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The map label for this gene is phoP [H]

Identifier: 74317643

GI number: 74317643

Start: 1711923

End: 1712285

Strand: Reverse

Name: phoP [H]

Synonym: Tbd_1625

Alternate gene names: 74317643

Gene position: 1712285-1711923 (Counterclockwise)

Preceding gene: 74317644

Following gene: 74317642

Centisome position: 58.85

GC content: 62.81

Gene sequence:

>363_bases
ATGAAAACAATACTTGCAGTAGACGACTCGGGGTCGCTGCGTCAGATGCTGTCCTTCAGTCTGAAGGCGGCCGGCTACGG
CGTGATCGAGGCCGTCGACGGCGAGGACGGCCTGAAGAAGGCGAAGCAGCAGAAGGTCGACCTGGTCCTCACCGACCAGA
ACATGCCCGGCATGGACGGCCTGACCCTGATCAAGGCGCTACGCGGCATGGCGAACTACAAGAGCGTGCCGATCCTGATG
CTGACGACCGAATCGGGCGACGACATCAAGGCGATGGGGCGTGCCGCGGGCGCGAACGGCTGGCTGGTCAAGCCCTTCGA
TCCGGCGCGCCTGACCGAAGTGGTGAAGAAACTGATCGGCTGA

Upstream 100 bases:

>100_bases
AGCGTAAAACAGCGCCACATGGAAAGCGGCGACATCGACCTTTTTTGAGCTTATGAACCGTCGCGCATGCGCGGCAAAGA
ACGCAGCAGGAGCAATAAGG

Downstream 100 bases:

>100_bases
CGCGACGAACGCGCAGCCCTCGAGAGAACGAAAGACGGAGTCCCAGATGACTATTGATATGAGCCAGTTCTACCAGGTCT
TTTTCGACGAGGCCGACGAG

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MKTILAVDDSGSLRQMLSFSLKAAGYGVIEAVDGEDGLKKAKQQKVDLVLTDQNMPGMDGLTLIKALRGMANYKSVPILM
LTTESGDDIKAMGRAAGANGWLVKPFDPARLTEVVKKLIG

Sequences:

>Translated_120_residues
MKTILAVDDSGSLRQMLSFSLKAAGYGVIEAVDGEDGLKKAKQQKVDLVLTDQNMPGMDGLTLIKALRGMANYKSVPILM
LTTESGDDIKAMGRAAGANGWLVKPFDPARLTEVVKKLIG
>Mature_120_residues
MKTILAVDDSGSLRQMLSFSLKAAGYGVIEAVDGEDGLKKAKQQKVDLVLTDQNMPGMDGLTLIKALRGMANYKSVPILM
LTTESGDDIKAMGRAAGANGWLVKPFDPARLTEVVKKLIG

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=38.4615384615385, Blast_Score=79, Evalue=6e-17,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=29.6610169491525, Blast_Score=76, Evalue=6e-16,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=35.042735042735, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1788394, Length=116, Percent_Identity=32.7586206896552, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=114, Percent_Identity=36.8421052631579, Blast_Score=66, Evalue=7e-13,
Organism=Escherichia coli, GI1788713, Length=104, Percent_Identity=39.4230769230769, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1786911, Length=106, Percent_Identity=33.9622641509434, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=31.0344827586207, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=30.5084745762712, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=31.6239316239316, Blast_Score=59, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 12809; Mature: 12809

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTILAVDDSGSLRQMLSFSLKAAGYGVIEAVDGEDGLKKAKQQKVDLVLTDQNMPGMDG
CCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCH
LTLIKALRGMANYKSVPILMLTTESGDDIKAMGRAAGANGWLVKPFDPARLTEVVKKLIG
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKTILAVDDSGSLRQMLSFSLKAAGYGVIEAVDGEDGLKKAKQQKVDLVLTDQNMPGMDG
CCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCH
LTLIKALRGMANYKSVPILMLTTESGDDIKAMGRAAGANGWLVKPFDPARLTEVVKKLIG
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]