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The map label for this gene is ycgR

Identifier: 74317615

GI number: 74317615

Start: 1682658

End: 1683425

Strand: Direct

Name: ycgR

Synonym: Tbd_1597

Alternate gene names: 74317615

Gene position: 1682658-1683425 (Clockwise)

Preceding gene: 74317614

Following gene: 74317616

Centisome position: 57.83

GC content: 63.93

Gene sequence:

>768_bases
ATGTCTTCTTCCCCCCCGCAACACGATCTCGGCCACTGCGACGGCGACGACTTCCTCGCGCGTTATACCCTGCATTCACG
CGCCGAAATCCTTTTTCAACTGCGTGCGCTCCAGAAGCGCAAGGTTCTCGTGAATCTCGACCTGAGCGAGAGCCGGCAGA
TCATCGTCACCTCGGTGCTCGCCGTGAACGAAGCCGACAATACGGTGGTTCTCGACAGCGCCCGCGGCGACGCGCTGAAC
AACGAACTGATGTCCGGCAAGGGGGCCGAGTTCGTCGCCCAGCTCGACGGCGTCTCGATCTCCTTCAGCATCGGCGCGGT
GAGCCTGTGCGAGTACGAAAAGCTCCCCGCGCTGCGAATTCCCGTGCCGACCTCGCTGATCCGTCTACAGCGACGCGAAC
ACTTCCGGGTTCCGCTGCCAATCGCCAACCCGGTCAAGTGCATCGTTCCCTCGCCCTGGGAAGAAAGCAAAGAACAGATC
ACGACGCACCTCGTCGACATCGGCTGCGGCGGCGTCGCGCTGACCGACATCGGCGCCCGCCTCGGCACCGAAAGCGGTCG
GCTGCTCCGCGGGTGCCGGCTGCTGCTCCCCGAAACCGACGTGGTCGTCACCACCCTGGAGATCCGCAACTCGGCGCAAA
TCCGCCTGCAGAACGGCAGCTTCCAGACCCGCCTGGGCTGCAAATTCGTCGACCTGCCCAACGATATGGCCGCGCACCTG
CAGCGCTTCGTCATGAATATCGAGCGCGCACGGCGCAACCGCCTGTAA

Upstream 100 bases:

>100_bases
CGCCGCAACTGTACATCGCCGTCGCGGAATTGCTGGCGTGGCTCTATCATCTGGAAGAAACCGGCGACCGACGCCTATCG
CATCCTCCCACTTGAGCACA

Downstream 100 bases:

>100_bases
TTCCGCGCCACCCGTAAAAACACTCAAGGAGCCGGTCATGCAAACGATCCAGCAAGAGATAGACGAGAGAACCAACCTCA
CGAGTTCCAATAAACTCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSSSPPQHDLGHCDGDDFLARYTLHSRAEILFQLRALQKRKVLVNLDLSESRQIIVTSVLAVNEADNTVVLDSARGDALN
NELMSGKGAEFVAQLDGVSISFSIGAVSLCEYEKLPALRIPVPTSLIRLQRREHFRVPLPIANPVKCIVPSPWEESKEQI
TTHLVDIGCGGVALTDIGARLGTESGRLLRGCRLLLPETDVVVTTLEIRNSAQIRLQNGSFQTRLGCKFVDLPNDMAAHL
QRFVMNIERARRNRL

Sequences:

>Translated_255_residues
MSSSPPQHDLGHCDGDDFLARYTLHSRAEILFQLRALQKRKVLVNLDLSESRQIIVTSVLAVNEADNTVVLDSARGDALN
NELMSGKGAEFVAQLDGVSISFSIGAVSLCEYEKLPALRIPVPTSLIRLQRREHFRVPLPIANPVKCIVPSPWEESKEQI
TTHLVDIGCGGVALTDIGARLGTESGRLLRGCRLLLPETDVVVTTLEIRNSAQIRLQNGSFQTRLGCKFVDLPNDMAAHL
QRFVMNIERARRNRL
>Mature_254_residues
SSSPPQHDLGHCDGDDFLARYTLHSRAEILFQLRALQKRKVLVNLDLSESRQIIVTSVLAVNEADNTVVLDSARGDALNN
ELMSGKGAEFVAQLDGVSISFSIGAVSLCEYEKLPALRIPVPTSLIRLQRREHFRVPLPIANPVKCIVPSPWEESKEQIT
THLVDIGCGGVALTDIGARLGTESGRLLRGCRLLLPETDVVVTTLEIRNSAQIRLQNGSFQTRLGCKFVDLPNDMAAHLQ
RFVMNIERARRNRL

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCGR_THIDA (Q3SIH8)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315355.1
- ProteinModelPortal:   Q3SIH8
- SMR:   Q3SIH8
- STRING:   Q3SIH8
- GeneID:   3672982
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1597
- NMPDR:   fig|292415.3.peg.1596
- eggNOG:   COG5581
- OMA:   QLGFRFL
- BioCyc:   TDEN292415:TBD_1597-MONOMER
- HAMAP:   MF_01457
- InterPro:   IPR009875
- InterPro:   IPR009926

Pfam domain/function: PF07238 PilZ; PF07317 YcgR

EC number: NA

Molecular weight: Translated: 28229; Mature: 28098

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPPQHDLGHCDGDDFLARYTLHSRAEILFQLRALQKRKVLVNLDLSESRQIIVTSVL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEEEE
AVNEADNTVVLDSARGDALNNELMSGKGAEFVAQLDGVSISFSIGAVSLCEYEKLPALRI
EECCCCCEEEEECCCCCCHHHHHHCCCCCCEEEEECCCEEEEECCEEEEEHHHCCCEEEC
PVPTSLIRLQRREHFRVPLPIANPVKCIVPSPWEESKEQITTHLVDIGCGGVALTDIGAR
CCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHH
LGTESGRLLRGCRLLLPETDVVVTTLEIRNSAQIRLQNGSFQTRLGCKFVDLPNDMAAHL
HCCCCCHHHHCEEEECCCCCEEEEEEEECCCEEEEEECCCEEEECCEEEEECCCHHHHHH
QRFVMNIERARRNRL
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSSPPQHDLGHCDGDDFLARYTLHSRAEILFQLRALQKRKVLVNLDLSESRQIIVTSVL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEEEE
AVNEADNTVVLDSARGDALNNELMSGKGAEFVAQLDGVSISFSIGAVSLCEYEKLPALRI
EECCCCCEEEEECCCCCCHHHHHHCCCCCCEEEEECCCEEEEECCEEEEEHHHCCCEEEC
PVPTSLIRLQRREHFRVPLPIANPVKCIVPSPWEESKEQITTHLVDIGCGGVALTDIGAR
CCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHH
LGTESGRLLRGCRLLLPETDVVVTTLEIRNSAQIRLQNGSFQTRLGCKFVDLPNDMAAHL
HCCCCCHHHHCEEEECCCCCEEEEEEEECCCEEEEEECCCEEEECCEEEEECCCHHHHHH
QRFVMNIERARRNRL
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA