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The map label for this gene is 74317444

Identifier: 74317444

GI number: 74317444

Start: 1515546

End: 1516646

Strand: Direct

Name: 74317444

Synonym: Tbd_1426

Alternate gene names: NA

Gene position: 1515546-1516646 (Clockwise)

Preceding gene: 74317443

Following gene: 74317445

Centisome position: 52.08

GC content: 66.39

Gene sequence:

>1101_bases
ATGAGTGCGCAGTGTGAAGTCACCGCCAAGCGCGCGGCCGCCATGGGCGGCCCGCCGGCGCCGATGAGCGTGTTCGAGCG
CTGGCTCACCCTGTGGGTCGCGCTGTGCATCGTCGCCGGCGTGGCACTCGGGCAACTGTTCCCGGCGCCATTCCAGGCGC
TCGGGCGGATGGAGGTGGCGCAGGTCAATCTGCCGGTCGGCCTGTTGATCTGGATCATGATCATCCCGATGCTGATGAAG
ATCGACTTCGGCGCGCTGCATCAGGTGAAATCGCACTGGCGCGGCATCGGCGTCACGCTCTTCGTCAACTGGGCGGTGAA
GCCGTTCTCGATGGCACTCCTGGCGTGGATCTTCATCCGCCATTTGTTCGCGCCCTGGCTGCCCGCCGAGCAGCTCGACA
GCTACGTCGCCGGCCTGATCCTGCTCGCGGCCGCGCCGTGCACGGCGATGGTGTTCGTGTGGAGCCGCCTGACCGGCGGC
GATCCATATTTCACGCTGTCGCAGGTGGCGCTCAACGACACCATCATGATCTTCGCCTTCGCGCCGATCATCGGGCTGCT
CCTGGGCCTTTCCGCGATCGTGGTGCCGTGGGACACGCTCATGATTTCGGTCGCGCTTTATATCGTGCTTCCGGTGATCC
TCGCGCAGGTCTGGCGCAAGCGGCTGCTGAAGCGCGGGCAGGCGGTGTTCGACCGGGTGATGGCGCAGCTCGGCCAGGCT
TCGATCCTCGCGCTGCTGGCGACGCTGGTGCTGCTGTTCGCCTTTCAGGGCGAGCAGATCCTCGCGCAGCCGTTGATCAT
CGCGTTGCTCGCAGTGCCGATCCTGATCCAGGTCTTCTTCAACTCGGGCTTGGCCTACTGGCTGAACAGAAAAGTGGGCG
AGAAGCACGCCGTCGCCTGCCCGTCGGCGCTGATCGGCGCGTCGAACTTCTTCGAGCTGGCGGTGGCGGCGGCGATCGCG
CTGTTCGGCTTCGAGTCGGGCGCGGCGCTGGCGACCGTGGTCGGCGTGCTGATCGAGGTGCCGGTGATGCTGCTGGTGGT
GAAGCTCGTCAACCGCAGCAAGCGCTGGTACGAGCGCGGCCTGCCAGCGGGACGGGCCTGA

Upstream 100 bases:

>100_bases
ACCGCTCGAGAGCTTCATCGCCGTACGCGACGACATCCGCACGCGCCTCGTCGCGGCGGTGCGCGAGAAACTCGGCCTCG
CGGCCGCGGCCTGAACGTCC

Downstream 100 bases:

>100_bases
GCTGAGGCGCAATCGTGTTCGACGCACTCGCCACCCTGCTGGTTTTCGACCTCGCCGGCCTGACGCCGGGCACGCCGCTG
GGCCAAGCGCTGCATTTCTT

Product: ACR3 family arsenite transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSAQCEVTAKRAAAMGGPPAPMSVFERWLTLWVALCIVAGVALGQLFPAPFQALGRMEVAQVNLPVGLLIWIMIIPMLMK
IDFGALHQVKSHWRGIGVTLFVNWAVKPFSMALLAWIFIRHLFAPWLPAEQLDSYVAGLILLAAAPCTAMVFVWSRLTGG
DPYFTLSQVALNDTIMIFAFAPIIGLLLGLSAIVVPWDTLMISVALYIVLPVILAQVWRKRLLKRGQAVFDRVMAQLGQA
SILALLATLVLLFAFQGEQILAQPLIIALLAVPILIQVFFNSGLAYWLNRKVGEKHAVACPSALIGASNFFELAVAAAIA
LFGFESGAALATVVGVLIEVPVMLLVVKLVNRSKRWYERGLPAGRA

Sequences:

>Translated_366_residues
MSAQCEVTAKRAAAMGGPPAPMSVFERWLTLWVALCIVAGVALGQLFPAPFQALGRMEVAQVNLPVGLLIWIMIIPMLMK
IDFGALHQVKSHWRGIGVTLFVNWAVKPFSMALLAWIFIRHLFAPWLPAEQLDSYVAGLILLAAAPCTAMVFVWSRLTGG
DPYFTLSQVALNDTIMIFAFAPIIGLLLGLSAIVVPWDTLMISVALYIVLPVILAQVWRKRLLKRGQAVFDRVMAQLGQA
SILALLATLVLLFAFQGEQILAQPLIIALLAVPILIQVFFNSGLAYWLNRKVGEKHAVACPSALIGASNFFELAVAAAIA
LFGFESGAALATVVGVLIEVPVMLLVVKLVNRSKRWYERGLPAGRA
>Mature_365_residues
SAQCEVTAKRAAAMGGPPAPMSVFERWLTLWVALCIVAGVALGQLFPAPFQALGRMEVAQVNLPVGLLIWIMIIPMLMKI
DFGALHQVKSHWRGIGVTLFVNWAVKPFSMALLAWIFIRHLFAPWLPAEQLDSYVAGLILLAAAPCTAMVFVWSRLTGGD
PYFTLSQVALNDTIMIFAFAPIIGLLLGLSAIVVPWDTLMISVALYIVLPVILAQVWRKRLLKRGQAVFDRVMAQLGQAS
ILALLATLVLLFAFQGEQILAQPLIIALLAVPILIQVFFNSGLAYWLNRKVGEKHAVACPSALIGASNFFELAVAAAIAL
FGFESGAALATVVGVLIEVPVMLLVVKLVNRSKRWYERGLPAGRA

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=336, Percent_Identity=24.1071428571429, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39766; Mature: 39634

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
SAQCEVTAKRAAAMGGPPAPMSVFERWLTLWVALCIVAGVALGQLFPAPFQALGRMEVA
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHH
QVNLPVGLLIWIMIIPMLMKIDFGALHQVKSHWRGIGVTLFVNWAVKPFSMALLAWIFIR
HCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
HLFAPWLPAEQLDSYVAGLILLAAAPCTAMVFVWSRLTGGDPYFTLSQVALNDTIMIFAF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
APIIGLLLGLSAIVVPWDTLMISVALYIVLPVILAQVWRKRLLKRGQAVFDRVMAQLGQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
SILALLATLVLLFAFQGEQILAQPLIIALLAVPILIQVFFNSGLAYWLNRKVGEKHAVAC
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHC
PSALIGASNFFELAVAAAIALFGFESGAALATVVGVLIEVPVMLLVVKLVNRSKRWYERG
CHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPAGRA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]