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The map label for this gene is macB [H]

Identifier: 74317430

GI number: 74317430

Start: 1499056

End: 1500258

Strand: Reverse

Name: macB [H]

Synonym: Tbd_1412

Alternate gene names: 74317430

Gene position: 1500258-1499056 (Counterclockwise)

Preceding gene: 74317431

Following gene: 74317429

Centisome position: 51.56

GC content: 65.59

Gene sequence:

>1203_bases
ATGCTCTGGAACACGCTGCTGCTGGCCCTGCGCGCGATCCGGCGCAACCTGATGCGCTCGTTCCTGACCGTGCTCGGCAT
CGTGATCGGGGTCGCCGCCGTCGTCATCATGGTGACCCTCGGCAACGGCGCGACGCGTTCGGTATCGGACCAGATTTCGA
GCATGGGCAGCAATCTGCTGATGGTTCGGCCGGGGCAGCGCTACGGCCCCGGAGCCGAAGCTGCACCCAATTTCAAGCTC
GCCGACGCCGAGGCGATCCGCAACCAGATCTCGGCGGCCGAGGCGGTCGCACCGGTCGTCAGCATGAGCGTGACCGCGGT
GTACCAGGTGCGGAACTGGTCGACGGTCGTCACCGGCTCCAACAACGATTATTTCGCCGCGGGAAACTGGGAAATCGCAG
CGGGCCGCAGCTTCAACGACGCCGAGGAACGCGCCGGCAAGGCCGTCTGCGTGATCGGCGAGTCGGTGCGCGAAAAGCTT
TTCGGCGGGCAGAACCCGGTCGGCAGCGACATCCGCATCAAGCAGTTTTCCTGCGAAGTCATCGGCCTTCTGAAGCCCAA
GGGCCAGTCGGCGATGGGCTCGGATCAGGACGACACGATCGTGATGCCGCTGCGCACGGTCCAGCGCCGCCTCGCGGGCA
GCCAGGACGTCAATCGCCTGAGCGTCTCGGTCCGCGCCGGTGCGTCGATCGATGTTGCCAAGGACCAACTCACGCTGCTG
CTGCGCGAACGGCGCGGCATCGCCGACAACGAGGAGGACGATTTTCGCGTGATGGACACGCGCCAGATCGCCGAAACCCT
GACCGGCACGACGCGGGTGCTGACCATGCTGCTCGGCGCCGTCGCCGCGGTGAGTCTGCTCGTCGGCGGCATCGGCATCA
TGAACATCATGCTCGTGTCGGTCACCGAGCGCACGCGCGAAATCGGCATCCGCCTCGCCATCGGCGCGCTCGAACGCGAA
GTCCTGCTGCAATTCCTGATCGAAGCCGTGGTGCTGGCGAGCCTCGGCGGACTCGTCGGCATCGCGATCGCGACGGCCAC
CTCGATCTTTCTCGCCGGCATGATGGGCATCCTCTACCTGTTCGATCCCGCCATCAACCTGTTGTCGTTTTTCTTTTCGG
CCGCGATCGGTGTGGTCTTCGGCTACTTCCCGGCACGGCGTGCCGCGGGCCTCAATCCGATCGACGCCTTGCGCCACGAA
TAG

Upstream 100 bases:

>100_bases
TGGTGACGCACGAGCCGGAGATGGCAGCGTACGCGCGCCGCGCGATCCGTTTCGTCGACGGCCGTGTGGCCAGCGACGGC
AGCGGGCACGGGGACGCCTG

Downstream 100 bases:

>100_bases
CCCCGCCACTTGCGGGAAGTCCGATGCCGATTGGAATTTCTTTGGAAACATGGCGTTGGAACGGTATTCTTTGCAATCCG
TTTGAGTGTTCAGGCGGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLWNTLLLALRAIRRNLMRSFLTVLGIVIGVAAVVIMVTLGNGATRSVSDQISSMGSNLLMVRPGQRYGPGAEAAPNFKL
ADAEAIRNQISAAEAVAPVVSMSVTAVYQVRNWSTVVTGSNNDYFAAGNWEIAAGRSFNDAEERAGKAVCVIGESVREKL
FGGQNPVGSDIRIKQFSCEVIGLLKPKGQSAMGSDQDDTIVMPLRTVQRRLAGSQDVNRLSVSVRAGASIDVAKDQLTLL
LRERRGIADNEEDDFRVMDTRQIAETLTGTTRVLTMLLGAVAAVSLLVGGIGIMNIMLVSVTERTREIGIRLAIGALERE
VLLQFLIEAVVLASLGGLVGIAIATATSIFLAGMMGILYLFDPAINLLSFFFSAAIGVVFGYFPARRAAGLNPIDALRHE

Sequences:

>Translated_400_residues
MLWNTLLLALRAIRRNLMRSFLTVLGIVIGVAAVVIMVTLGNGATRSVSDQISSMGSNLLMVRPGQRYGPGAEAAPNFKL
ADAEAIRNQISAAEAVAPVVSMSVTAVYQVRNWSTVVTGSNNDYFAAGNWEIAAGRSFNDAEERAGKAVCVIGESVREKL
FGGQNPVGSDIRIKQFSCEVIGLLKPKGQSAMGSDQDDTIVMPLRTVQRRLAGSQDVNRLSVSVRAGASIDVAKDQLTLL
LRERRGIADNEEDDFRVMDTRQIAETLTGTTRVLTMLLGAVAAVSLLVGGIGIMNIMLVSVTERTREIGIRLAIGALERE
VLLQFLIEAVVLASLGGLVGIAIATATSIFLAGMMGILYLFDPAINLLSFFFSAAIGVVFGYFPARRAAGLNPIDALRHE
>Mature_400_residues
MLWNTLLLALRAIRRNLMRSFLTVLGIVIGVAAVVIMVTLGNGATRSVSDQISSMGSNLLMVRPGQRYGPGAEAAPNFKL
ADAEAIRNQISAAEAVAPVVSMSVTAVYQVRNWSTVVTGSNNDYFAAGNWEIAAGRSFNDAEERAGKAVCVIGESVREKL
FGGQNPVGSDIRIKQFSCEVIGLLKPKGQSAMGSDQDDTIVMPLRTVQRRLAGSQDVNRLSVSVRAGASIDVAKDQLTLL
LRERRGIADNEEDDFRVMDTRQIAETLTGTTRVLTMLLGAVAAVSLLVGGIGIMNIMLVSVTERTREIGIRLAIGALERE
VLLQFLIEAVVLASLGGLVGIAIATATSIFLAGMMGILYLFDPAINLLSFFFSAAIGVVFGYFPARRAAGLNPIDALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=404, Percent_Identity=39.1089108910891, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42741; Mature: 42741

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWNTLLLALRAIRRNLMRSFLTVLGIVIGVAAVVIMVTLGNGATRSVSDQISSMGSNLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEE
MVRPGQRYGPGAEAAPNFKLADAEAIRNQISAAEAVAPVVSMSVTAVYQVRNWSTVVTGS
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEECC
NNDYFAAGNWEIAAGRSFNDAEERAGKAVCVIGESVREKLFGGQNPVGSDIRIKQFSCEV
CCCEEEECCEEEECCCCCCHHHHHCCCEEEEECHHHHHHHCCCCCCCCCCEEEEEECCEE
IGLLKPKGQSAMGSDQDDTIVMPLRTVQRRLAGSQDVNRLSVSVRAGASIDVAKDQLTLL
EEEECCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCHHEEEEEECCCCCCHHHHHHHHH
LRERRGIADNEEDDFRVMDTRQIAETLTGTTRVLTMLLGAVAAVSLLVGGIGIMNIMLVS
HHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTERTREIGIRLAIGALEREVLLQFLIEAVVLASLGGLVGIAIATATSIFLAGMMGILYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDPAINLLSFFFSAAIGVVFGYFPARRAAGLNPIDALRHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MLWNTLLLALRAIRRNLMRSFLTVLGIVIGVAAVVIMVTLGNGATRSVSDQISSMGSNLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEE
MVRPGQRYGPGAEAAPNFKLADAEAIRNQISAAEAVAPVVSMSVTAVYQVRNWSTVVTGS
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEECC
NNDYFAAGNWEIAAGRSFNDAEERAGKAVCVIGESVREKLFGGQNPVGSDIRIKQFSCEV
CCCEEEECCEEEECCCCCCHHHHHCCCEEEEECHHHHHHHCCCCCCCCCCEEEEEECCEE
IGLLKPKGQSAMGSDQDDTIVMPLRTVQRRLAGSQDVNRLSVSVRAGASIDVAKDQLTLL
EEEECCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCHHEEEEEECCCCCCHHHHHHHHH
LRERRGIADNEEDDFRVMDTRQIAETLTGTTRVLTMLLGAVAAVSLLVGGIGIMNIMLVS
HHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTERTREIGIRLAIGALEREVLLQFLIEAVVLASLGGLVGIAIATATSIFLAGMMGILYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDPAINLLSFFFSAAIGVVFGYFPARRAAGLNPIDALRHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA