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The map label for this gene is sthA [C]

Identifier: 74317493

GI number: 74317493

Start: 1562054

End: 1563490

Strand: Reverse

Name: sthA [C]

Synonym: Tbd_1475

Alternate gene names: 74317493

Gene position: 1563490-1562054 (Counterclockwise)

Preceding gene: 74317494

Following gene: 74317492

Centisome position: 53.73

GC content: 70.7

Gene sequence:

>1437_bases
ATGCCCGTGTTGCATCGCCCGGAGCAGGCGCTCACCGTGACCCTGCCGCCGCGCAGCGCGCAGGTGGCCGCCGATTGCGA
CGTGCTCGTCGTCGGCGGCGGCCCGGCCGGCATCGGCGCCGCGCTCGGCGCGGCGGCGGCCGGCGCGCGCACCGTGCTGG
TCGAGCGCTACGGATTTCTCGGCGGCAACGCGACCGCGGCGCTCGTGATGCCGCTGATGTCCTTCCACACGAGCCGACCG
CAGATCGAGCAATCCGGCGCGCATACGCTCCTGCCGACCGACCACGGCCCGGGAACGCCGGTCATCGCCGGCGCGGTACG
ACAGTTCATCGCGCGCCTGCTCGCCCACGGCGGCGCGGTGCCGCCGGATCTGAGCACCGGCTACACGGTGCCCTTCGACC
CCGAGCTGTTCAAGCTCACTGCGCTCGAACTGCTCGACGAGGCCGGCGTGTCCTTCCTCTTCCACGCCTTCGCGTCGGGC
GTGCTCGGCGAGGGACGCTGCGGCGGGGTCGTGTTCGAAACCAAGGGCGGCCCGCAGGTCGTGCGCGCGCGCATGATCGT
CGACGCAACCGGGGACGGCGACATCGCGGTGGCGGCCGGCGCGCCTTACGAGATCGGGCGCGAGGCCGACGGCATGGTGC
AGCCGATGACGCTGATGTTTCGCGTCGCCGATTTCGAGCGCGTCGGCTTCGAGACCTATGTCGCCGCGCACCCCGATCAA
TGGCGCGGCGTGCACGGCTTGTGGGATCTCGTCGCACGTGCGACCGCGGCGGGCGACCTCGACCTGCCGCGTGAAGACAT
CCTGCTGTTCGCGACCCCGCATCTGCATGAAGTCAGCGTCAACAGCACGCGCGTCACGGCCCATGACCGAAGGCTGCTCG
GCAGCGACCCCTTCGACCTCAGCTACGCGGAATGGGTGAGCCGCGGGCAGATGCGACAGGTCGCCGCATTCCTGCGCAAG
TACGTGCCGGGGTTCGAGGAGTCGTACGCGGTGCAAAGCGGCGTCCAGATCGGCGTGCGCGAGACGCGGCGAATACGCGG
CGACTATCGCCTGAGCGCCGACGACGTGCTCACGGCACGCAAGTTCGGCGACGTCATCGCGCGCAGCACCTATCCGATCG
ACATTCACAACGCGACCGGCACGGGCACGGTGTTGAAGCGCCTGCCGCCGAACGAGGCCTACGACATTCCGCTGCGCTGC
CTGCTGCCGCAGGGGCTCGACAACGTGCTGACCGCCGGGCGCTGCATTTCGGGCGACAGCGAGGCGCACTCGTCCTACCG
CGTGATGGTCGTCTGCATGGCGACCGGGCAGGCGGCCGGCGCCTGCGCCGCGCTCGCGGCGCGCGGCAAGACGTCGACAC
GCAGCGTCGACCCGGCCGAGGTGCAGCGCGAGCTGCTGCGCCAGGGCGTCAACCTGCGCGAGCTTTCGCTTTTTTGA

Upstream 100 bases:

>100_bases
CAGATCGACCGCGCGCTGCCCACGCTGCAGGGCGCGGCGCGCCAGACCCACGAACTCATGCTTCGCGTACTGCGCGGGGA
AGACTGAAAGGAGCCTCGCA

Downstream 100 bases:

>100_bases
CGCCCGCGGCCGCGCGCGTCCGGGAACCTTGGCGCAGAAAGACGTTCTCGCTAGCTATAGTGAATCGACAAAGTTCATAA
GGAGGGGAGGATGCGTGCGT

Product: hypothetical protein

Products: H+; Nicotinamide adenine dinucleotide; Nicotinamide adenine dinucleotide phosphate - reduced [C]

Alternate protein names: Invasion Protein IbeA; Glucose-Inhibited Division Protein A; Fumarate Reductase/Succinate Dehydrogenase Flavoprotein; Dihydrolipoamide Dehydrogenase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Thiamine Biosynthesis Thi4 Protein; Invasion Protein IbeA Family Protein; Protein Involved In Invasion; FAD Dependent Oxidoreductase Domain Protein; Invasion Protein; Pyridine Nucleotide-Disulfide Oxidoreductase Family; tRNA Uridine 5-Carboxymethylaminomethyl GidA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MPVLHRPEQALTVTLPPRSAQVAADCDVLVVGGGPAGIGAALGAAAAGARTVLVERYGFLGGNATAALVMPLMSFHTSRP
QIEQSGAHTLLPTDHGPGTPVIAGAVRQFIARLLAHGGAVPPDLSTGYTVPFDPELFKLTALELLDEAGVSFLFHAFASG
VLGEGRCGGVVFETKGGPQVVRARMIVDATGDGDIAVAAGAPYEIGREADGMVQPMTLMFRVADFERVGFETYVAAHPDQ
WRGVHGLWDLVARATAAGDLDLPREDILLFATPHLHEVSVNSTRVTAHDRRLLGSDPFDLSYAEWVSRGQMRQVAAFLRK
YVPGFEESYAVQSGVQIGVRETRRIRGDYRLSADDVLTARKFGDVIARSTYPIDIHNATGTGTVLKRLPPNEAYDIPLRC
LLPQGLDNVLTAGRCISGDSEAHSSYRVMVVCMATGQAAGACAALAARGKTSTRSVDPAEVQRELLRQGVNLRELSLF

Sequences:

>Translated_478_residues
MPVLHRPEQALTVTLPPRSAQVAADCDVLVVGGGPAGIGAALGAAAAGARTVLVERYGFLGGNATAALVMPLMSFHTSRP
QIEQSGAHTLLPTDHGPGTPVIAGAVRQFIARLLAHGGAVPPDLSTGYTVPFDPELFKLTALELLDEAGVSFLFHAFASG
VLGEGRCGGVVFETKGGPQVVRARMIVDATGDGDIAVAAGAPYEIGREADGMVQPMTLMFRVADFERVGFETYVAAHPDQ
WRGVHGLWDLVARATAAGDLDLPREDILLFATPHLHEVSVNSTRVTAHDRRLLGSDPFDLSYAEWVSRGQMRQVAAFLRK
YVPGFEESYAVQSGVQIGVRETRRIRGDYRLSADDVLTARKFGDVIARSTYPIDIHNATGTGTVLKRLPPNEAYDIPLRC
LLPQGLDNVLTAGRCISGDSEAHSSYRVMVVCMATGQAAGACAALAARGKTSTRSVDPAEVQRELLRQGVNLRELSLF
>Mature_477_residues
PVLHRPEQALTVTLPPRSAQVAADCDVLVVGGGPAGIGAALGAAAAGARTVLVERYGFLGGNATAALVMPLMSFHTSRPQ
IEQSGAHTLLPTDHGPGTPVIAGAVRQFIARLLAHGGAVPPDLSTGYTVPFDPELFKLTALELLDEAGVSFLFHAFASGV
LGEGRCGGVVFETKGGPQVVRARMIVDATGDGDIAVAAGAPYEIGREADGMVQPMTLMFRVADFERVGFETYVAAHPDQW
RGVHGLWDLVARATAAGDLDLPREDILLFATPHLHEVSVNSTRVTAHDRRLLGSDPFDLSYAEWVSRGQMRQVAAFLRKY
VPGFEESYAVQSGVQIGVRETRRIRGDYRLSADDVLTARKFGDVIARSTYPIDIHNATGTGTVLKRLPPNEAYDIPLRCL
LPQGLDNVLTAGRCISGDSEAHSSYRVMVVCMATGQAAGACAALAARGKTSTRSVDPAEVQRELLRQGVNLRELSLF

Specific function: Conversion Of NADPH, Generated By Peripheral Catabolic Pathways, To NADH, Which Can Enter The Respiratory Chain For Energy Generation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.1.1 [C]

Molecular weight: Translated: 50898; Mature: 50766

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00338 SOMATOTROPIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLHRPEQALTVTLPPRSAQVAADCDVLVVGGGPAGIGAALGAAAAGARTVLVERYGFL
CCCCCCCCCEEEEEECCCCCCEECCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCC
GGNATAALVMPLMSFHTSRPQIEQSGAHTLLPTDHGPGTPVIAGAVRQFIARLLAHGGAV
CCCHHHHHHHHHHHHCCCCCCHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
PPDLSTGYTVPFDPELFKLTALELLDEAGVSFLFHAFASGVLGEGRCGGVVFETKGGPQV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHH
VRARMIVDATGDGDIAVAAGAPYEIGREADGMVQPMTLMFRVADFERVGFETYVAAHPDQ
EEEEEEEEECCCCCEEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHH
WRGVHGLWDLVARATAAGDLDLPREDILLFATPHLHEVSVNSTRVTAHDRRLLGSDPFDL
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEECCCEEEEHHHHHHCCCCCCCC
SYAEWVSRGQMRQVAAFLRKYVPGFEESYAVQSGVQIGVRETRRIRGDYRLSADDVLTAR
CHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHCCCEECHHHHHHHCCCEEECHHHHHHHH
KFGDVIARSTYPIDIHNATGTGTVLKRLPPNEAYDIPLRCLLPQGLDNVLTAGRCISGDS
HHHHHHHCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCEEECCCCHHHHHHCCCCCCCCC
EAHSSYRVMVVCMATGQAAGACAALAARGKTSTRSVDPAEVQRELLRQGVNLRELSLF
CCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
PVLHRPEQALTVTLPPRSAQVAADCDVLVVGGGPAGIGAALGAAAAGARTVLVERYGFL
CCCCCCCCEEEEEECCCCCCEECCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCC
GGNATAALVMPLMSFHTSRPQIEQSGAHTLLPTDHGPGTPVIAGAVRQFIARLLAHGGAV
CCCHHHHHHHHHHHHCCCCCCHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
PPDLSTGYTVPFDPELFKLTALELLDEAGVSFLFHAFASGVLGEGRCGGVVFETKGGPQV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHH
VRARMIVDATGDGDIAVAAGAPYEIGREADGMVQPMTLMFRVADFERVGFETYVAAHPDQ
EEEEEEEEECCCCCEEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHH
WRGVHGLWDLVARATAAGDLDLPREDILLFATPHLHEVSVNSTRVTAHDRRLLGSDPFDL
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEECCCEEEEHHHHHHCCCCCCCC
SYAEWVSRGQMRQVAAFLRKYVPGFEESYAVQSGVQIGVRETRRIRGDYRLSADDVLTAR
CHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHCCCEECHHHHHHHCCCEEECHHHHHHHH
KFGDVIARSTYPIDIHNATGTGTVLKRLPPNEAYDIPLRCLLPQGLDNVLTAGRCISGDS
HHHHHHHCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCEEECCCCHHHHHHCCCCCCCCC
EAHSSYRVMVVCMATGQAAGACAALAARGKTSTRSVDPAEVQRELLRQGVNLRELSLF
CCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 2'-AMP; FAD; p-Hydroxymercuribenzoate [C]

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H+; Nicotinamide adenine dinucleotide - reduced; Nicotinamide adenine dinucleotide phosphate [C]

Specific reaction: (2) H+ (Extracellular) + Nicotinamide adenine dinucleotide - reduced + Nicotinamide adenine dinucleotide phosphate --> (2) H+ + Nicotinamide adenine dinucleotide + Nicotinamide adenine dinucleotide phosphate - reduced [C]

General reaction: Redox reaction [C]

Inhibitor: p-Hydroxy mercuribenzoate reducedsubstrate, [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA