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The map label for this gene is hupD [H]

Identifier: 74317398

GI number: 74317398

Start: 1460268

End: 1460738

Strand: Reverse

Name: hupD [H]

Synonym: Tbd_1380

Alternate gene names: 74317398

Gene position: 1460738-1460268 (Counterclockwise)

Preceding gene: 74317405

Following gene: 74317397

Centisome position: 50.2

GC content: 69.0

Gene sequence:

>471_bases
ATGAAAACGCTCGTGCTCGGCATCGGCAACACATTGCTTACCGACGAAGGCGTCGGCGTCCACCTGCTCGACGTCCTTCG
CCCCATGCTCGGCGACCTGCACGGCGTCACGCTGCTCGACGGCGGCACGCTGTCGTTCACACTTGCCGCGTCGATTGAGG
ATGCCGACGCGCTGATCGTCGTCGACGCGGCCGAGCTGAAACGCCGCCCGGGCGAATGGGCGGTGCTGGAAGGGGAGGAG
ATGGACCGGTTCCTGATAGGCGCGCGCAAAGCTTCGGTGCACGAAGTGGGCCTCGCCGACCTGCGCACCATCGCGCTCCT
TGCGGGCCACTGGCCGGAACGACGTGCGCTGCTCGCGATCCAGCCCGCGGTCATCGACTGGGGCGAATTCCCCACGGCCC
CGGTCGCGGCCGCCATGCCGCCCGCATGCGCGGCGATCGCGCACCTGATCCGGGGCTGGCATGACGCGTGA

Upstream 100 bases:

>100_bases
GGATTTGCCCGGCGGGGCCCAGGACGTAGGGGAGCGTGCCGCCGACCAATGATTGGCGACGATTGCGCTCCGCATAAGCT
CTGGTAGATTGAAAGAGACA

Downstream 100 bases:

>100_bases
AATCATCCCGATCCTCCCCGAGGCGCCCGTCGAAACGGCGCGCTCGGGCAACGCGCTACCGCTCCTGCGCGAAATCGCCG
AACATCTGCACCACCTGCTC

Product: peptidase M52, hydrogen uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKTLVLGIGNTLLTDEGVGVHLLDVLRPMLGDLHGVTLLDGGTLSFTLAASIEDADALIVVDAAELKRRPGEWAVLEGEE
MDRFLIGARKASVHEVGLADLRTIALLAGHWPERRALLAIQPAVIDWGEFPTAPVAAAMPPACAAIAHLIRGWHDA

Sequences:

>Translated_156_residues
MKTLVLGIGNTLLTDEGVGVHLLDVLRPMLGDLHGVTLLDGGTLSFTLAASIEDADALIVVDAAELKRRPGEWAVLEGEE
MDRFLIGARKASVHEVGLADLRTIALLAGHWPERRALLAIQPAVIDWGEFPTAPVAAAMPPACAAIAHLIRGWHDA
>Mature_156_residues
MKTLVLGIGNTLLTDEGVGVHLLDVLRPMLGDLHGVTLLDGGTLSFTLAASIEDADALIVVDAAELKRRPGEWAVLEGEE
MDRFLIGARKASVHEVGLADLRTIALLAGHWPERRALLAIQPAVIDWGEFPTAPVAAAMPPACAAIAHLIRGWHDA

Specific function: Not known. Could be involved in the processing of hydrogenase [H]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1789367, Length=154, Percent_Identity=34.4155844155844, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1787209, Length=126, Percent_Identity=32.5396825396825, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 16577; Mature: 16577

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLVLGIGNTLLTDEGVGVHLLDVLRPMLGDLHGVTLLDGGTLSFTLAASIEDADALIV
CCEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCEEEE
VDAAELKRRPGEWAVLEGEEMDRFLIGARKASVHEVGLADLRTIALLAGHWPERRALLAI
EEHHHHHCCCCCEEEEECCCCCHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCCEEEEE
QPAVIDWGEFPTAPVAAAMPPACAAIAHLIRGWHDA
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTLVLGIGNTLLTDEGVGVHLLDVLRPMLGDLHGVTLLDGGTLSFTLAASIEDADALIV
CCEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCEEEE
VDAAELKRRPGEWAVLEGEEMDRFLIGARKASVHEVGLADLRTIALLAGHWPERRALLAI
EEHHHHHCCCCCEEEEECCCCCHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCCEEEEE
QPAVIDWGEFPTAPVAAAMPPACAAIAHLIRGWHDA
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1597428 [H]