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The map label for this gene is cheW [H]

Identifier: 74317641

GI number: 74317641

Start: 1709276

End: 1709779

Strand: Reverse

Name: cheW [H]

Synonym: Tbd_1623

Alternate gene names: 74317641

Gene position: 1709779-1709276 (Counterclockwise)

Preceding gene: 74317642

Following gene: 74317640

Centisome position: 58.76

GC content: 61.11

Gene sequence:

>504_bases
ATGACTCTCCCGATGCAAACCCCGTCCAGCGCGCCGACCGAAGCGGAAGGTGACGGCAACGAATATCTCGCCTTCACGCT
CGGGCGTGAGGAATACGGCATCGACATCCTGCGTGTGCAGGAGATCCGCGGCTACGAGCCGGTTACGCGCATCGCCAATG
CGCCGGCCTTCATCAAGGGGGTCGTCAACCTGCGCGGAACGATCGTCCCGGTCGTCGACATGCGGATCAAGTTCAACCTC
GGCGAGCCCACCTACGACCAGTTCACGGTCGTGATCATCCTGAACATCGGTGGCCGCGTCGTCGGCATGGTGGTCGACAG
CGTTTCGGACGTCATGACGCTGGCGCCCGAGCAGGTCAAGCCTGCTCCGGAAATCGGGACGACTTTCGATACCGACTATC
TGATCGGTCTCGGCACGCTCGACGACCGCATGCTGATCCTGGTCGATATCGACAAGCTCATGTCGAGCTCCGAAATGGGC
CTGATCGACAAATTGGCAGCCTGA

Upstream 100 bases:

>100_bases
CGGTGTTTCGCTGATCCTCGACGTCTCTGCGCTGCTGCGTTCCAGCCACCAGCTCAACGCGGATCCCATTTATTCCTGAT
ACTCCAGAAGGATGCAATCC

Downstream 100 bases:

>100_bases
AGCTGGAAATATGAAGCACGCAAATAAAAATAAGTAGAGCCCAAAAGCCTCGGTCCGGGAGTCGTTTTTCAGAAAGGCTA
TGGAAATGTTAGCGAACCTG

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTLPMQTPSSAPTEAEGDGNEYLAFTLGREEYGIDILRVQEIRGYEPVTRIANAPAFIKGVVNLRGTIVPVVDMRIKFNL
GEPTYDQFTVVIILNIGGRVVGMVVDSVSDVMTLAPEQVKPAPEIGTTFDTDYLIGLGTLDDRMLILVDIDKLMSSSEMG
LIDKLAA

Sequences:

>Translated_167_residues
MTLPMQTPSSAPTEAEGDGNEYLAFTLGREEYGIDILRVQEIRGYEPVTRIANAPAFIKGVVNLRGTIVPVVDMRIKFNL
GEPTYDQFTVVIILNIGGRVVGMVVDSVSDVMTLAPEQVKPAPEIGTTFDTDYLIGLGTLDDRMLILVDIDKLMSSSEMG
LIDKLAA
>Mature_166_residues
TLPMQTPSSAPTEAEGDGNEYLAFTLGREEYGIDILRVQEIRGYEPVTRIANAPAFIKGVVNLRGTIVPVVDMRIKFNLG
EPTYDQFTVVIILNIGGRVVGMVVDSVSDVMTLAPEQVKPAPEIGTTFDTDYLIGLGTLDDRMLILVDIDKLMSSSEMGL
IDKLAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=153, Percent_Identity=64.7058823529412, Blast_Score=203, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18164; Mature: 18033

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPMQTPSSAPTEAEGDGNEYLAFTLGREEYGIDILRVQEIRGYEPVTRIANAPAFIKG
CCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEEECCCCCHHHHHCCCCHHHHH
VVNLRGTIVPVVDMRIKFNLGEPTYDQFTVVIILNIGGRVVGMVVDSVSDVMTLAPEQVK
HHHCCCEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHCCHHHCC
PAPEIGTTFDTDYLIGLGTLDDRMLILVDIDKLMSSSEMGLIDKLAA
CCCCCCCEECCCEEEEECCCCCCEEEEEEEHHHHCCCCCCCHHHHCC
>Mature Secondary Structure 
TLPMQTPSSAPTEAEGDGNEYLAFTLGREEYGIDILRVQEIRGYEPVTRIANAPAFIKG
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEEECCCCCHHHHHCCCCHHHHH
VVNLRGTIVPVVDMRIKFNLGEPTYDQFTVVIILNIGGRVVGMVVDSVSDVMTLAPEQVK
HHHCCCEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHCCHHHCC
PAPEIGTTFDTDYLIGLGTLDDRMLILVDIDKLMSSSEMGLIDKLAA
CCCCCCCEECCCEEEEECCCCCCEEEEEEEHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]