Click here to switch to the map view.

The map label for this gene is ppa [H]

Identifier: 74317670

GI number: 74317670

Start: 1735731

End: 1736351

Strand: Reverse

Name: ppa [H]

Synonym: Tbd_1652

Alternate gene names: 74317670

Gene position: 1736351-1735731 (Counterclockwise)

Preceding gene: 74317671

Following gene: 74317669

Centisome position: 59.67

GC content: 63.12

Gene sequence:

>621_bases
GTGATTCGATCGCAGCCGGTAGCAGCGCGGGGGTATAATGCGCGGCTTTCCGTTTTTCCTACTGAGACCCCCATGAGCCT
CGATCGCGTTAGCTCCGGCCGCAACCTTCCGGACGATTTCAACGTCATCGTCGAGATCCCCGCCCACGGCGAACCCATCA
AGTACGAAGTCGACAAGGAATCCGGCGCGATGTTCGTCGATCGCTTCATGTCGACGGCCATGCACTACCCCTGCAACTAC
GGCTACATCCCGCACACCCTGTCGGAGGACGGCGATCCGGTCGACGTCCTCGTCATCACGCCGATTCCGCTGATCACCGG
CGTGGTCGTGCGCTGCCGCCCGATCGGCATGCTGAAGATGACCGACGAAGCCGGCGTCGACGCCAAGCTGCTGGCGGTCC
CGGTGGAGAAGCTGTGCGGGCTGTACAAGGGTGTCAACAGGCCGGAAGACCTCCAGCCGCTGCTGCTGAAGCAGATCGCC
CATTTCTTCGAGCACTACAAGGACCTCGAAGACGGCAAGTGGGTCAAGGTCGAAGGCTGGACCGGCGTCGACGATGCGCG
CGCCGAGATTCTCGCCGGCGTCGAGCGCTACCGGAACGCGGCGGACAAACCCGCGTTCTAG

Upstream 100 bases:

>100_bases
CGGGCAGTTGACCCCCTGAGCCACCGCGCCTCAGTATCCGCGGGCGAGAGCTTTCCTGTTGTCCGCACCGCTTTCCGCCG
CAGCGCGTCGCAACGGTCCG

Downstream 100 bases:

>100_bases
GGGATAGGGGATAGGGGATAGGATCTAGGAATTAGGGGATCTTGTGCTTCGCCGCATTTCCATGAATTCATAAGGCGCGG
CGAAAGCCGCCCAAAATCCG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIRSQPVAARGYNARLSVFPTETPMSLDRVSSGRNLPDDFNVIVEIPAHGEPIKYEVDKESGAMFVDRFMSTAMHYPCNY
GYIPHTLSEDGDPVDVLVITPIPLITGVVVRCRPIGMLKMTDEAGVDAKLLAVPVEKLCGLYKGVNRPEDLQPLLLKQIA
HFFEHYKDLEDGKWVKVEGWTGVDDARAEILAGVERYRNAADKPAF

Sequences:

>Translated_206_residues
MIRSQPVAARGYNARLSVFPTETPMSLDRVSSGRNLPDDFNVIVEIPAHGEPIKYEVDKESGAMFVDRFMSTAMHYPCNY
GYIPHTLSEDGDPVDVLVITPIPLITGVVVRCRPIGMLKMTDEAGVDAKLLAVPVEKLCGLYKGVNRPEDLQPLLLKQIA
HFFEHYKDLEDGKWVKVEGWTGVDDARAEILAGVERYRNAADKPAF
>Mature_206_residues
MIRSQPVAARGYNARLSVFPTETPMSLDRVSSGRNLPDDFNVIVEIPAHGEPIKYEVDKESGAMFVDRFMSTAMHYPCNY
GYIPHTLSEDGDPVDVLVITPIPLITGVVVRCRPIGMLKMTDEAGVDAKLLAVPVEKLCGLYKGVNRPEDLQPLLLKQIA
HFFEHYKDLEDGKWVKVEGWTGVDDARAEILAGVERYRNAADKPAF

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=175, Percent_Identity=67.4285714285714, Blast_Score=243, Evalue=5e-66,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 22945; Mature: 22945

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSQPVAARGYNARLSVFPTETPMSLDRVSSGRNLPDDFNVIVEIPAHGEPIKYEVDKE
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCC
SGAMFVDRFMSTAMHYPCNYGYIPHTLSEDGDPVDVLVITPIPLITGVVVRCRPIGMLKM
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEE
TDEAGVDAKLLAVPVEKLCGLYKGVNRPEDLQPLLLKQIAHFFEHYKDLEDGKWVKVEGW
CCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
TGVDDARAEILAGVERYRNAADKPAF
CCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIRSQPVAARGYNARLSVFPTETPMSLDRVSSGRNLPDDFNVIVEIPAHGEPIKYEVDKE
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCC
SGAMFVDRFMSTAMHYPCNYGYIPHTLSEDGDPVDVLVITPIPLITGVVVRCRPIGMLKM
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEE
TDEAGVDAKLLAVPVEKLCGLYKGVNRPEDLQPLLLKQIAHFFEHYKDLEDGKWVKVEGW
CCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
TGVDDARAEILAGVERYRNAADKPAF
CCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9423859 [H]