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The map label for this gene is pilQ [H]

Identifier: 74317318

GI number: 74317318

Start: 1371056

End: 1373059

Strand: Direct

Name: pilQ [H]

Synonym: Tbd_1300

Alternate gene names: 74317318

Gene position: 1371056-1373059 (Clockwise)

Preceding gene: 74317317

Following gene: 74317319

Centisome position: 47.12

GC content: 68.11

Gene sequence:

>2004_bases
TTGAAAACGAAGCACGTCGTTGTGAGTCTTGTCTGTGTTCTGGGCCTTTCGGGCTGCGCTGCCGACCGCGCCTTCACCCG
CGGCAAGGGCATGCTGGAGCAGGGCCAGACCGAAGCCGGTCTGCGCGAGGTCGAAAAGGCCGCGCGCATCGCCCCCGAGA
ACAAGGAATACCGGATCTACCTCGCGCGCCAGCGCGAGGGCTCGATCAACACGCTGCTCGGTGAGGCCGAGCAGGCGCGG
CGGACCGGGCGCCTCGACGCCGCCGAGCAGGCCTTCCGTCGCGCCCTCGCGCTCGATGCGGAAAACCGTCGGGCGGCGGA
CGGCCTCGAGGCCGTGGCGACCGCGCGGAAGCATCGCGTGCTGCTCGCCGAAGCCGAGACGCTGGCCGTGCAGGGCAATC
TCGCAGCCGCGGCGACGAAGCTCGACACCGTGCTCGCCGAGGACCCGCGCAGTGCCGAGGGCCGCGCGCTGAAGACGCGA
CTCGCCGCGCTGAAGGCCGAGAAGCGGTCGGAACTGCCGGGCTTGCGCTCGCTCTTCGAGAAGCCGATCACGCTCGAATT
CCGCAACGCCGACCTCAAGGCGATCTTCGAAGTCATCTCGCGCAGCGCCGGGATCAATTTCATTTTCGACAAGGACGTCC
GCCAGGACCTCGTCGCGAGCATCTTCGTCAGGAACACGCGCATCGAGAGCGCGATCGACTTCCTGCTCATGAGCAACCAG
CTCGCGAAGAAGGTGCTCAACGAGAACACGGTTCTGGTCTACCCGAACATCCCGGCGAAGACCCGCGACTACCAGGATCT
TCGGGCCAAGACCTTCTATCTCGCGAGCATGGACGCCAAGCAGGCGCTCAACATCGTCAAGACCATCGTCAAGACCCGCG
ACGTCGTCATCGACGAGAAGCTCAACACGCTCGTGATGCGCGATACCCCCGACGCGATCCGGCTCGCCGAAAAACTGCTC
GGAAGCCAGGACCTCGCGGAATCCGAGGTGCTGCTCGAGGTCGAAGTGCTCGAGGTCAGCCGCAGCCGCCTGAGCGACAT
CGGCATCACGCCGCCGACCGAGGCGACGTTCCGCACGCTCGGTCCTTCGGGCGCGCCGAGCACGACGCTCGCCGATCTCA
AAGGGCTCAACTCCGGGCTGATCGGGGTGTCGTCGCTGAGCGCGAGCGTGCGCGCGCGCATGGACAACGGCGATACCAAC
CTGCTCGCGAACCCGCGCATCCGCGTCAAGAACCGCGAGAAGGCCAAGGTGCACATCGGCGAGCGCGTGCCGATCATCAC
GACCACGGTGACCTCGGCCGGCACGACGAGCTTTTTGCCCGAGACGGTCAACTATCTCGACGTCGGCATCAAGTTCGAGG
TCGAGCCGCTCATTTCGCTGAACGACGAGGTGACGATCAAGGTCGCGCTCGAGGTGAGCAGCCTCGGACAGAAGAGCGTG
ACCAAGAGCGGCAGCGAGGTCTACCGGGTCGGCACGCGCAACGCGTCGACGACGCTCGCGCTGCGCGATGGCGAAACGCA
GGCGCTGGCTGGTCTCATCAGCGACGAGGAGCGCGAGACGGTCAACGGGATTCCCGGCTTCGGCCGCATCCCGGCGATCG
GCCGGCTGTTCGCGAGCAAGAGCAACAGCACCGACAAGACGGAGATCGTCCTCCTCATCACGCCGCACATCGTGCGCAAT
CTCGACCGCACGGCGCTCACCGCGTCCGACTTCGCGGCCGGCACCGATTCGGCAGCCGGCAGCGCGCCGGTGACGCTGCA
GGCGATCACGCCCGAAGTCATGCGCGCGGTCGAGGAAGGCACGGCAGGCGCGCCGGGCGCGGCGCCCGCGGCGCCGGCGG
ACGCACCCGCAGGCGGCCAGGCGCCAGCCGGGGTGGAGATCGGACGCGAACCGGCGGCCGAGGGCGGCGACGCCGCGGGC
GAACCGGCCGCAGCGCAGGACGCCGAACCGGGGAACGCAGCGCCCGAGCCCTCCGCCGACGGCGACGCACAGGAAGGGTC
CTAG

Upstream 100 bases:

>100_bases
TCGATTCGACCTACCGGATCGACAGTGTCGACGCACGCAGCATGGCGCTGACCTACCTCCCCCTGGACATGAAGCAAACC
CTCTCCCTCGGAGAAAGAAA

Downstream 100 bases:

>100_bases
CATGGGCGCCTCCCGCCAGCAGCCGGCGCGGGCCCGCCGCCGCGGGGCCGGCTTCACGCTGATCGAACTGGTCGTCACCG
TCGCGATCGTCGGCATCCTC

Product: type II secretion system protein D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MKTKHVVVSLVCVLGLSGCAADRAFTRGKGMLEQGQTEAGLREVEKAARIAPENKEYRIYLARQREGSINTLLGEAEQAR
RTGRLDAAEQAFRRALALDAENRRAADGLEAVATARKHRVLLAEAETLAVQGNLAAAATKLDTVLAEDPRSAEGRALKTR
LAALKAEKRSELPGLRSLFEKPITLEFRNADLKAIFEVISRSAGINFIFDKDVRQDLVASIFVRNTRIESAIDFLLMSNQ
LAKKVLNENTVLVYPNIPAKTRDYQDLRAKTFYLASMDAKQALNIVKTIVKTRDVVIDEKLNTLVMRDTPDAIRLAEKLL
GSQDLAESEVLLEVEVLEVSRSRLSDIGITPPTEATFRTLGPSGAPSTTLADLKGLNSGLIGVSSLSASVRARMDNGDTN
LLANPRIRVKNREKAKVHIGERVPIITTTVTSAGTTSFLPETVNYLDVGIKFEVEPLISLNDEVTIKVALEVSSLGQKSV
TKSGSEVYRVGTRNASTTLALRDGETQALAGLISDEERETVNGIPGFGRIPAIGRLFASKSNSTDKTEIVLLITPHIVRN
LDRTALTASDFAAGTDSAAGSAPVTLQAITPEVMRAVEEGTAGAPGAAPAAPADAPAGGQAPAGVEIGREPAAEGGDAAG
EPAAAQDAEPGNAAPEPSADGDAQEGS

Sequences:

>Translated_667_residues
MKTKHVVVSLVCVLGLSGCAADRAFTRGKGMLEQGQTEAGLREVEKAARIAPENKEYRIYLARQREGSINTLLGEAEQAR
RTGRLDAAEQAFRRALALDAENRRAADGLEAVATARKHRVLLAEAETLAVQGNLAAAATKLDTVLAEDPRSAEGRALKTR
LAALKAEKRSELPGLRSLFEKPITLEFRNADLKAIFEVISRSAGINFIFDKDVRQDLVASIFVRNTRIESAIDFLLMSNQ
LAKKVLNENTVLVYPNIPAKTRDYQDLRAKTFYLASMDAKQALNIVKTIVKTRDVVIDEKLNTLVMRDTPDAIRLAEKLL
GSQDLAESEVLLEVEVLEVSRSRLSDIGITPPTEATFRTLGPSGAPSTTLADLKGLNSGLIGVSSLSASVRARMDNGDTN
LLANPRIRVKNREKAKVHIGERVPIITTTVTSAGTTSFLPETVNYLDVGIKFEVEPLISLNDEVTIKVALEVSSLGQKSV
TKSGSEVYRVGTRNASTTLALRDGETQALAGLISDEERETVNGIPGFGRIPAIGRLFASKSNSTDKTEIVLLITPHIVRN
LDRTALTASDFAAGTDSAAGSAPVTLQAITPEVMRAVEEGTAGAPGAAPAAPADAPAGGQAPAGVEIGREPAAEGGDAAG
EPAAAQDAEPGNAAPEPSADGDAQEGS
>Mature_667_residues
MKTKHVVVSLVCVLGLSGCAADRAFTRGKGMLEQGQTEAGLREVEKAARIAPENKEYRIYLARQREGSINTLLGEAEQAR
RTGRLDAAEQAFRRALALDAENRRAADGLEAVATARKHRVLLAEAETLAVQGNLAAAATKLDTVLAEDPRSAEGRALKTR
LAALKAEKRSELPGLRSLFEKPITLEFRNADLKAIFEVISRSAGINFIFDKDVRQDLVASIFVRNTRIESAIDFLLMSNQ
LAKKVLNENTVLVYPNIPAKTRDYQDLRAKTFYLASMDAKQALNIVKTIVKTRDVVIDEKLNTLVMRDTPDAIRLAEKLL
GSQDLAESEVLLEVEVLEVSRSRLSDIGITPPTEATFRTLGPSGAPSTTLADLKGLNSGLIGVSSLSASVRARMDNGDTN
LLANPRIRVKNREKAKVHIGERVPIITTTVTSAGTTSFLPETVNYLDVGIKFEVEPLISLNDEVTIKVALEVSSLGQKSV
TKSGSEVYRVGTRNASTTLALRDGETQALAGLISDEERETVNGIPGFGRIPAIGRLFASKSNSTDKTEIVLLITPHIVRN
LDRTALTASDFAAGTDSAAGSAPVTLQAITPEVMRAVEEGTAGAPGAAPAAPADAPAGGQAPAGVEIGREPAAEGGDAAG
EPAAAQDAEPGNAAPEPSADGDAQEGS

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=407, Percent_Identity=20.3931203931204, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87082242, Length=291, Percent_Identity=28.1786941580756, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 70846; Mature: 70846

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKHVVVSLVCVLGLSGCAADRAFTRGKGMLEQGQTEAGLREVEKAARIAPENKEYRIY
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCEEEE
LARQREGSINTLLGEAEQARRTGRLDAAEQAFRRALALDAENRRAADGLEAVATARKHRV
EEECCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEE
LLAEAETLAVQGNLAAAATKLDTVLAEDPRSAEGRALKTRLAALKAEKRSELPGLRSLFE
EEEECCEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHC
KPITLEFRNADLKAIFEVISRSAGINFIFDKDVRQDLVASIFVRNTRIESAIDFLLMSNQ
CCCEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKKVLNENTVLVYPNIPAKTRDYQDLRAKTFYLASMDAKQALNIVKTIVKTRDVVIDEK
HHHHHHCCCCEEEECCCCCCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHEEECC
LNTLVMRDTPDAIRLAEKLLGSQDLAESEVLLEVEVLEVSRSRLSDIGITPPTEATFRTL
CCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHCC
GPSGAPSTTLADLKGLNSGLIGVSSLSASVRARMDNGDTNLLANPRIRVKNREKAKVHIG
CCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHEECCCCCCCEEECCEEEECCCCCCEEEEC
ERVPIITTTVTSAGTTSFLPETVNYLDVGIKFEVEPLISLNDEVTIKVALEVSSLGQKSV
CCCCEEEEEECCCCCCHHCHHHHHHEEECEEEEECCCCCCCCCEEEEEEEEHHHCCCHHH
TKSGSEVYRVGTRNASTTLALRDGETQALAGLISDEERETVNGIPGFGRIPAIGRLFASK
HCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHCC
SNSTDKTEIVLLITPHIVRNLDRTALTASDFAAGTDSAAGSAPVTLQAITPEVMRAVEEG
CCCCCCEEEEEEECCHHHHCCCHHHEEHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHC
TAGAPGAAPAAPADAPAGGQAPAGVEIGREPAAEGGDAAGEPAAAQDAEPGNAAPEPSAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDAQEGS
CCCCCCC
>Mature Secondary Structure
MKTKHVVVSLVCVLGLSGCAADRAFTRGKGMLEQGQTEAGLREVEKAARIAPENKEYRIY
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCEEEE
LARQREGSINTLLGEAEQARRTGRLDAAEQAFRRALALDAENRRAADGLEAVATARKHRV
EEECCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEE
LLAEAETLAVQGNLAAAATKLDTVLAEDPRSAEGRALKTRLAALKAEKRSELPGLRSLFE
EEEECCEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHC
KPITLEFRNADLKAIFEVISRSAGINFIFDKDVRQDLVASIFVRNTRIESAIDFLLMSNQ
CCCEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKKVLNENTVLVYPNIPAKTRDYQDLRAKTFYLASMDAKQALNIVKTIVKTRDVVIDEK
HHHHHHCCCCEEEECCCCCCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHEEECC
LNTLVMRDTPDAIRLAEKLLGSQDLAESEVLLEVEVLEVSRSRLSDIGITPPTEATFRTL
CCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHCC
GPSGAPSTTLADLKGLNSGLIGVSSLSASVRARMDNGDTNLLANPRIRVKNREKAKVHIG
CCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHEECCCCCCCEEECCEEEECCCCCCEEEEC
ERVPIITTTVTSAGTTSFLPETVNYLDVGIKFEVEPLISLNDEVTIKVALEVSSLGQKSV
CCCCEEEEEECCCCCCHHCHHHHHHEEECEEEEECCCCCCCCCEEEEEEEEHHHCCCHHH
TKSGSEVYRVGTRNASTTLALRDGETQALAGLISDEERETVNGIPGFGRIPAIGRLFASK
HCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHCC
SNSTDKTEIVLLITPHIVRNLDRTALTASDFAAGTDSAAGSAPVTLQAITPEVMRAVEEG
CCCCCCEEEEEEECCHHHHCCCHHHEEHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHC
TAGAPGAAPAAPADAPAGGQAPAGVEIGREPAAEGGDAAGEPAAAQDAEPGNAAPEPSAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDAQEGS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]