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The map label for this gene is 74317394

Identifier: 74317394

GI number: 74317394

Start: 1456757

End: 1458019

Strand: Reverse

Name: 74317394

Synonym: Tbd_1376

Alternate gene names: NA

Gene position: 1458019-1456757 (Counterclockwise)

Preceding gene: 74317395

Following gene: 74317393

Centisome position: 50.11

GC content: 63.66

Gene sequence:

>1263_bases
ATGAGTGCGTCACTCGAAAAAGGCATCCATGCCCTCAAGGAAGTCATCGATGCCCCCATCGCCAGCTATTTCGAGAGCTG
CGTGCACTGCGGCATCTGCGCCGACGCCTGCCTCTTCTACACCGAAACGAAGGAACCGAAGTACACGCCGATCAACAAGG
TCGAACCGATGCGGCGCGTGTACGAGCAGGAATACACGCTGCTCGGCCGGCTGAAGAAACTGGTCGGCCTTTCCAAACCG
GTCACCGACGCCGAGCTCGACGCCTGGCAGCACCTCGCCTACGACGCCTGCACGCTGTGCGATCGTTGCTCGCTGGTCTG
CCCGGTCGGCAACGACATCACCTACATGATCCGCAAGTTTCGCGAAGGCCTCGCCGTCTCCGGTCACGCGCCGGACGGCA
TCCGCAGCGCGACCAAGCGCACGGTCGAAGTGGGGGGGCCGATGGGCCTCAAGTGGCCGGCGGTCGCCAACGTCCTGCGC
AAGGTCGAGGAGAAGACCGGGGTGCCGATTCCGGTCGACCGCGCAGGCGTCGACTACATGATCCTGCTGTCGTCGATGGA
AGTCGTGAACTACCCCGAGTACATCGAGGCCCTCGTGAAGATCATGCATCGCGCGGGCCTGAGCTTCACGATCGCGTCCG
ATGCCTACGAGGCGACCAACGCCGGGATCCAGATCGGCAACTCCGATCTCGCCGAGGTCATCGTCGCGCGCATCGTGCTG
GCCGCCGAACGGCTCAAGGTGAGGAACGTGCTGTCGCCCGAATGCGGTCATGCCTACATGGCGATCCGCTGGGAAGGCCC
CAACCTGATGGGCCGCCCTTACGCCTTCGACGTCGTCCACGTGATCGAATTGCTCGACGCGCTGCGCCAGAAGGGCGTGC
TCAGGATCAAGGACAAGTTCAAGGATCGGTGCATCCTTCATGACCCCTGCCAGGTCGTGCGCCGGGGCGGCGTGCTCAAT
GCGCCCGAGCCGCTGGTGGAGCACGTCGCGGAGAATTACATTCCCATTGTCGACAAGCAGAAGTGGAACTGGTGCTGCGG
CGGCGGCGGAGGCGCTTCGGCGATCCATACGCCGGACGCGGAGGCTTTGCGAGCGCGGGCCTTCGGCGTCAAGAAGCGGC
AGCTCGAGGACGCGGGCGTCGACACGATCGTCACTTTCTGCGCCAATTGCCGCATCACGATGGAAGAGGCAGTCGACCAT
TACGGCATGAATACCAGGCTGCTCGGCTTGACCGAGCTCATGGCGGAGCATCTGGAGGACTGA

Upstream 100 bases:

>100_bases
GCCCACGCCCATCGCGGCGTGCCGGTATGAAACGCGGAGGGCTGCGGCCACGGCGAACGAAGACCGGCCACGCATGCACG
GGCTCAAGGAGAGTGCCACG

Downstream 100 bases:

>100_bases
GTTCATGGCAACAACACAGCGCGTCGTCGTCGATCCCATCACGCGCATCGAGGGCCATCTGCGCATCGAGGCCGAGACCG
ACGTCGACGGCAGGATCCTC

Product: heterodisulfide reductase

Products: NA

Alternate protein names: HMC operon ORF 6 [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSASLEKGIHALKEVIDAPIASYFESCVHCGICADACLFYTETKEPKYTPINKVEPMRRVYEQEYTLLGRLKKLVGLSKP
VTDAELDAWQHLAYDACTLCDRCSLVCPVGNDITYMIRKFREGLAVSGHAPDGIRSATKRTVEVGGPMGLKWPAVANVLR
KVEEKTGVPIPVDRAGVDYMILLSSMEVVNYPEYIEALVKIMHRAGLSFTIASDAYEATNAGIQIGNSDLAEVIVARIVL
AAERLKVRNVLSPECGHAYMAIRWEGPNLMGRPYAFDVVHVIELLDALRQKGVLRIKDKFKDRCILHDPCQVVRRGGVLN
APEPLVEHVAENYIPIVDKQKWNWCCGGGGGASAIHTPDAEALRARAFGVKKRQLEDAGVDTIVTFCANCRITMEEAVDH
YGMNTRLLGLTELMAEHLED

Sequences:

>Translated_420_residues
MSASLEKGIHALKEVIDAPIASYFESCVHCGICADACLFYTETKEPKYTPINKVEPMRRVYEQEYTLLGRLKKLVGLSKP
VTDAELDAWQHLAYDACTLCDRCSLVCPVGNDITYMIRKFREGLAVSGHAPDGIRSATKRTVEVGGPMGLKWPAVANVLR
KVEEKTGVPIPVDRAGVDYMILLSSMEVVNYPEYIEALVKIMHRAGLSFTIASDAYEATNAGIQIGNSDLAEVIVARIVL
AAERLKVRNVLSPECGHAYMAIRWEGPNLMGRPYAFDVVHVIELLDALRQKGVLRIKDKFKDRCILHDPCQVVRRGGVLN
APEPLVEHVAENYIPIVDKQKWNWCCGGGGGASAIHTPDAEALRARAFGVKKRQLEDAGVDTIVTFCANCRITMEEAVDH
YGMNTRLLGLTELMAEHLED
>Mature_419_residues
SASLEKGIHALKEVIDAPIASYFESCVHCGICADACLFYTETKEPKYTPINKVEPMRRVYEQEYTLLGRLKKLVGLSKPV
TDAELDAWQHLAYDACTLCDRCSLVCPVGNDITYMIRKFREGLAVSGHAPDGIRSATKRTVEVGGPMGLKWPAVANVLRK
VEEKTGVPIPVDRAGVDYMILLSSMEVVNYPEYIEALVKIMHRAGLSFTIASDAYEATNAGIQIGNSDLAEVIVARIVLA
AERLKVRNVLSPECGHAYMAIRWEGPNLMGRPYAFDVVHVIELLDALRQKGVLRIKDKFKDRCILHDPCQVVRRGGVLNA
PEPLVEHVAENYIPIVDKQKWNWCCGGGGGASAIHTPDAEALRARAFGVKKRQLEDAGVDTIVTFCANCRITMEEAVDHY
GMNTRLLGLTELMAEHLED

Specific function: HMWC (high-molecular-weight cytochrome c precursor), ORF2, ORF3, ORF4, ORF5, ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfa

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 46440; Mature: 46309

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASLEKGIHALKEVIDAPIASYFESCVHCGICADACLFYTETKEPKYTPINKVEPMRRV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
YEQEYTLLGRLKKLVGLSKPVTDAELDAWQHLAYDACTLCDRCSLVCPVGNDITYMIRKF
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHH
REGLAVSGHAPDGIRSATKRTVEVGGPMGLKWPAVANVLRKVEEKTGVPIPVDRAGVDYM
HHCCEECCCCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ILLSSMEVVNYPEYIEALVKIMHRAGLSFTIASDAYEATNAGIQIGNSDLAEVIVARIVL
HHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCEEECCHHHHHHHHHHHHH
AAERLKVRNVLSPECGHAYMAIRWEGPNLMGRPYAFDVVHVIELLDALRQKGVLRIKDKF
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEHHHH
KDRCILHDPCQVVRRGGVLNAPEPLVEHVAENYIPIVDKQKWNWCCGGGGGASAIHTPDA
CCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCH
EALRARAFGVKKRQLEDAGVDTIVTFCANCRITMEEAVDHYGMNTRLLGLTELMAEHLED
HHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SASLEKGIHALKEVIDAPIASYFESCVHCGICADACLFYTETKEPKYTPINKVEPMRRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
YEQEYTLLGRLKKLVGLSKPVTDAELDAWQHLAYDACTLCDRCSLVCPVGNDITYMIRKF
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHH
REGLAVSGHAPDGIRSATKRTVEVGGPMGLKWPAVANVLRKVEEKTGVPIPVDRAGVDYM
HHCCEECCCCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ILLSSMEVVNYPEYIEALVKIMHRAGLSFTIASDAYEATNAGIQIGNSDLAEVIVARIVL
HHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCEEECCHHHHHHHHHHHHH
AAERLKVRNVLSPECGHAYMAIRWEGPNLMGRPYAFDVVHVIELLDALRQKGVLRIKDKF
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEHHHH
KDRCILHDPCQVVRRGGVLNAPEPLVEHVAENYIPIVDKQKWNWCCGGGGGASAIHTPDA
CCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCH
EALRARAFGVKKRQLEDAGVDTIVTFCANCRITMEEAVDHYGMNTRLLGLTELMAEHLED
HHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]