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The map label for this gene is pilC [H]

Identifier: 74317312

GI number: 74317312

Start: 1365769

End: 1366938

Strand: Direct

Name: pilC [H]

Synonym: Tbd_1294

Alternate gene names: 74317312

Gene position: 1365769-1366938 (Clockwise)

Preceding gene: 74317311

Following gene: 74317313

Centisome position: 46.94

GC content: 68.29

Gene sequence:

>1170_bases
GTGGGAAGCGCGTCGGCGATCGTCTCGCTCGTGCTCGAGGCGCCTGACGCCGCGAGTGCCGAGGCGCGCGCCGCCGCCGA
CGGCCTGACGGTGCTGTCGGTCCGCCGCCGTGCGAGCGGGGACGGCTGGCGCCTCGGCCGCGCGAAGCGCTTCCCGCTCC
AGCTTTTCACGCAGGAACTGCTGGCCCTGCTCAACGCGGGCCTCGCCCTGGTCGAGGCGCTCGAGGCGCTCGCCGAAAAG
GAGGCGCGGCCCGAGAGCAAAAGCGTTTTCGACCAGCTGCTGCGCGCGCTTTACGAAGGGCAAACCCTGTCGGCGGCGCT
CGAGAAGCTGCCGGCGGTTTTTCCCGCGCTCTACGTCGCGAGCATCCGGGCGAGCGAGAAAACCGGCGACCTGCCGGAGA
CGCTGCGCCGCTACATTGCCTACCAGGCCCAGCTCGACGTGATCCGCAAGAAACTCGTCAGCGCGTCGATCTACCCGCTC
GTGCTCATCGGCGTCGGCGGGCTCGTCGCGCTGTTCCTGATGGCCTACGTCGTGCCGCGCTTCAGCGAAGTCTATGAAGG
CCTGGACGGCGACCTGCCGCTGATGTCGCGTCTGCTCATGCAGTGGGGCCAGTTGCTTGAACAGCACGGCAGTGCGGTGC
TGCTCGTGCTGGCGGCGCTGCTGGCGGGCCTCGTCTTCGGTCTCACCCGGCCGGCGCTCAGGGCCTGGGCGGGACAAAAG
CTCTGGCAGATTCCATCGGTCGGCGAGCGCATGCGCGTCTACCAGCTCGCGCGTTTCTACCGCACGCTCGGCATGCTGCT
CGCCGGCGGCGTCTCGATCGTGCCGGCCCTCGACATGGCGTCGGGAATCCTCCATGCCTCGCTGCGTGACGGCCTTGCAC
GGGCCGGCGCGCGCATCCGCGAGGGGCAGCCGATCTCGTTCGCGATGGAAGCCAATGGTCTGACCACCCAGGTCGCGCTG
CGCATGCTGCGCGTCGGCGAGCGCACCGGGCAGATGGGCGAAATGATGGAGCGCATCGCGGCCTTCTACGACGAGGAAAT
GGCGCGCTGGGTCGACTGGTTCACCAAGCTGTTCGAGCCCTTGCTGATGGCCGTGATCGGGGTCGTCATCGGCGCACTCG
TGGTCCTGATGTACATGCCGATCTTCGAACTCGCGGGGAGCATTCAATGA

Upstream 100 bases:

>100_bases
ACCTGTCTTCCTACGGTACCGACGGCCAGCCTGGCGGCACCGGCGAATCCGCCGACATCACGAACTGGTAAGCGCGATGG
CACAGTTCGAGGTCCGTGGG

Downstream 100 bases:

>100_bases
GCATCGCGCAACAGGTTGCGGCCGACACCGCGTTTCCGATCAGTGCCGGGCAGTTCGGCGCGGCGCGTGCCGAGGCGGCG
CGCAGCGGGCGCCCGCTGCT

Product: type II secretion system protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MGSASAIVSLVLEAPDAASAEARAAADGLTVLSVRRRASGDGWRLGRAKRFPLQLFTQELLALLNAGLALVEALEALAEK
EARPESKSVFDQLLRALYEGQTLSAALEKLPAVFPALYVASIRASEKTGDLPETLRRYIAYQAQLDVIRKKLVSASIYPL
VLIGVGGLVALFLMAYVVPRFSEVYEGLDGDLPLMSRLLMQWGQLLEQHGSAVLLVLAALLAGLVFGLTRPALRAWAGQK
LWQIPSVGERMRVYQLARFYRTLGMLLAGGVSIVPALDMASGILHASLRDGLARAGARIREGQPISFAMEANGLTTQVAL
RMLRVGERTGQMGEMMERIAAFYDEEMARWVDWFTKLFEPLLMAVIGVVIGALVVLMYMPIFELAGSIQ

Sequences:

>Translated_389_residues
MGSASAIVSLVLEAPDAASAEARAAADGLTVLSVRRRASGDGWRLGRAKRFPLQLFTQELLALLNAGLALVEALEALAEK
EARPESKSVFDQLLRALYEGQTLSAALEKLPAVFPALYVASIRASEKTGDLPETLRRYIAYQAQLDVIRKKLVSASIYPL
VLIGVGGLVALFLMAYVVPRFSEVYEGLDGDLPLMSRLLMQWGQLLEQHGSAVLLVLAALLAGLVFGLTRPALRAWAGQK
LWQIPSVGERMRVYQLARFYRTLGMLLAGGVSIVPALDMASGILHASLRDGLARAGARIREGQPISFAMEANGLTTQVAL
RMLRVGERTGQMGEMMERIAAFYDEEMARWVDWFTKLFEPLLMAVIGVVIGALVVLMYMPIFELAGSIQ
>Mature_388_residues
GSASAIVSLVLEAPDAASAEARAAADGLTVLSVRRRASGDGWRLGRAKRFPLQLFTQELLALLNAGLALVEALEALAEKE
ARPESKSVFDQLLRALYEGQTLSAALEKLPAVFPALYVASIRASEKTGDLPETLRRYIAYQAQLDVIRKKLVSASIYPLV
LIGVGGLVALFLMAYVVPRFSEVYEGLDGDLPLMSRLLMQWGQLLEQHGSAVLLVLAALLAGLVFGLTRPALRAWAGQKL
WQIPSVGERMRVYQLARFYRTLGMLLAGGVSIVPALDMASGILHASLRDGLARAGARIREGQPISFAMEANGLTTQVALR
MLRVGERTGQMGEMMERIAAFYDEEMARWVDWFTKLFEPLLMAVIGVVIGALVVLMYMPIFELAGSIQ

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=381, Percent_Identity=28.3464566929134, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1786295, Length=369, Percent_Identity=28.7262872628726, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42347; Mature: 42215

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSASAIVSLVLEAPDAASAEARAAADGLTVLSVRRRASGDGWRLGRAKRFPLQLFTQEL
CCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LALLNAGLALVEALEALAEKEARPESKSVFDQLLRALYEGQTLSAALEKLPAVFPALYVA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SIRASEKTGDLPETLRRYIAYQAQLDVIRKKLVSASIYPLVLIGVGGLVALFLMAYVVPR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSEVYEGLDGDLPLMSRLLMQWGQLLEQHGSAVLLVLAALLAGLVFGLTRPALRAWAGQK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LWQIPSVGERMRVYQLARFYRTLGMLLAGGVSIVPALDMASGILHASLRDGLARAGARIR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
EGQPISFAMEANGLTTQVALRMLRVGERTGQMGEMMERIAAFYDEEMARWVDWFTKLFEP
CCCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMAVIGVVIGALVVLMYMPIFELAGSIQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GSASAIVSLVLEAPDAASAEARAAADGLTVLSVRRRASGDGWRLGRAKRFPLQLFTQEL
CCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LALLNAGLALVEALEALAEKEARPESKSVFDQLLRALYEGQTLSAALEKLPAVFPALYVA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SIRASEKTGDLPETLRRYIAYQAQLDVIRKKLVSASIYPLVLIGVGGLVALFLMAYVVPR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSEVYEGLDGDLPLMSRLLMQWGQLLEQHGSAVLLVLAALLAGLVFGLTRPALRAWAGQK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LWQIPSVGERMRVYQLARFYRTLGMLLAGGVSIVPALDMASGILHASLRDGLARAGARIR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
EGQPISFAMEANGLTTQVALRMLRVGERTGQMGEMMERIAAFYDEEMARWVDWFTKLFEP
CCCCCEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMAVIGVVIGALVVLMYMPIFELAGSIQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]