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The map label for this gene is hitA [H]

Identifier: 74317723

GI number: 74317723

Start: 1795496

End: 1795834

Strand: Reverse

Name: hitA [H]

Synonym: Tbd_1705

Alternate gene names: 74317723

Gene position: 1795834-1795496 (Counterclockwise)

Preceding gene: 74317724

Following gene: 74317722

Centisome position: 61.72

GC content: 61.36

Gene sequence:

>339_bases
ATGAGTGACTGCATCTTCTGCAAGATCGTCCGAGGCGAACTGCCCGCCAGCAAGGTCTATGAAGACGAGGAATTACTCGC
CTTCCACGACATCCATCCGTTTGCGCGCGTGCATCTGCTGATCATTCCCAAGCTGCATGTCGCGTCGCTGGCCGACTGCA
CGGTCGCGCACCAGGACCTGCTCGGCAAGATGCTGCTGCTGGCCCCGCGTTTGGCGAAGGAATCGGGGCTCGACGCCGGT
TTCAAGACCCTCATCAATACCGGCCGCGGAGGCGGCCAGGAAGTATTCCACATTCACGTACACGTGTTCGGCGGCGGCGA
TCCCGCCAAGCGCGCTTGA

Upstream 100 bases:

>100_bases
CGCACAAGGGCCTCAAGCCGGCGGACGTGCTCGAGGAACTGGCGCGCCGCGAGGGGCTTTCGGGGCTGACGGAAAAAGCG
AACCGGCAAGGTGGATCGAC

Downstream 100 bases:

>100_bases
GTAAAGGAGATATCGCATGGGCAGCTTCAGCATCTGGCATTGGCTGATCGTTCTGGTCGTGGTGTTGCTGATTTTCGGCA
CCAAGAAACTGCGCAACATC

Product: HIT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 112; Mature: 111

Protein sequence:

>112_residues
MSDCIFCKIVRGELPASKVYEDEELLAFHDIHPFARVHLLIIPKLHVASLADCTVAHQDLLGKMLLLAPRLAKESGLDAG
FKTLINTGRGGGQEVFHIHVHVFGGGDPAKRA

Sequences:

>Translated_112_residues
MSDCIFCKIVRGELPASKVYEDEELLAFHDIHPFARVHLLIIPKLHVASLADCTVAHQDLLGKMLLLAPRLAKESGLDAG
FKTLINTGRGGGQEVFHIHVHVFGGGDPAKRA
>Mature_111_residues
SDCIFCKIVRGELPASKVYEDEELLAFHDIHPFARVHLLIIPKLHVASLADCTVAHQDLLGKMLLLAPRLAKESGLDAGF
KTLINTGRGGGQEVFHIHVHVFGGGDPAKRA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=103, Percent_Identity=42.7184466019417, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI14211923, Length=104, Percent_Identity=42.3076923076923, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787346, Length=105, Percent_Identity=41.9047619047619, Blast_Score=91, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17506713, Length=104, Percent_Identity=42.3076923076923, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320078, Length=104, Percent_Identity=42.3076923076923, Blast_Score=76, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574010, Length=103, Percent_Identity=42.7184466019417, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24581222, Length=104, Percent_Identity=42.3076923076923, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 12191; Mature: 12060

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDCIFCKIVRGELPASKVYEDEELLAFHDIHPFARVHLLIIPKLHVASLADCTVAHQDL
CCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
LGKMLLLAPRLAKESGLDAGFKTLINTGRGGGQEVFHIHVHVFGGGDPAKRA
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
SDCIFCKIVRGELPASKVYEDEELLAFHDIHPFARVHLLIIPKLHVASLADCTVAHQDL
CCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
LGKMLLLAPRLAKESGLDAGFKTLINTGRGGGQEVFHIHVHVFGGGDPAKRA
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA