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The map label for this gene is cusB [H]

Identifier: 74317352

GI number: 74317352

Start: 1417804

End: 1419297

Strand: Reverse

Name: cusB [H]

Synonym: Tbd_1334

Alternate gene names: 74317352

Gene position: 1419297-1417804 (Counterclockwise)

Preceding gene: 74317353

Following gene: 74317351

Centisome position: 48.78

GC content: 69.54

Gene sequence:

>1494_bases
ATGAATCGCCAAACGATTAAAAAAACCGTGCTGGGCCTCTTCGTCGTGGTTGCACTGCTCGCCGCCGGCGTGGCGGCCGG
CCTCTGGTGGGCCGGCCGCTACCCCACGGATACGCAGGATACCCACACCGCGGCCCCCGCGCAGCATGGTCGCACCGTGC
TGTACTGGTACGACCCGATGGTGCCGCAGCAAAAATTCGACAAGCCCGGCAAGTCGCCTTTCATGGACATGGATCTGGTG
CCCAAATACGCCGACGAAGGCGGCGATGCCGCAACCGTCAAAATCGACCCCTGGGTGGCGCAGAACCTGGGCGTGCGTCT
GGCCACCGTCACCCACGCACCCTTCGGCAGCGACGTGACGGCGACCGGCGTCGTCGGCTTCGACGAGCGCGAGGTGGCGA
TCGTGCAGGCGCGCAGCGGCGGCTTCGTGGAACGCGTGGCTAGGCTGGCGCCGAACGATGTCGTTCGATCGGGCGCCTTG
ATCGCGGAACTGCTGGTGCCGGAGTGGGCGGCGGTGCAGCAGGAGTACCTGGCGCTCAAGGCGCTGGGCGACCCCTCACT
GGAAGGCGCCGCGCGCGAGCGCATGCGCTTGAGCGGCATGCCGGAAAGCCTGATTCGCGACGTCGCCGCCCGCGGCAAGA
TCAGGAATCGCATTGCGATCACCGCGCCGCGGGGCGGCGTGATCCAGGAACTCGACGTGCGCGCCGGCATGACCGTGATG
GGCGGCCAGACTTTGGCGCGCATCAACGGCATCGGCACCGTCTGGCTCGACGTCGCGGTGCCGGAAGCCCGCGCCGGCTC
GGTGCGGATCGGGCAGGCGGCCGAGGCCCATTTCGCTGCGTTTCCGGGCGAACCGGTGCAGGGCCGCGTCACCGCGCTGC
TGCCGGCGCTGGACGATACCGCCCGCACGCTGAGGGTCCGAGTCGAACTGCCCAATCCCGGCGGGCGCCTGCGGCCGGGA
TTGACCGCGCAGGTCAGCCTCAGGGGGGCGGGCGGCGACTCGGCGCTGCGCGTGCCAACCGAAGCGGTGATCCGCACCGG
ACGCCGCGCGCTCGTCGTCGTGGCGGAGGCTGAGGGGCGCTACCGGCCGGTCGAAGTCACATTGGGCGCCGAGTCGGGCA
GCGACACCGTCATCCTGTCCGGCCTCGCCGAGGGCCAGAAAGTCGTCGCCAGCGGCCAGTTCCTGATTGACTCCGAAGCC
AGCCTGCAGGGCATCGTCGCGCGCGGGACAGGCGAAGCGGCCGCCGCGCCGGCCGCGCTGCACGAGGCTGATGGCGTAAT
CGACGACATTTCCGCCGAATATGTGACGCTCACCCACGGCCCCTTCAAGACCCTGGCGATGCCCGGCATGACCATGGAGT
TTCCGCTGGCCCGCCCTGAACTCGCCAAGGGCCTGAAGGCGGGCGACCGGGTGAGGGTCGGCGCGCGCGAGACCGCCGAC
GGGCTGGTAGTCGAAAAACTCGTCAAGACCGACAAGACGGGGGGCGCCAAATGA

Upstream 100 bases:

>100_bases
ACGCCGAACTCATGGCCATCGCGCTCGAAGGCGAGCGCCGACAGTTGGCCGCCCGCCTGCTCTATGCCTACAGCGAACCC
GATTTGACCGGAGAAAAACA

Downstream 100 bases:

>100_bases
TTGCGCGCCTGATTCGCTGGTCGGTCGCCAACCGTTTCCTGGTCCTGCTGGCGACGCTGTTCACCGTGGCCTGGGGCATC
TGGGCGGTTAAGACCACGCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNRQTIKKTVLGLFVVVALLAAGVAAGLWWAGRYPTDTQDTHTAAPAQHGRTVLYWYDPMVPQQKFDKPGKSPFMDMDLV
PKYADEGGDAATVKIDPWVAQNLGVRLATVTHAPFGSDVTATGVVGFDEREVAIVQARSGGFVERVARLAPNDVVRSGAL
IAELLVPEWAAVQQEYLALKALGDPSLEGAARERMRLSGMPESLIRDVAARGKIRNRIAITAPRGGVIQELDVRAGMTVM
GGQTLARINGIGTVWLDVAVPEARAGSVRIGQAAEAHFAAFPGEPVQGRVTALLPALDDTARTLRVRVELPNPGGRLRPG
LTAQVSLRGAGGDSALRVPTEAVIRTGRRALVVVAEAEGRYRPVEVTLGAESGSDTVILSGLAEGQKVVASGQFLIDSEA
SLQGIVARGTGEAAAAPAALHEADGVIDDISAEYVTLTHGPFKTLAMPGMTMEFPLARPELAKGLKAGDRVRVGARETAD
GLVVEKLVKTDKTGGAK

Sequences:

>Translated_497_residues
MNRQTIKKTVLGLFVVVALLAAGVAAGLWWAGRYPTDTQDTHTAAPAQHGRTVLYWYDPMVPQQKFDKPGKSPFMDMDLV
PKYADEGGDAATVKIDPWVAQNLGVRLATVTHAPFGSDVTATGVVGFDEREVAIVQARSGGFVERVARLAPNDVVRSGAL
IAELLVPEWAAVQQEYLALKALGDPSLEGAARERMRLSGMPESLIRDVAARGKIRNRIAITAPRGGVIQELDVRAGMTVM
GGQTLARINGIGTVWLDVAVPEARAGSVRIGQAAEAHFAAFPGEPVQGRVTALLPALDDTARTLRVRVELPNPGGRLRPG
LTAQVSLRGAGGDSALRVPTEAVIRTGRRALVVVAEAEGRYRPVEVTLGAESGSDTVILSGLAEGQKVVASGQFLIDSEA
SLQGIVARGTGEAAAAPAALHEADGVIDDISAEYVTLTHGPFKTLAMPGMTMEFPLARPELAKGLKAGDRVRVGARETAD
GLVVEKLVKTDKTGGAK
>Mature_497_residues
MNRQTIKKTVLGLFVVVALLAAGVAAGLWWAGRYPTDTQDTHTAAPAQHGRTVLYWYDPMVPQQKFDKPGKSPFMDMDLV
PKYADEGGDAATVKIDPWVAQNLGVRLATVTHAPFGSDVTATGVVGFDEREVAIVQARSGGFVERVARLAPNDVVRSGAL
IAELLVPEWAAVQQEYLALKALGDPSLEGAARERMRLSGMPESLIRDVAARGKIRNRIAITAPRGGVIQELDVRAGMTVM
GGQTLARINGIGTVWLDVAVPEARAGSVRIGQAAEAHFAAFPGEPVQGRVTALLPALDDTARTLRVRVELPNPGGRLRPG
LTAQVSLRGAGGDSALRVPTEAVIRTGRRALVVVAEAEGRYRPVEVTLGAESGSDTVILSGLAEGQKVVASGQFLIDSEA
SLQGIVARGTGEAAAAPAALHEADGVIDDISAEYVTLTHGPFKTLAMPGMTMEFPLARPELAKGLKAGDRVRVGARETAD
GLVVEKLVKTDKTGGAK

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=404, Percent_Identity=41.0891089108911, Blast_Score=298, Evalue=6e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52321; Mature: 52321

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRQTIKKTVLGLFVVVALLAAGVAAGLWWAGRYPTDTQDTHTAAPAQHGRTVLYWYDPM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCEEEEEECCC
VPQQKFDKPGKSPFMDMDLVPKYADEGGDAATVKIDPWVAQNLGVRLATVTHAPFGSDVT
CCHHHCCCCCCCCCCCCCCCCHHHCCCCCEEEEEECCHHHCCCCEEEEEEEECCCCCCCE
ATGVVGFDEREVAIVQARSGGFVERVARLAPNDVVRSGALIAELLVPEWAAVQQEYLALK
EEEEECCCCCEEEEEEECCCCHHHHHHHHCCHHHHHCCHHHHHHHCCCHHHHHHHHHHHH
ALGDPSLEGAARERMRLSGMPESLIRDVAARGKIRNRIAITAPRGGVIQELDVRAGMTVM
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHCCCEEE
GGQTLARINGIGTVWLDVAVPEARAGSVRIGQAAEAHFAAFPGEPVQGRVTALLPALDDT
CCCEEEEECCCEEEEEEEECCCCCCCCEEECCCCCCCEEECCCCCCCCEEEEEECCCCCC
ARTLRVRVELPNPGGRLRPGLTAQVSLRGAGGDSALRVPTEAVIRTGRRALVVVAEAEGR
CEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCEEECCHHHHHHCCCEEEEEEEECCCC
YRPVEVTLGAESGSDTVILSGLAEGQKVVASGQFLIDSEASLQGIVARGTGEAAAAPAAL
EEEEEEEEECCCCCCEEEEEECCCCCEEEECCCEEEECCCCCEEEEEECCCCHHHCCHHH
HEADGVIDDISAEYVTLTHGPFKTLAMPGMTMEFPLARPELAKGLKAGDRVRVGARETAD
HHHCCCCCCCCCCEEEEECCCCHHHCCCCCEEECCCCCHHHHHCCCCCCEEEECCCCCCC
GLVVEKLVKTDKTGGAK
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNRQTIKKTVLGLFVVVALLAAGVAAGLWWAGRYPTDTQDTHTAAPAQHGRTVLYWYDPM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCEEEEEECCC
VPQQKFDKPGKSPFMDMDLVPKYADEGGDAATVKIDPWVAQNLGVRLATVTHAPFGSDVT
CCHHHCCCCCCCCCCCCCCCCHHHCCCCCEEEEEECCHHHCCCCEEEEEEEECCCCCCCE
ATGVVGFDEREVAIVQARSGGFVERVARLAPNDVVRSGALIAELLVPEWAAVQQEYLALK
EEEEECCCCCEEEEEEECCCCHHHHHHHHCCHHHHHCCHHHHHHHCCCHHHHHHHHHHHH
ALGDPSLEGAARERMRLSGMPESLIRDVAARGKIRNRIAITAPRGGVIQELDVRAGMTVM
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHCCCEEE
GGQTLARINGIGTVWLDVAVPEARAGSVRIGQAAEAHFAAFPGEPVQGRVTALLPALDDT
CCCEEEEECCCEEEEEEEECCCCCCCCEEECCCCCCCEEECCCCCCCCEEEEEECCCCCC
ARTLRVRVELPNPGGRLRPGLTAQVSLRGAGGDSALRVPTEAVIRTGRRALVVVAEAEGR
CEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCEEECCHHHHHHCCCEEEEEEEECCCC
YRPVEVTLGAESGSDTVILSGLAEGQKVVASGQFLIDSEASLQGIVARGTGEAAAAPAAL
EEEEEEEEECCCCCCEEEEEECCCCCEEEECCCEEEECCCCCEEEEEECCCCHHHCCHHH
HEADGVIDDISAEYVTLTHGPFKTLAMPGMTMEFPLARPELAKGLKAGDRVRVGARETAD
HHHCCCCCCCCCCEEEEECCCCHHHCCCCCEEECCCCCHHHHHCCCCCCEEEECCCCCCC
GLVVEKLVKTDKTGGAK
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]