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The map label for this gene is cheA [H]

Identifier: 74317642

GI number: 74317642

Start: 1709801

End: 1711876

Strand: Reverse

Name: cheA [H]

Synonym: Tbd_1624

Alternate gene names: 74317642

Gene position: 1711876-1709801 (Counterclockwise)

Preceding gene: 74317643

Following gene: 74317641

Centisome position: 58.83

GC content: 64.69

Gene sequence:

>2076_bases
ATGACTATTGATATGAGCCAGTTCTACCAGGTCTTTTTCGACGAGGCCGACGAGCTCCTCGCCGAAATGGAGAAGCTGCT
GCTGGCTCTGGACGTGGCGGCACCCGACAGCGAGGACCTCAACGCGATCTTCCGCGCCGCGCATTCGATCAAGGGCGGCG
CCGCGACCTTCGGCTTCACCGACATCACCGAAGTCACCCACATGCTCGAGTCCCTGCTCGACCGCATTCGCAAGGGCGAA
ATGGCGCTGACCGGAGAGCACGTCGACGCCTTTCTGGTGGCGAAAGACATCCTCGCGATGCAGATGGAAGGCCATCACCA
CGGCGCGGGCGTCGACCAGTCGTCGGTCGATTCGGTTTGCCAGCGGCTGAAGGCCCTGTCCCAGGGGATTCTTGCCGAGG
TGCCGGTGATCGAGACGGTGGCGCAGCCGCCTGCGGAGGTCCCCCCGCCGTCCGCCGCGCCTGTGGCGGACGCCGACGGA
AACTACCGTTTCCGGATCGAAATGCCCGAGGTGCCGCAGCGCGACGTCGACGCGCTCGCCGTCGAACTCGGCCTGCTCGG
CACCGTCACGCAGGAGACGCTGGCCGACAAGCGGGTCGCCTTTACCCTCGTCACGAGCGAAGGCGTCGACAGCATCGTCG
CGATCTGTTCCTTCGTGCTCGACCCGGACGATCTCAAGATCACCCATGGCAGCAGCGAGCCCGCGCCGGCTGCGCCTGCT
GCTGCGGCGACGGCCGACGCCGATCCGGGCTACGGAATTTTCGAAGAGGCCAAGACCGAGGCGCCCGCGGTGGCGCCGGG
GTCTGCCGCTGCGTCGTCTGCCAGTGTGGAGGCTGGTGAGGCCAGAACTCCCGCTCGGCGCGCGACCGACAAGGAGGGCG
TCAGCGCCGAATCTTCATCGATCCGCGTTGGCGTCGAAAAAGTCGACCAGCTGATCAACCTGGTCGGCGAACTCGTCATC
ACCCAGGCCATGATCGAGCAGCGCATCAACGCGCTCGATCCCATCGTCCACGAGCGACTGCTCAACAGCGCGAGCCAGCT
CGCCCGTAACACCCGGGACCTGCAGGAAGCGGTGATGTCGATCCGCATGATGCCGATGGACTATGTGTTCTCGCGCTTCC
CGCGCATGGTGCGCGACCTGGCGGCCAAGCTCGGCAAGAAGGTCGAGTTCGCCACGCGCGGCGCCGCGACCGAACTCGAC
AAGGGCCTGATCGAGCGCATCGTCGACCCGCTGACCCATCTCGTCCGCAATAGCGTCGACCACGGCATCGAGATGCCCGA
AAAACGGCGCGCGAGCGGCAAGAACGAAAGCGGCAAGCTGACCCTGTCGGCGGCCCATCAAGGCGGCAACATCGTCATCG
AGGTGACCGACGACGGCGGCGGCCTCAATCGCGAAAAGATACTCGCCAAGGCCCGGCAGCAAGGTATTCCGGTGTCCGAC
GCGATGCCCGACAGCGAAGTCTGGCAGCTCATTTTTGCCCCCGGATTTTCCACGGCCGAATTCGTGACCGACGTCTCGGG
ACGCGGCGTCGGCATGGACGTCGTCAAGCGCAATATCACGGCGATGGGCGGCAACGTCGAAATCCAGTCGGTGCCCGGTA
CCGGCACGACGATCGCGATTTCGTTGCCGCTCACGCTCGCGATCCTCGATGGCATGTCGGTGAAGGTCGGCGACGAGGTC
TATATCCTGCCGCTCGGCTACGTCATCGAGTCCCTTCAGCCGGCGGCCGCCGACGTGAAGGAAATCGCCGGCCAGGGCAA
GGTCGTCAAGGTGCGCGAAGAGTATCTGCCGCTGATTCCGCTCTACCAGATCTTCGCGATCGAGCCGAGCTTCGACGACG
CCGCGCGCGGCATCATCGTCATTCTCGAATCCGAAGGCAAGAAAGCGGCGCTGCTCGTCGACAGCTTGGTCGGCCAGCAG
CAGGTCGTGGTCAAGAACCTCGAATCGAACTTCCGCAGGGTGGCGGGCATTTCCGGCGCCACCATCCTTGGCGACGGCGG
TGTTTCGCTGATCCTCGACGTCTCTGCGCTGCTGCGTTCCAGCCACCAGCTCAACGCGGATCCCATTTATTCCTGA

Upstream 100 bases:

>100_bases
AAGCCCTTCGATCCGGCGCGCCTGACCGAAGTGGTGAAGAAACTGATCGGCTGACGCGACGAACGCGCAGCCCTCGAGAG
AACGAAAGACGGAGTCCCAG

Downstream 100 bases:

>100_bases
TACTCCAGAAGGATGCAATCCATGACTCTCCCGATGCAAACCCCGTCCAGCGCGCCGACCGAAGCGGAAGGTGACGGCAA
CGAATATCTCGCCTTCACGC

Product: signal transduction histidine kinase CheA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MTIDMSQFYQVFFDEADELLAEMEKLLLALDVAAPDSEDLNAIFRAAHSIKGGAATFGFTDITEVTHMLESLLDRIRKGE
MALTGEHVDAFLVAKDILAMQMEGHHHGAGVDQSSVDSVCQRLKALSQGILAEVPVIETVAQPPAEVPPPSAAPVADADG
NYRFRIEMPEVPQRDVDALAVELGLLGTVTQETLADKRVAFTLVTSEGVDSIVAICSFVLDPDDLKITHGSSEPAPAAPA
AAATADADPGYGIFEEAKTEAPAVAPGSAAASSASVEAGEARTPARRATDKEGVSAESSSIRVGVEKVDQLINLVGELVI
TQAMIEQRINALDPIVHERLLNSASQLARNTRDLQEAVMSIRMMPMDYVFSRFPRMVRDLAAKLGKKVEFATRGAATELD
KGLIERIVDPLTHLVRNSVDHGIEMPEKRRASGKNESGKLTLSAAHQGGNIVIEVTDDGGGLNREKILAKARQQGIPVSD
AMPDSEVWQLIFAPGFSTAEFVTDVSGRGVGMDVVKRNITAMGGNVEIQSVPGTGTTIAISLPLTLAILDGMSVKVGDEV
YILPLGYVIESLQPAAADVKEIAGQGKVVKVREEYLPLIPLYQIFAIEPSFDDAARGIIVILESEGKKAALLVDSLVGQQ
QVVVKNLESNFRRVAGISGATILGDGGVSLILDVSALLRSSHQLNADPIYS

Sequences:

>Translated_691_residues
MTIDMSQFYQVFFDEADELLAEMEKLLLALDVAAPDSEDLNAIFRAAHSIKGGAATFGFTDITEVTHMLESLLDRIRKGE
MALTGEHVDAFLVAKDILAMQMEGHHHGAGVDQSSVDSVCQRLKALSQGILAEVPVIETVAQPPAEVPPPSAAPVADADG
NYRFRIEMPEVPQRDVDALAVELGLLGTVTQETLADKRVAFTLVTSEGVDSIVAICSFVLDPDDLKITHGSSEPAPAAPA
AAATADADPGYGIFEEAKTEAPAVAPGSAAASSASVEAGEARTPARRATDKEGVSAESSSIRVGVEKVDQLINLVGELVI
TQAMIEQRINALDPIVHERLLNSASQLARNTRDLQEAVMSIRMMPMDYVFSRFPRMVRDLAAKLGKKVEFATRGAATELD
KGLIERIVDPLTHLVRNSVDHGIEMPEKRRASGKNESGKLTLSAAHQGGNIVIEVTDDGGGLNREKILAKARQQGIPVSD
AMPDSEVWQLIFAPGFSTAEFVTDVSGRGVGMDVVKRNITAMGGNVEIQSVPGTGTTIAISLPLTLAILDGMSVKVGDEV
YILPLGYVIESLQPAAADVKEIAGQGKVVKVREEYLPLIPLYQIFAIEPSFDDAARGIIVILESEGKKAALLVDSLVGQQ
QVVVKNLESNFRRVAGISGATILGDGGVSLILDVSALLRSSHQLNADPIYS
>Mature_690_residues
TIDMSQFYQVFFDEADELLAEMEKLLLALDVAAPDSEDLNAIFRAAHSIKGGAATFGFTDITEVTHMLESLLDRIRKGEM
ALTGEHVDAFLVAKDILAMQMEGHHHGAGVDQSSVDSVCQRLKALSQGILAEVPVIETVAQPPAEVPPPSAAPVADADGN
YRFRIEMPEVPQRDVDALAVELGLLGTVTQETLADKRVAFTLVTSEGVDSIVAICSFVLDPDDLKITHGSSEPAPAAPAA
AATADADPGYGIFEEAKTEAPAVAPGSAAASSASVEAGEARTPARRATDKEGVSAESSSIRVGVEKVDQLINLVGELVIT
QAMIEQRINALDPIVHERLLNSASQLARNTRDLQEAVMSIRMMPMDYVFSRFPRMVRDLAAKLGKKVEFATRGAATELDK
GLIERIVDPLTHLVRNSVDHGIEMPEKRRASGKNESGKLTLSAAHQGGNIVIEVTDDGGGLNREKILAKARQQGIPVSDA
MPDSEVWQLIFAPGFSTAEFVTDVSGRGVGMDVVKRNITAMGGNVEIQSVPGTGTTIAISLPLTLAILDGMSVKVGDEVY
ILPLGYVIESLQPAAADVKEIAGQGKVVKVREEYLPLIPLYQIFAIEPSFDDAARGIIVILESEGKKAALLVDSLVGQQQ
VVVKNLESNFRRVAGISGATILGDGGVSLILDVSALLRSSHQLNADPIYS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=677, Percent_Identity=55.096011816839, Blast_Score=685, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73529; Mature: 73397

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDMSQFYQVFFDEADELLAEMEKLLLALDVAAPDSEDLNAIFRAAHSIKGGAATFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCH
DITEVTHMLESLLDRIRKGEMALTGEHVDAFLVAKDILAMQMEGHHHGAGVDQSSVDSVC
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QRLKALSQGILAEVPVIETVAQPPAEVPPPSAAPVADADGNYRFRIEMPEVPQRDVDALA
HHHHHHHHCHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHH
VELGLLGTVTQETLADKRVAFTLVTSEGVDSIVAICSFVLDPDDLKITHGSSEPAPAAPA
HHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
AAATADADPGYGIFEEAKTEAPAVAPGSAAASSASVEAGEARTPARRATDKEGVSAESSS
HHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
IRVGVEKVDQLINLVGELVITQAMIEQRINALDPIVHERLLNSASQLARNTRDLQEAVMS
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRMMPMDYVFSRFPRMVRDLAAKLGKKVEFATRGAATELDKGLIERIVDPLTHLVRNSVD
HHCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HGIEMPEKRRASGKNESGKLTLSAAHQGGNIVIEVTDDGGGLNREKILAKARQQGIPVSD
CCCCCCHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCC
AMPDSEVWQLIFAPGFSTAEFVTDVSGRGVGMDVVKRNITAMGGNVEIQSVPGTGTTIAI
CCCCHHHHEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEE
SLPLTLAILDGMSVKVGDEVYILPLGYVIESLQPAAADVKEIAGQGKVVKVREEYLPLIP
ECCEEEEHHCCCEEEECCEEEEEEHHHHHHHCCCHHHHHHHHHCCCCEEEEHHHHCCCCC
LYQIFAIEPSFDDAARGIIVILESEGKKAALLVDSLVGQQQVVVKNLESNFRRVAGISGA
CEEHEEECCCCCCCCCCEEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
TILGDGGVSLILDVSALLRSSHQLNADPIYS
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TIDMSQFYQVFFDEADELLAEMEKLLLALDVAAPDSEDLNAIFRAAHSIKGGAATFGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCH
DITEVTHMLESLLDRIRKGEMALTGEHVDAFLVAKDILAMQMEGHHHGAGVDQSSVDSVC
HHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QRLKALSQGILAEVPVIETVAQPPAEVPPPSAAPVADADGNYRFRIEMPEVPQRDVDALA
HHHHHHHHCHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHH
VELGLLGTVTQETLADKRVAFTLVTSEGVDSIVAICSFVLDPDDLKITHGSSEPAPAAPA
HHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
AAATADADPGYGIFEEAKTEAPAVAPGSAAASSASVEAGEARTPARRATDKEGVSAESSS
HHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
IRVGVEKVDQLINLVGELVITQAMIEQRINALDPIVHERLLNSASQLARNTRDLQEAVMS
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRMMPMDYVFSRFPRMVRDLAAKLGKKVEFATRGAATELDKGLIERIVDPLTHLVRNSVD
HHCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HGIEMPEKRRASGKNESGKLTLSAAHQGGNIVIEVTDDGGGLNREKILAKARQQGIPVSD
CCCCCCHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCC
AMPDSEVWQLIFAPGFSTAEFVTDVSGRGVGMDVVKRNITAMGGNVEIQSVPGTGTTIAI
CCCCHHHHEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEE
SLPLTLAILDGMSVKVGDEVYILPLGYVIESLQPAAADVKEIAGQGKVVKVREEYLPLIP
ECCEEEEHHCCCEEEECCEEEEEEHHHHHHHCCCHHHHHHHHHCCCCEEEEHHHHCCCCC
LYQIFAIEPSFDDAARGIIVILESEGKKAALLVDSLVGQQQVVVKNLESNFRRVAGISGA
CEEHEEECCCCCCCCCCEEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
TILGDGGVSLILDVSALLRSSHQLNADPIYS
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]