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The map label for this gene is hoxK [H]

Identifier: 74317396

GI number: 74317396

Start: 1458746

End: 1459828

Strand: Reverse

Name: hoxK [H]

Synonym: Tbd_1378

Alternate gene names: 74317396

Gene position: 1459828-1458746 (Counterclockwise)

Preceding gene: 74317397

Following gene: 74317395

Centisome position: 50.17

GC content: 67.5

Gene sequence:

>1083_bases
ATGCAGCAAAGCCCGTTGATCGACATGCTCGGACGGCAAGGGGTCACGCGCCGCGGCTTTCTCAAGTACTGCGCCACGCT
GGCTTCGCTGATGGCCTTGCCGCCCGCGGCGGGCCGGGCGATGGCCGAGGCCATCGGCGCCGTCAGGCGGCCGTCGGTGA
TCTGGCTGCCGTTCCAGGAATGCACCGGTTGCACCGAATCGATCACGCGCTCGCATTCGCCGACCATCGAGGGCCTGATT
TTCGAGGCGATCTCGCTCGACTACCAGGAAACGCTGATGGCCGCCGCAGGGCATCGGGCCGAGGCCGCGCGCGACGCCGC
GATACGCGACAACTTCGGCAAATATCTGCTCGTCGTCGACGGCTCTGTCCCGCTCGGCGCCGAGGGCGCCTATTCGTGCA
TCGGCGGGCGCTCCAACGTCGACATCCTGCGGGAGGCGGCCAAAGGCGCCGCGGCCATCATCTGCGTCGGCACCTGCTCG
TCGTACGGGGGCATTCCCCACGCCAACCCGAATCCGACCGGCGCGGTCGCGGTCTCCGACGTCATCAAGGACAAGCCCAT
CGTCAACATTCCGGGCTGTCCGCCCATCCCGGTCGTCATGACGGGCGTGCTCGCGCATTACATCGCCTTCGGCAGCCTGC
CCGAACTCGACGCGAAGAACCGGCCCAAGGCCTTCTTCGGCGAGACCATCCACGATCGCTGCTATCGCCGGCCTTTCTAC
GACCAGGGCAAATTCGCCAAGACCTTCGACGACGAGGGCGCGCGCAAGGGCTGGTGCCTGTTCGAGCTCGGGTGCAAGGG
TCCGGTCACCCACAACGCCTGCGCGACCGTCAAATGGAATGGCGGCACCTCCTGGCCGGTCGAGTCGGGCCACGGCTGCC
TCGGATGTTCCGAGCCCGACTTCTGGGACGCCGGCAGCTTCTACAAGGCATTGTCGCAGCCTTCCGGGCCGCTGAACGTC
GGACTCGCCGCGACAGCTGGCGGGCTCGCGACCGGCGCCGCCGTCACGGTCGCCAACCGCGCGAAGAAAAGCGCGGCGCG
GGCGTCGCACAGGACGATCACGGTCGAGGATCTGGAGAAATGA

Upstream 100 bases:

>100_bases
GCCGCGCGCGGACGTCGCAGCGGCCCGCGCGGCCCTTGTCTTGCGGATGGCGGACCTCTAAGGTGAAGGAGCCGCCAAAG
CCTCGGCTCAGGAGACACGC

Downstream 100 bases:

>100_bases
ACGAACTGGAGCTTCTGACCTGGCTGCGCGGACCCGGCCTTGCGATTTCGGCCGGCATCTTTCTCGCTGGCGTGCTCTGG
CGCCTGCTCGAGGTCTTCCT

Product: Ni-Fe hydrogenase, small subunit

Products: NA

Alternate protein names: Hydrogenase subunit beta; Hydrogenlyase; Membrane-bound hydrogenase small subunit [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MQQSPLIDMLGRQGVTRRGFLKYCATLASLMALPPAAGRAMAEAIGAVRRPSVIWLPFQECTGCTESITRSHSPTIEGLI
FEAISLDYQETLMAAAGHRAEAARDAAIRDNFGKYLLVVDGSVPLGAEGAYSCIGGRSNVDILREAAKGAAAIICVGTCS
SYGGIPHANPNPTGAVAVSDVIKDKPIVNIPGCPPIPVVMTGVLAHYIAFGSLPELDAKNRPKAFFGETIHDRCYRRPFY
DQGKFAKTFDDEGARKGWCLFELGCKGPVTHNACATVKWNGGTSWPVESGHGCLGCSEPDFWDAGSFYKALSQPSGPLNV
GLAATAGGLATGAAVTVANRAKKSAARASHRTITVEDLEK

Sequences:

>Translated_360_residues
MQQSPLIDMLGRQGVTRRGFLKYCATLASLMALPPAAGRAMAEAIGAVRRPSVIWLPFQECTGCTESITRSHSPTIEGLI
FEAISLDYQETLMAAAGHRAEAARDAAIRDNFGKYLLVVDGSVPLGAEGAYSCIGGRSNVDILREAAKGAAAIICVGTCS
SYGGIPHANPNPTGAVAVSDVIKDKPIVNIPGCPPIPVVMTGVLAHYIAFGSLPELDAKNRPKAFFGETIHDRCYRRPFY
DQGKFAKTFDDEGARKGWCLFELGCKGPVTHNACATVKWNGGTSWPVESGHGCLGCSEPDFWDAGSFYKALSQPSGPLNV
GLAATAGGLATGAAVTVANRAKKSAARASHRTITVEDLEK
>Mature_360_residues
MQQSPLIDMLGRQGVTRRGFLKYCATLASLMALPPAAGRAMAEAIGAVRRPSVIWLPFQECTGCTESITRSHSPTIEGLI
FEAISLDYQETLMAAAGHRAEAARDAAIRDNFGKYLLVVDGSVPLGAEGAYSCIGGRSNVDILREAAKGAAAIICVGTCS
SYGGIPHANPNPTGAVAVSDVIKDKPIVNIPGCPPIPVVMTGVLAHYIAFGSLPELDAKNRPKAFFGETIHDRCYRRPFY
DQGKFAKTFDDEGARKGWCLFELGCKGPVTHNACATVKWNGGTSWPVESGHGCLGCSEPDFWDAGSFYKALSQPSGPLNV
GLAATAGGLATGAAVTVANRAKKSAARASHRTITVEDLEK

Specific function: This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions [H]

COG id: COG1740

COG function: function code C; Ni,Fe-hydrogenase I small subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family [H]

Homologues:

Organism=Escherichia coli, GI1787206, Length=299, Percent_Identity=49.1638795986622, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI1789371, Length=306, Percent_Identity=48.0392156862745, Blast_Score=289, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR001821
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.12.99.6 [H]

Molecular weight: Translated: 37958; Mature: 37958

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSPLIDMLGRQGVTRRGFLKYCATLASLMALPPAAGRAMAEAIGAVRRPSVIWLPFQE
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEHHH
CTGCTESITRSHSPTIEGLIFEAISLDYQETLMAAAGHRAEAARDAAIRDNFGKYLLVVD
HCCCHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEC
GSVPLGAEGAYSCIGGRSNVDILREAAKGAAAIICVGTCSSYGGIPHANPNPTGAVAVSD
CCCCCCCCCCHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
VIKDKPIVNIPGCPPIPVVMTGVLAHYIAFGSLPELDAKNRPKAFFGETIHDRCYRRPFY
HHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
DQGKFAKTFDDEGARKGWCLFELGCKGPVTHNACATVKWNGGTSWPVESGHGCLGCSEPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
FWDAGSFYKALSQPSGPLNVGLAATAGGLATGAAVTVANRAKKSAARASHRTITVEDLEK
CCCCHHHHHHHCCCCCCCEECEECCCCCHHCCHHHHHHHHHHHHHHHHHCCEEECCCCCC
>Mature Secondary Structure
MQQSPLIDMLGRQGVTRRGFLKYCATLASLMALPPAAGRAMAEAIGAVRRPSVIWLPFQE
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEHHH
CTGCTESITRSHSPTIEGLIFEAISLDYQETLMAAAGHRAEAARDAAIRDNFGKYLLVVD
HCCCHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEC
GSVPLGAEGAYSCIGGRSNVDILREAAKGAAAIICVGTCSSYGGIPHANPNPTGAVAVSD
CCCCCCCCCCHHHCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
VIKDKPIVNIPGCPPIPVVMTGVLAHYIAFGSLPELDAKNRPKAFFGETIHDRCYRRPFY
HHCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
DQGKFAKTFDDEGARKGWCLFELGCKGPVTHNACATVKWNGGTSWPVESGHGCLGCSEPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
FWDAGSFYKALSQPSGPLNVGLAATAGGLATGAAVTVANRAKKSAARASHRTITVEDLEK
CCCCHHHHHHHCCCCCCCEECEECCCCCHHCCHHHHHHHHHHHHHHHHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2265761 [H]