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The map label for this gene is csgA [H]

Identifier: 74317487

GI number: 74317487

Start: 1553511

End: 1554215

Strand: Reverse

Name: csgA [H]

Synonym: Tbd_1469

Alternate gene names: 74317487

Gene position: 1554215-1553511 (Counterclockwise)

Preceding gene: 74317491

Following gene: 74317484

Centisome position: 53.41

GC content: 67.66

Gene sequence:

>705_bases
ATGCGACCCCGCCAGACCGTCCTGATCACCGGCGCGAGCCGGGGCCTCGGGCTCGAATGGGCGCGGCAGTATGCCGAAGA
CGGCTGGGGCGTGTGCGCGACCTGCCGCCGCCCGGAAGAGGCGCGCGAACTGACGGCGCTCGCGGCGCAGCATCGCGATG
TCAGCGTGCACCGGCTCGACGTGACCGATGCCGAGCAACTGCGCACGCTGCAACTCGATCTCGAAGAGGCGTGCATCGAC
GTGCTGCTCAACAACGCGGGCGTCTACCTCGACAAGTTCCTTGGCGACTTCGGCGGCATCGACTACGAAGTCTGGTTGCG
CAGCTTCGCCGTCAACACGCTCGGTGCCGTTCGCGTCAGCGAGGCGTTCGCCGCGCAGGTCGCGCGCAGCGAGAAGAAGC
TCGTCGTCGTGACCACGAGCCACATGGGATCGATCACCGACATCAGCGCGCCGGGCAGCTACGCCTACCGCTCGAGCAAG
GCGGCCTTGAACGCCGCGATGAAGGGCATCGCGCCGGCACTCGAGCCGCGCGGCATCGGCCTCCTGCTGCTGCATCCGGG
CTGGGTCAAAACGCGCATGGGCGGCCGCGACGCGCCGTATACGCCCGAACAGAGCGTTCGCGGCATGCGCCGTCTGGTCG
AGAAATTCGACCCGTCGATGAACGCGCGTTTCTTCCGTTTCGACGGCAGCGAAATGCCCTGGTAG

Upstream 100 bases:

>100_bases
AGTTAAGACGATGCCTCGCGCAAAGTGAAGCCCGACGCGGCTTCGCGCGCGGTTGTCTATCCGCGGTCTATAAAGATTCC
ATGACAGCGAGACCACGACG

Downstream 100 bases:

>100_bases
TCAGTCGCGCACCACAACCACGAGCGGGACCCGCATTTCTGCCGCCGACGCGCCGCCGTGCACGCCGAGATGGGCATGGC
GCACTTCGCCGAGCAGCCAG

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRPRQTVLITGASRGLGLEWARQYAEDGWGVCATCRRPEEARELTALAAQHRDVSVHRLDVTDAEQLRTLQLDLEEACID
VLLNNAGVYLDKFLGDFGGIDYEVWLRSFAVNTLGAVRVSEAFAAQVARSEKKLVVVTTSHMGSITDISAPGSYAYRSSK
AALNAAMKGIAPALEPRGIGLLLLHPGWVKTRMGGRDAPYTPEQSVRGMRRLVEKFDPSMNARFFRFDGSEMPW

Sequences:

>Translated_234_residues
MRPRQTVLITGASRGLGLEWARQYAEDGWGVCATCRRPEEARELTALAAQHRDVSVHRLDVTDAEQLRTLQLDLEEACID
VLLNNAGVYLDKFLGDFGGIDYEVWLRSFAVNTLGAVRVSEAFAAQVARSEKKLVVVTTSHMGSITDISAPGSYAYRSSK
AALNAAMKGIAPALEPRGIGLLLLHPGWVKTRMGGRDAPYTPEQSVRGMRRLVEKFDPSMNARFFRFDGSEMPW
>Mature_234_residues
MRPRQTVLITGASRGLGLEWARQYAEDGWGVCATCRRPEEARELTALAAQHRDVSVHRLDVTDAEQLRTLQLDLEEACID
VLLNNAGVYLDKFLGDFGGIDYEVWLRSFAVNTLGAVRVSEAFAAQVARSEKKLVVVTTSHMGSITDISAPGSYAYRSSK
AALNAAMKGIAPALEPRGIGLLLLHPGWVKTRMGGRDAPYTPEQSVRGMRRLVEKFDPSMNARFFRFDGSEMPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=199, Percent_Identity=34.1708542713568, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI32483357, Length=193, Percent_Identity=29.0155440414508, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI223718074, Length=195, Percent_Identity=32.3076923076923, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=28.7958115183246, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558990, Length=263, Percent_Identity=29.277566539924, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17558994, Length=247, Percent_Identity=31.1740890688259, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17559962, Length=257, Percent_Identity=28.4046692607004, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17558992, Length=244, Percent_Identity=31.9672131147541, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17532177, Length=252, Percent_Identity=28.1746031746032, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559964, Length=257, Percent_Identity=28.0155642023346, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193207563, Length=253, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17542178, Length=246, Percent_Identity=27.6422764227642, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322779, Length=250, Percent_Identity=27.2, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=222, Percent_Identity=26.1261261261261, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640547, Length=248, Percent_Identity=30.6451612903226, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24643142, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25872; Mature: 25872

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRQTVLITGASRGLGLEWARQYAEDGWGVCATCRRPEEARELTALAAQHRDVSVHRLD
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEC
VTDAEQLRTLQLDLEEACIDVLLNNAGVYLDKFLGDFGGIDYEVWLRSFAVNTLGAVRVS
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
EAFAAQVARSEKKLVVVTTSHMGSITDISAPGSYAYRSSKAALNAAMKGIAPALEPRGIG
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
LLLLHPGWVKTRMGGRDAPYTPEQSVRGMRRLVEKFDPSMNARFFRFDGSEMPW
EEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRPRQTVLITGASRGLGLEWARQYAEDGWGVCATCRRPEEARELTALAAQHRDVSVHRLD
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEC
VTDAEQLRTLQLDLEEACIDVLLNNAGVYLDKFLGDFGGIDYEVWLRSFAVNTLGAVRVS
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
EAFAAQVARSEKKLVVVTTSHMGSITDISAPGSYAYRSSKAALNAAMKGIAPALEPRGIG
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
LLLLHPGWVKTRMGGRDAPYTPEQSVRGMRRLVEKFDPSMNARFFRFDGSEMPW
EEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]