Click here to switch to the map view.

The map label for this gene is arsC2 [H]

Identifier: 74317443

GI number: 74317443

Start: 1515114

End: 1515539

Strand: Direct

Name: arsC2 [H]

Synonym: Tbd_1425

Alternate gene names: 74317443

Gene position: 1515114-1515539 (Clockwise)

Preceding gene: 74317442

Following gene: 74317444

Centisome position: 52.07

GC content: 67.61

Gene sequence:

>426_bases
ATGACCAAACCCCTGACCGTGCTGGTGCTGTGCACCGGCAACTCCTGCCGCTCGCAAATGGCCGAGGTGCTGCTCAACCA
TGACCTCGCGGGCCAGGTGCGCGCACTCTCCGCCGGCACCCGGCCGCAACCGAAGGTCGCGGACGGGGCGATCGCGGCGC
TGCAAGCGGCCGGACTGAATACCGACGGTCTCCATCCGAAGGACGTCGATGCGGTGATGCACGAGGACATCGACCTCGTC
GTGACCGTGTGCGACAACGCGAAGGAGGCCTGCCCGATCTTTCCCAAGCCGATTCCGGCGATCCATCTTCCCTTCCATGA
CCCGCACGGCGAACCGCTCGAGAGCTTCATCGCCGTACGCGACGACATCCGCACGCGCCTCGTCGCGGCGGTGCGCGAGA
AACTCGGCCTCGCGGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
ACACGCCCGCCTGCACGGGCGGCGGGTCGTCGTAACGAATTCACGTCACACCGCGCGGCCAAGCTCCGGCTGTTTCATCA
CGTTTCGACAAGGACTACTC

Downstream 100 bases:

>100_bases
ACGTCCATGAGTGCGCAGTGTGAAGTCACCGCCAAGCGCGCGGCCGCCATGGGCGGCCCGCCGGCGCCGATGAGCGTGTT
CGAGCGCTGGCTCACCCTGT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase 2; Arsenical pump modifier 2; Low molecular weight protein-tyrosine-phosphatase 2 [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MTKPLTVLVLCTGNSCRSQMAEVLLNHDLAGQVRALSAGTRPQPKVADGAIAALQAAGLNTDGLHPKDVDAVMHEDIDLV
VTVCDNAKEACPIFPKPIPAIHLPFHDPHGEPLESFIAVRDDIRTRLVAAVREKLGLAAAA

Sequences:

>Translated_141_residues
MTKPLTVLVLCTGNSCRSQMAEVLLNHDLAGQVRALSAGTRPQPKVADGAIAALQAAGLNTDGLHPKDVDAVMHEDIDLV
VTVCDNAKEACPIFPKPIPAIHLPFHDPHGEPLESFIAVRDDIRTRLVAAVREKLGLAAAA
>Mature_140_residues
TKPLTVLVLCTGNSCRSQMAEVLLNHDLAGQVRALSAGTRPQPKVADGAIAALQAAGLNTDGLHPKDVDAVMHEDIDLVV
TVCDNAKEACPIFPKPIPAIHLPFHDPHGEPLESFIAVRDDIRTRLVAAVREKLGLAAAA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 14925; Mature: 14794

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPLTVLVLCTGNSCRSQMAEVLLNHDLAGQVRALSAGTRPQPKVADGAIAALQAAGLN
CCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCC
TDGLHPKDVDAVMHEDIDLVVTVCDNAKEACPIFPKPIPAIHLPFHDPHGEPLESFIAVR
CCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
DDIRTRLVAAVREKLGLAAAA
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKPLTVLVLCTGNSCRSQMAEVLLNHDLAGQVRALSAGTRPQPKVADGAIAALQAAGLN
CCCEEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCC
TDGLHPKDVDAVMHEDIDLVVTVCDNAKEACPIFPKPIPAIHLPFHDPHGEPLESFIAVR
CCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
DDIRTRLVAAVREKLGLAAAA
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA