Click here to switch to the map view.

The map label for this gene is aatA [H]

Identifier: 74317587

GI number: 74317587

Start: 1652969

End: 1654165

Strand: Direct

Name: aatA [H]

Synonym: Tbd_1569

Alternate gene names: 74317587

Gene position: 1652969-1654165 (Clockwise)

Preceding gene: 74317585

Following gene: 74317588

Centisome position: 56.81

GC content: 66.83

Gene sequence:

>1197_bases
GTGGAACTCTCCCGCCGCGTACAGGCCATCAAGCCCTCCCCGACGCTCGCCGTCACCGCCCGCGCCGCCGCCCTCAAGGC
CACCGGTCGCGACATCATCGGCCTCGGCGCCGGCGAGCCCGACTTCGATACGCCGCAACACATCAAGGACGCGGCGATCA
AGGCGATCGACGGCGGCTTCACCAAGTACACGGCGGTCGACGGCACGCCGAGCCTGAAGGCGGCGATCATCGCCAAGTTC
AAGCGCGACAACGGCCTCGACTACACGCCGAAGCAGATCCTCGTCTCATGCGGCGGCAAGCAGAGCTTCTTCAACCTCGT
CCAGGCCGTGATCGACCCCGACGACGAGGTCATCATTCCGGCGCCCTACTGGGTGTCCTACCCCGACATCGTGATCCTCG
CCGATGGCAAACCTGTCATCGTCGAGGCCGGCATCGAGCAGGGCTTCAAAATCACACCCGCGCAGCTCGAGGCGGCGATC
ACGCCGAAAACGCGCCTCTTCGTCATCAACAGCCCGTCGAACCCGACCGGCGCGGTCTACTCGAAGGACGAACTCGCCGC
GCTCGGCGACGTGTTGCGCCGCCATCCGCGCGTGCTCATCGCCTCGGACGACATGTATGAGCATATCCGCCTCGACGGCG
CGCCCTTCGTCAACATCCTCAACGCCTGCCCCGACCTCTACGACCGCACGCTCGTGCTGAACGGCGTGTCGAAGGCCTAC
TCAATGACCGGCTGGCGGATCGGCTACGCCGCCGGCCCCGAAGCGATCCTGCGCGCGATGACCAACGTGCAGTCGCAATC
GACCTCGAACCCGACCTCGATCTCACAGGTCGCCGCCGAAGCGGCGCTCAACGGCGACCAGGGCTGCATCACGCCGATGC
TCGACGCGTTCAAGGCACGTCACCGCTTCGTCGTCGACGCGCTCAACGCGATTCCCGGCTTCAAGTGCGTCGATAGCGGC
GGCGCGTTCTACGCCTTCCCCGACGTGCGGCCGGCGATCCAGGCGCTGCTCGCGCGCGACGTGATCGAGCAAGGCACCGA
CATCGCCTTCTCCGAATACCTGCTTGAGTCGGCCGACGTCGCAGTGGTTCCCGGCTCGGCCTTCGGCGCCGAGGGCTACA
TCCGCCTGTCGTTCGCGACCTCGCAGGCCAACCTCGACAAGGCGCTCAAGCGGATCGCCCAGGCGATCGCCGGCTGA

Upstream 100 bases:

>100_bases
CGACGCGATCCTCACTTGAAACATTCGGGTTAAAATCGCGCGGCAAAAAACTCACTGATAGTAGCACCCGTTTCGTCGCG
GGCGCCCCCAAGGAACCATT

Downstream 100 bases:

>100_bases
GCGCTGGCCCGGCGCGCGCGCTGAAGGTAGGCTAGCGCCATGCGCCTGCCCGCCCTGCCCCCCGTCCGCGGCCCGCTCTC
GCGGATCGTCCAGCTCGGCT

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MELSRRVQAIKPSPTLAVTARAAALKATGRDIIGLGAGEPDFDTPQHIKDAAIKAIDGGFTKYTAVDGTPSLKAAIIAKF
KRDNGLDYTPKQILVSCGGKQSFFNLVQAVIDPDDEVIIPAPYWVSYPDIVILADGKPVIVEAGIEQGFKITPAQLEAAI
TPKTRLFVINSPSNPTGAVYSKDELAALGDVLRRHPRVLIASDDMYEHIRLDGAPFVNILNACPDLYDRTLVLNGVSKAY
SMTGWRIGYAAGPEAILRAMTNVQSQSTSNPTSISQVAAEAALNGDQGCITPMLDAFKARHRFVVDALNAIPGFKCVDSG
GAFYAFPDVRPAIQALLARDVIEQGTDIAFSEYLLESADVAVVPGSAFGAEGYIRLSFATSQANLDKALKRIAQAIAG

Sequences:

>Translated_398_residues
MELSRRVQAIKPSPTLAVTARAAALKATGRDIIGLGAGEPDFDTPQHIKDAAIKAIDGGFTKYTAVDGTPSLKAAIIAKF
KRDNGLDYTPKQILVSCGGKQSFFNLVQAVIDPDDEVIIPAPYWVSYPDIVILADGKPVIVEAGIEQGFKITPAQLEAAI
TPKTRLFVINSPSNPTGAVYSKDELAALGDVLRRHPRVLIASDDMYEHIRLDGAPFVNILNACPDLYDRTLVLNGVSKAY
SMTGWRIGYAAGPEAILRAMTNVQSQSTSNPTSISQVAAEAALNGDQGCITPMLDAFKARHRFVVDALNAIPGFKCVDSG
GAFYAFPDVRPAIQALLARDVIEQGTDIAFSEYLLESADVAVVPGSAFGAEGYIRLSFATSQANLDKALKRIAQAIAG
>Mature_398_residues
MELSRRVQAIKPSPTLAVTARAAALKATGRDIIGLGAGEPDFDTPQHIKDAAIKAIDGGFTKYTAVDGTPSLKAAIIAKF
KRDNGLDYTPKQILVSCGGKQSFFNLVQAVIDPDDEVIIPAPYWVSYPDIVILADGKPVIVEAGIEQGFKITPAQLEAAI
TPKTRLFVINSPSNPTGAVYSKDELAALGDVLRRHPRVLIASDDMYEHIRLDGAPFVNILNACPDLYDRTLVLNGVSKAY
SMTGWRIGYAAGPEAILRAMTNVQSQSTSNPTSISQVAAEAALNGDQGCITPMLDAFKARHRFVVDALNAIPGFKCVDSG
GAFYAFPDVRPAIQALLARDVIEQGTDIAFSEYLLESADVAVVPGSAFGAEGYIRLSFATSQANLDKALKRIAQAIAG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=419, Percent_Identity=25.5369928400955, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI169881279, Length=419, Percent_Identity=25.5369928400955, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI56713256, Length=416, Percent_Identity=25.2403846153846, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI56713254, Length=416, Percent_Identity=25.2403846153846, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI169881281, Length=363, Percent_Identity=23.1404958677686, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4507369, Length=401, Percent_Identity=23.1920199501247, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=27.3209549071618, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=28.2178217821782, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=28.2722513089005, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=408, Percent_Identity=25.4901960784314, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=408, Percent_Identity=25.4901960784314, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=387, Percent_Identity=24.5478036175711, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=21.5789473684211, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71981209, Length=352, Percent_Identity=23.0113636363636, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=24.8081841432225, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=360, Percent_Identity=23.8888888888889, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573069, Length=420, Percent_Identity=25.2380952380952, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24646114, Length=420, Percent_Identity=25.2380952380952, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573067, Length=420, Percent_Identity=25.2380952380952, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573065, Length=420, Percent_Identity=25.2380952380952, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=22.5464190981432, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641770, Length=363, Percent_Identity=23.6914600550964, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641760, Length=363, Percent_Identity=23.6914600550964, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641768, Length=363, Percent_Identity=23.6914600550964, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641766, Length=363, Percent_Identity=23.6914600550964, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641764, Length=363, Percent_Identity=23.6914600550964, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551451, Length=363, Percent_Identity=23.6914600550964, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42394; Mature: 42394

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSRRVQAIKPSPTLAVTARAAALKATGRDIIGLGAGEPDFDTPQHIKDAAIKAIDGGF
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TKYTAVDGTPSLKAAIIAKFKRDNGLDYTPKQILVSCGGKQSFFNLVQAVIDPDDEVIIP
EEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHEECCCHHHHHHHHHHHHCCCCCEEEC
APYWVSYPDIVILADGKPVIVEAGIEQGFKITPAQLEAAITPKTRLFVINSPSNPTGAVY
CCCEECCCCEEEEECCCEEEEECCCCCCCEECHHHHHEEECCCEEEEEEECCCCCCCCEE
SKDELAALGDVLRRHPRVLIASDDMYEHIRLDGAPFVNILNACPDLYDRTLVLNGVSKAY
CHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCCCHHHHHHHHCHHHHCCEEEEECHHHHH
SMTGWRIGYAAGPEAILRAMTNVQSQSTSNPTSISQVAAEAALNGDQGCITPMLDAFKAR
HCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
HRFVVDALNAIPGFKCVDSGGAFYAFPDVRPAIQALLARDVIEQGTDIAFSEYLLESADV
HHHHHHHHHHCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCE
AVVPGSAFGAEGYIRLSFATSQANLDKALKRIAQAIAG
EEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELSRRVQAIKPSPTLAVTARAAALKATGRDIIGLGAGEPDFDTPQHIKDAAIKAIDGGF
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TKYTAVDGTPSLKAAIIAKFKRDNGLDYTPKQILVSCGGKQSFFNLVQAVIDPDDEVIIP
EEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHEECCCHHHHHHHHHHHHCCCCCEEEC
APYWVSYPDIVILADGKPVIVEAGIEQGFKITPAQLEAAITPKTRLFVINSPSNPTGAVY
CCCEECCCCEEEEECCCEEEEECCCCCCCEECHHHHHEEECCCEEEEEEECCCCCCCCEE
SKDELAALGDVLRRHPRVLIASDDMYEHIRLDGAPFVNILNACPDLYDRTLVLNGVSKAY
CHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCCCHHHHHHHHCHHHHCCEEEEECHHHHH
SMTGWRIGYAAGPEAILRAMTNVQSQSTSNPTSISQVAAEAALNGDQGCITPMLDAFKAR
HCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
HRFVVDALNAIPGFKCVDSGGAFYAFPDVRPAIQALLARDVIEQGTDIAFSEYLLESADV
HHHHHHHHHHCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCE
AVVPGSAFGAEGYIRLSFATSQANLDKALKRIAQAIAG
EEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA