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The map label for this gene is arnT [H]

Identifier: 74317552

GI number: 74317552

Start: 1618511

End: 1620109

Strand: Reverse

Name: arnT [H]

Synonym: Tbd_1534

Alternate gene names: 74317552

Gene position: 1620109-1618511 (Counterclockwise)

Preceding gene: 74317553

Following gene: 74317546

Centisome position: 55.68

GC content: 70.04

Gene sequence:

>1599_bases
ATGTCACGTAGTTGCGAACCGGGGGGGCGCGGTTATCTGCTGCTGAGCCTGCTGCTACTGGCGGGCCTGACGATGGTCGC
GCTGATGACGCGGCCGCTCACGCCGATCGACGAGACACGCTACGTCAGCGCGGCCTGGGAGATGTGGCTGCGCGGCGATT
TCCTGGTCCCGTTCAAGAACGGCGAGCCCTACAGCCACAAGCCGCCGCTGATGTTCTGGATGATCCACGCGGGGTGGGCC
ATGTTCGGGGTCAACGACTGGTGGCCGCGTCTGGTCATGCCGCTCTTTTCTGCACTGGCCCTGCTGCTGACCTATCGGCT
TGCACGCCGCCTGTGGCCGGGACACGCGGGCCTCGGCGGCGAGGCGACGCTGGTCCTCGTCAGCGCGCTCTGGTGGATCG
TCTTTTCGACGACGCTGATGTTCGACGTGATGCTCGCATGCTGGGCGCTGCTTGGCGCGCACGGCGTGCTGACCGCGGCC
GAGGGCAAGCGTCGCGGTTTCGTGCTGCTGGGGATCGCGATCGGAATGGGCGTACTGAGCAAGGGCCCGGTCATCCTGCT
CGACGTGCTGCCGGTCGCAGTGCTCGCGCCGTGGTGGAACCCCGGTCTCAAATGGCATCGCTGGTTTGGCGGCGTCGGGC
TCGCAGTGCTGCTCGGCGCGCTGCTCGCGCTGGGCTGGGCGATCCCCGCGGGATTCGCCGGCGGCGAAGCCTATCGCAAT
GCGATCTTCTGGGGGCAGACGGCCGACCGCATGGTCGAATCGTTCGCGCATCGGCGCCCGGTGTGGTGGTATTTGCCGCT
ATTGCCCGTCCTGCTCTTTCCGTGGTTCGTCTGGTCCGCGTGGTGGCGGGCGCTCGCGCGGCACCGACGCGCCGGCCTCG
ATCGCGGGCTGCGCTTCTGCCTGGCGTGGATGCTGCCCGTGTTCATCGCGTTTTCCTTCATCAGCGGCAAGCAACCCCAC
TACCTCGTGCCCTTGTTCCCGCCGTTCGCGCTGTTCGCCGTGCGGCTATTGTCCGCGCATCCGGCACGCGGCGTCGCGCT
GCCGGCCCTGCTTGCCGCCCTGCTCGGCGTCGCGCTCGTTGCGGCCGCGAGCGGGCAGATCCCCGCGGTGCGCGACCAGG
TTCTCGCGCCGCCGCCGGTGTGGCCCGGCGTGACGCTTGTCGTCGTGGCTATCGCTGCGTGGTTCGCCGGCCGCCGGGGT
GTGCCCGCGGTGCCGAACCTCGCCGTGCTCGGCGCGACGACGCTGGCCCTGGTTCAGCTGGTGGTGGGACCGGCGCTCGG
CGCGCGCTACGACGTCAAGCCGCTCGCGCAGGCGATCGCCGCGGTGCAGCGGGAGGGGCGTCCGGTCGCGAATCTCGCGA
CCTATCACGCCCAGTATCAGTTTCTCGGGCGGCTCGAGGCGCCGCTGGTCCAGCTGCGCGGCCCCGAAACGGCGCGCTGG
CTCGCGGCGCACCCCGAGGCCTATGCTGTCGTGTATCTGGAGGATGAGAGCGCGCTCGCTTCGATTCCGGCCCGGCACAA
GCAGGCGTATCGCGGCGGCGCGGTGGCGCTGGTCGATGCCCATGCGGCGACGGCGTTGCTCGCCGCCCACGTCGAGTAG

Upstream 100 bases:

>100_bases
GTTTCAAGCGGACTCGGTGTGTATCTCTACCAGCATTTTCGGCGCGGACCCGGCCTCGACCAGGAAATCGACGCGGCGCT
CGAACCCCGGCGGGGGCACG

Downstream 100 bases:

>100_bases
ACCCTCAGGCTTCGGCGTCGCGCTGCGGCAGCACGACTTCGCGCGACGGCGAAATCGTCGAGATGGCGTGCTTGAAAATC
ATCTGTGCGGCCTGGTCCTG

Product: putative glycosyltransferase

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase [H]

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSRSCEPGGRGYLLLSLLLLAGLTMVALMTRPLTPIDETRYVSAAWEMWLRGDFLVPFKNGEPYSHKPPLMFWMIHAGWA
MFGVNDWWPRLVMPLFSALALLLTYRLARRLWPGHAGLGGEATLVLVSALWWIVFSTTLMFDVMLACWALLGAHGVLTAA
EGKRRGFVLLGIAIGMGVLSKGPVILLDVLPVAVLAPWWNPGLKWHRWFGGVGLAVLLGALLALGWAIPAGFAGGEAYRN
AIFWGQTADRMVESFAHRRPVWWYLPLLPVLLFPWFVWSAWWRALARHRRAGLDRGLRFCLAWMLPVFIAFSFISGKQPH
YLVPLFPPFALFAVRLLSAHPARGVALPALLAALLGVALVAAASGQIPAVRDQVLAPPPVWPGVTLVVVAIAAWFAGRRG
VPAVPNLAVLGATTLALVQLVVGPALGARYDVKPLAQAIAAVQREGRPVANLATYHAQYQFLGRLEAPLVQLRGPETARW
LAAHPEAYAVVYLEDESALASIPARHKQAYRGGAVALVDAHAATALLAAHVE

Sequences:

>Translated_532_residues
MSRSCEPGGRGYLLLSLLLLAGLTMVALMTRPLTPIDETRYVSAAWEMWLRGDFLVPFKNGEPYSHKPPLMFWMIHAGWA
MFGVNDWWPRLVMPLFSALALLLTYRLARRLWPGHAGLGGEATLVLVSALWWIVFSTTLMFDVMLACWALLGAHGVLTAA
EGKRRGFVLLGIAIGMGVLSKGPVILLDVLPVAVLAPWWNPGLKWHRWFGGVGLAVLLGALLALGWAIPAGFAGGEAYRN
AIFWGQTADRMVESFAHRRPVWWYLPLLPVLLFPWFVWSAWWRALARHRRAGLDRGLRFCLAWMLPVFIAFSFISGKQPH
YLVPLFPPFALFAVRLLSAHPARGVALPALLAALLGVALVAAASGQIPAVRDQVLAPPPVWPGVTLVVVAIAAWFAGRRG
VPAVPNLAVLGATTLALVQLVVGPALGARYDVKPLAQAIAAVQREGRPVANLATYHAQYQFLGRLEAPLVQLRGPETARW
LAAHPEAYAVVYLEDESALASIPARHKQAYRGGAVALVDAHAATALLAAHVE
>Mature_531_residues
SRSCEPGGRGYLLLSLLLLAGLTMVALMTRPLTPIDETRYVSAAWEMWLRGDFLVPFKNGEPYSHKPPLMFWMIHAGWAM
FGVNDWWPRLVMPLFSALALLLTYRLARRLWPGHAGLGGEATLVLVSALWWIVFSTTLMFDVMLACWALLGAHGVLTAAE
GKRRGFVLLGIAIGMGVLSKGPVILLDVLPVAVLAPWWNPGLKWHRWFGGVGLAVLLGALLALGWAIPAGFAGGEAYRNA
IFWGQTADRMVESFAHRRPVWWYLPLLPVLLFPWFVWSAWWRALARHRRAGLDRGLRFCLAWMLPVFIAFSFISGKQPHY
LVPLFPPFALFAVRLLSAHPARGVALPALLAALLGVALVAAASGQIPAVRDQVLAPPPVWPGVTLVVVAIAAWFAGRRGV
PAVPNLAVLGATTLALVQLVVGPALGARYDVKPLAQAIAAVQREGRPVANLATYHAQYQFLGRLEAPLVQLRGPETARWL
AAHPEAYAVVYLEDESALASIPARHKQAYRGGAVALVDAHAATALLAAHVE

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Escherichia coli, GI1788591, Length=333, Percent_Identity=28.2282282282282, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 57955; Mature: 57824

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSCEPGGRGYLLLSLLLLAGLTMVALMTRPLTPIDETRYVSAAWEMWLRGDFLVPFKN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCC
GEPYSHKPPLMFWMIHAGWAMFGVNDWWPRLVMPLFSALALLLTYRLARRLWPGHAGLGG
CCCCCCCCCCEEEEEHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EATLVLVSALWWIVFSTTLMFDVMLACWALLGAHGVLTAAEGKRRGFVLLGIAIGMGVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEHHHHHHHCC
KGPVILLDVLPVAVLAPWWNPGLKWHRWFGGVGLAVLLGALLALGWAIPAGFAGGEAYRN
CCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
AIFWGQTADRMVESFAHRRPVWWYLPLLPVLLFPWFVWSAWWRALARHRRAGLDRGLRFC
HEEECCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LAWMLPVFIAFSFISGKQPHYLVPLFPPFALFAVRLLSAHPARGVALPALLAALLGVALV
HHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AAASGQIPAVRDQVLAPPPVWPGVTLVVVAIAAWFAGRRGVPAVPNLAVLGATTLALVQL
HHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VVGPALGARYDVKPLAQAIAAVQREGRPVANLATYHAQYQFLGRLEAPLVQLRGPETARW
HHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHH
LAAHPEAYAVVYLEDESALASIPARHKQAYRGGAVALVDAHAATALLAAHVE
HEECCCEEEEEEEECCHHHHHCCHHHHHHHCCCCEEEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
SRSCEPGGRGYLLLSLLLLAGLTMVALMTRPLTPIDETRYVSAAWEMWLRGDFLVPFKN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCC
GEPYSHKPPLMFWMIHAGWAMFGVNDWWPRLVMPLFSALALLLTYRLARRLWPGHAGLGG
CCCCCCCCCCEEEEEHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EATLVLVSALWWIVFSTTLMFDVMLACWALLGAHGVLTAAEGKRRGFVLLGIAIGMGVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEHHHHHHHCC
KGPVILLDVLPVAVLAPWWNPGLKWHRWFGGVGLAVLLGALLALGWAIPAGFAGGEAYRN
CCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
AIFWGQTADRMVESFAHRRPVWWYLPLLPVLLFPWFVWSAWWRALARHRRAGLDRGLRFC
HEEECCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LAWMLPVFIAFSFISGKQPHYLVPLFPPFALFAVRLLSAHPARGVALPALLAALLGVALV
HHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AAASGQIPAVRDQVLAPPPVWPGVTLVVVAIAAWFAGRRGVPAVPNLAVLGATTLALVQL
HHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VVGPALGARYDVKPLAQAIAAVQREGRPVANLATYHAQYQFLGRLEAPLVQLRGPETARW
HHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHH
LAAHPEAYAVVYLEDESALASIPARHKQAYRGGAVALVDAHAATALLAAHVE
HEECCCEEEEEEEECCHHHHHCCHHHHHHHCCCCEEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA