_Identity=28.6274509803922, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71992548, Length=293, Percent_Identity=25.2559726962457, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994730, Length=305, Percent_Identity=24.5901639344262, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998183, Length=153, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538884, Length=110, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322166, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24651189, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24651193, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24651187, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24651191, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24651195, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24651197, Length=279, Percent_Identity=30.4659498207885, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI161083817, Length=114, Percent_Identity=38.5964912280702, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24664383, Length=114, Percent_Identity=38.5964912280702, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45549201, Length=125, Percent_Identity=36, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17864610, Length=129, Percent_Identity=34.1085271317829, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 27159; Mature: 27028

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLAVILLATAAGSLLSFLLAGALALSARPSWIPVLVSYAIGALLGASLLEVLPEAVEI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGDIETVAKALLGGILLFFLLEKLVLWRHCHEEICEAHGGNSRPAHGHDHGRSGLMITVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
DTFHNFVDGVIIAGAFLADFRLGVVTALAIIAHEIPQEIGDFLILLHSGYSRGRALLLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VTGVATLVGALVGYYALSMLEGWTPVLLGLAGASMLYVALSDLIPGLHKRAEIGATLQQL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIGLGIGSVALVGYLIGHGH
HHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STLAVILLATAAGSLLSFLLAGALALSARPSWIPVLVSYAIGALLGASLLEVLPEAVEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGDIETVAKALLGGILLFFLLEKLVLWRHCHEEICEAHGGNSRPAHGHDHGRSGLMITVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
DTFHNFVDGVIIAGAFLADFRLGVVTALAIIAHEIPQEIGDFLILLHSGYSRGRALLLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VTGVATLVGALVGYYALSMLEGWTPVLLGLAGASMLYVALSDLIPGLHKRAEIGATLQQL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIGLGIGSVALVGYLIGHGH
HHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA