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The map label for this gene is lolA

Identifier: 74317515

GI number: 74317515

Start: 1588265

End: 1588873

Strand: Reverse

Name: lolA

Synonym: Tbd_1497

Alternate gene names: 74317515

Gene position: 1588873-1588265 (Counterclockwise)

Preceding gene: 74317516

Following gene: 74317514

Centisome position: 54.6

GC content: 65.85

Gene sequence:

>609_bases
ATGCGTCCACTTTTCCTGCTGTTTGCGCTTGTCCTGACCCACGCCGCCCACGCCGGCGGCGTCGAGCGTCTGAAGGCGTT
CATCGCCGGCGCCAAAACGGCCGAGGCCGACTTCACCCAGACCGTCGCCGACCGCAACAACCGCGTGACCCAGGAGGCGA
GCGGAAAAATGGCGTTCGCGCGTCCCGGCAAGTTCCGCTGGGATTACCGCGCGCCCTACGAGCAGGTCATCGTCGGCGAC
GGCGCCAAGCTCTGGCTTTATGACGCCGACCTCGACCAGGTCACGGTCAAGCCGCTCGGCGAAGTCATCGCCGGCACGCC
GGCCGCGCTCCTGGCCGGCGACGACGCGATCGAAAAATACTTCAGCCTGAAGAACGCCGGCGAATCGGGCGGCCTCGAAT
GGCTCGAAGCGACGCCAAAAAGCCGTGACACGAGCTTCGAGCGCATCCGCATGGGCTTTAAGGGCGACGTGCTCGTGCAG
ATGGAACTCTTCGACACCTTCGGCCAGCGCACCACGCTCAAGCTTTCGAACTTCGCGCGCAACCCGCGCATCGCGCCGTC
GCGCTTCGTCTTCACGCCGCCGAAGGGGGCCGACGTTATCGGCGAGTGA

Upstream 100 bases:

>100_bases
CGGCAGCAAGACCGCAAAGCAGCAGTAAACTTTCGCAGTCCCGCAAGGTCTGCCTAGTGCGCCCGCGTGGCGCACTTTTT
ATTTCCGGAACCGAAAAGCC

Downstream 100 bases:

>100_bases
CAGGCGGGCGCTGCTGACGTTCACGCCATGCCCGACGCCTGAAATCGCGGCACAATAAGCCTCGCGCCCAACCACCATGT
GCCCCCAGGACCTCTTCTCG

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MRPLFLLFALVLTHAAHAGGVERLKAFIAGAKTAEADFTQTVADRNNRVTQEASGKMAFARPGKFRWDYRAPYEQVIVGD
GAKLWLYDADLDQVTVKPLGEVIAGTPAALLAGDDAIEKYFSLKNAGESGGLEWLEATPKSRDTSFERIRMGFKGDVLVQ
MELFDTFGQRTTLKLSNFARNPRIAPSRFVFTPPKGADVIGE

Sequences:

>Translated_202_residues
MRPLFLLFALVLTHAAHAGGVERLKAFIAGAKTAEADFTQTVADRNNRVTQEASGKMAFARPGKFRWDYRAPYEQVIVGD
GAKLWLYDADLDQVTVKPLGEVIAGTPAALLAGDDAIEKYFSLKNAGESGGLEWLEATPKSRDTSFERIRMGFKGDVLVQ
MELFDTFGQRTTLKLSNFARNPRIAPSRFVFTPPKGADVIGE
>Mature_202_residues
MRPLFLLFALVLTHAAHAGGVERLKAFIAGAKTAEADFTQTVADRNNRVTQEASGKMAFARPGKFRWDYRAPYEQVIVGD
GAKLWLYDADLDQVTVKPLGEVIAGTPAALLAGDDAIEKYFSLKNAGESGGLEWLEATPKSRDTSFERIRMGFKGDVLVQ
MELFDTFGQRTTLKLSNFARNPRIAPSRFVFTPPKGADVIGE

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=196, Percent_Identity=27.0408163265306, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_THIDA (Q3SIS5)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315255.1
- ProteinModelPortal:   Q3SIS5
- SMR:   Q3SIS5
- STRING:   Q3SIS5
- GeneID:   3672910
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1497
- NMPDR:   fig|292415.3.peg.1497
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- PhylomeDB:   Q3SIS5
- BioCyc:   TDEN292415:TBD_1497-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22200; Mature: 22200

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLFLLFALVLTHAAHAGGVERLKAFIAGAKTAEADFTQTVADRNNRVTQEASGKMAFA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCEEEE
RPGKFRWDYRAPYEQVIVGDGAKLWLYDADLDQVTVKPLGEVIAGTPAALLAGDDAIEKY
CCCCEECCCCCCHHEEEECCCCEEEEEECCCCEEEHHHHHHHHCCCCHHEEECCHHHHHH
FSLKNAGESGGLEWLEATPKSRDTSFERIRMGFKGDVLVQMELFDTFGQRTTLKLSNFAR
HHHHCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCCEEEEEHHHHHCCCCEEEEHHHHCC
NPRIAPSRFVFTPPKGADVIGE
CCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MRPLFLLFALVLTHAAHAGGVERLKAFIAGAKTAEADFTQTVADRNNRVTQEASGKMAFA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCEEEE
RPGKFRWDYRAPYEQVIVGDGAKLWLYDADLDQVTVKPLGEVIAGTPAALLAGDDAIEKY
CCCCEECCCCCCHHEEEECCCCEEEEEECCCCEEEHHHHHHHHCCCCHHEEECCHHHHHH
FSLKNAGESGGLEWLEATPKSRDTSFERIRMGFKGDVLVQMELFDTFGQRTTLKLSNFAR
HHHHCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCCEEEEEHHHHHCCCCEEEEHHHHCC
NPRIAPSRFVFTPPKGADVIGE
CCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA