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The map label for this gene is csd [H]

Identifier: 74317298

GI number: 74317298

Start: 1346220

End: 1347455

Strand: Direct

Name: csd [H]

Synonym: Tbd_1280

Alternate gene names: 74317298

Gene position: 1346220-1347455 (Clockwise)

Preceding gene: 74317294

Following gene: 74317301

Centisome position: 46.26

GC content: 70.15

Gene sequence:

>1236_bases
ATGATCCGGACGGTGTTCGCGCTTGGCGCTCACCCGGTCCGCGCCGCCTTTTTGATGGAGGAAAACATGTCCGACCCGCT
CACGGCGACGCCCGCCGCGCCCGCGCATTCCCTCGGCGACGAGTTCGCGCTCGACCCGGGCCTCGTCTATCTCAACCACG
CGGCCGTCGCGCCCTGGCCGCGGCGCACCGCGCGCGCCGTCCAGCGCTTCGCCGACGAGAGCCTGCATTACGGCGCGAGC
CATTTCCCGCGCTGGATGGAGAAGGAAGTGCAGTTGCGCGGTCAGTGCCGCGACCTCGTCAACGCGCCGTCGGCGGACGA
CATCGCGCTTTTGAAGAACACCTCCGAGGCCTTGTCGGTCGTCGCCCATGGCCTCGACTGGCAGGCTGGCGACAACGTCG
TGATCAGCGACGAGGAATTCCCGTCGAACCGCATCGTCTGGGAATCGCTCCGCGCGCGCGGCGTCGAGACGCGCCGCGCA
CGCCTCGCCGCCGCGCCGTCGCCGGAGGATGCGCTCGCCGCGTGCATTGACGCGCGCACGCGGCTGCTTTCGGTCAGCTC
GGTCGAGTACGCGAGCGGACTGCGCCTCGACCTCGATCGCCTGGGCGAGATCTGCCGCGCGCGCGGCGTGCTGTTCTGCG
TCGACGCGATCCAGAGCCTCGGCGTCCTGCCCTTCGATGTCGCGGCATGCGGCGCCGACTTTGTCATGGCCGACGGGCAC
AAGTGGCTGCTCGCCCCCGAGGGCCTGGCGCTGTTCTACGTTCGGCCCGAGATTCGCGACCGGCTCCGGCTCAACCAGTA
CGGCTGGCACATGGTCGAGGAGGCGTTCGATTTCTCGCGCGACGACTGGCAGATTGCCGCGAGCGCGCGCCGCTTCGAAT
GCGGCAGCCCGAACATGCTCGGCATCCACGCGCTGAGCGCGAGCCTAGAAGTACTGGCCGAAGCGGGGACTGCGAACGTC
GCCGCGCAGGTGCTCGCGCACAGCGCGTATTTGATGGACGCACTCGCCGCGCTGCCGGGCATCGAGATACTGACGCCGCG
CGCGCCGGGGCGCTACGCCGGCATCGTGAGCTTTCGCCACGTCCGCGTCGCACCGGTCGAGCTGCACGCCCGCCTGATCG
CGCAGCGCATCCTCTGCGCGCAGCGTGGCGGCGGCGTGCGTTTCTCGCCGCACTTCTACCTCACTCGCGAGCAACTCGAC
ACCGCGGTCGCGGCGGTTGCGGCGGCGACGCGCTGA

Upstream 100 bases:

>100_bases
CGTCATGTCGTATTCCAAGGGTTTTTCTTCAGCCTAGCAAAGCCGCGCAGCCTGGTGAGGCGTCGCGCAAGGCGCGCCTG
CACAGGAAGCGGGCTGTCGT

Downstream 100 bases:

>100_bases
GCCGCGCCGGCTACGCGTCGTCGGCGAGCCGGATGCCCTGGAACTGCCAGCGTTCGTGCGGATAGAAGAAGTTGCGGTAG
CTCGCGCGGATGTGGTCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MIRTVFALGAHPVRAAFLMEENMSDPLTATPAAPAHSLGDEFALDPGLVYLNHAAVAPWPRRTARAVQRFADESLHYGAS
HFPRWMEKEVQLRGQCRDLVNAPSADDIALLKNTSEALSVVAHGLDWQAGDNVVISDEEFPSNRIVWESLRARGVETRRA
RLAAAPSPEDALAACIDARTRLLSVSSVEYASGLRLDLDRLGEICRARGVLFCVDAIQSLGVLPFDVAACGADFVMADGH
KWLLAPEGLALFYVRPEIRDRLRLNQYGWHMVEEAFDFSRDDWQIAASARRFECGSPNMLGIHALSASLEVLAEAGTANV
AAQVLAHSAYLMDALAALPGIEILTPRAPGRYAGIVSFRHVRVAPVELHARLIAQRILCAQRGGGVRFSPHFYLTREQLD
TAVAAVAAATR

Sequences:

>Translated_411_residues
MIRTVFALGAHPVRAAFLMEENMSDPLTATPAAPAHSLGDEFALDPGLVYLNHAAVAPWPRRTARAVQRFADESLHYGAS
HFPRWMEKEVQLRGQCRDLVNAPSADDIALLKNTSEALSVVAHGLDWQAGDNVVISDEEFPSNRIVWESLRARGVETRRA
RLAAAPSPEDALAACIDARTRLLSVSSVEYASGLRLDLDRLGEICRARGVLFCVDAIQSLGVLPFDVAACGADFVMADGH
KWLLAPEGLALFYVRPEIRDRLRLNQYGWHMVEEAFDFSRDDWQIAASARRFECGSPNMLGIHALSASLEVLAEAGTANV
AAQVLAHSAYLMDALAALPGIEILTPRAPGRYAGIVSFRHVRVAPVELHARLIAQRILCAQRGGGVRFSPHFYLTREQLD
TAVAAVAAATR
>Mature_411_residues
MIRTVFALGAHPVRAAFLMEENMSDPLTATPAAPAHSLGDEFALDPGLVYLNHAAVAPWPRRTARAVQRFADESLHYGAS
HFPRWMEKEVQLRGQCRDLVNAPSADDIALLKNTSEALSVVAHGLDWQAGDNVVISDEEFPSNRIVWESLRARGVETRRA
RLAAAPSPEDALAACIDARTRLLSVSSVEYASGLRLDLDRLGEICRARGVLFCVDAIQSLGVLPFDVAACGADFVMADGH
KWLLAPEGLALFYVRPEIRDRLRLNQYGWHMVEEAFDFSRDDWQIAASARRFECGSPNMLGIHALSASLEVLAEAGTANV
AAQVLAHSAYLMDALAALPGIEILTPRAPGRYAGIVSFRHVRVAPVELHARLIAQRILCAQRGGGVRFSPHFYLTREQLD
TAVAAVAAATR

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=330, Percent_Identity=29.0909090909091, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789175, Length=310, Percent_Identity=28.7096774193548, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI48994898, Length=230, Percent_Identity=28.695652173913, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129463, Length=97, Percent_Identity=38.1443298969072, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44831; Mature: 44831

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTVFALGAHPVRAAFLMEENMSDPLTATPAAPAHSLGDEFALDPGLVYLNHAAVAPWP
CCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCC
RRTARAVQRFADESLHYGASHFPRWMEKEVQLRGQCRDLVNAPSADDIALLKNTSEALSV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHH
VAHGLDWQAGDNVVISDEEFPSNRIVWESLRARGVETRRARLAAAPSPEDALAACIDART
HHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHH
RLLSVSSVEYASGLRLDLDRLGEICRARGVLFCVDAIQSLGVLPFDVAACGADFVMADGH
HHEEECCHHHHCCCEECHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCEEEECCC
KWLLAPEGLALFYVRPEIRDRLRLNQYGWHMVEEAFDFSRDDWQIAASARRFECGSPNML
EEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEE
GIHALSASLEVLAEAGTANVAAQVLAHSAYLMDALAALPGIEILTPRAPGRYAGIVSFRH
EHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEE
VRVAPVELHARLIAQRILCAQRGGGVRFSPHFYLTREQLDTAVAAVAAATR
EEECHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRTVFALGAHPVRAAFLMEENMSDPLTATPAAPAHSLGDEFALDPGLVYLNHAAVAPWP
CCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCC
RRTARAVQRFADESLHYGASHFPRWMEKEVQLRGQCRDLVNAPSADDIALLKNTSEALSV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHH
VAHGLDWQAGDNVVISDEEFPSNRIVWESLRARGVETRRARLAAAPSPEDALAACIDART
HHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHH
RLLSVSSVEYASGLRLDLDRLGEICRARGVLFCVDAIQSLGVLPFDVAACGADFVMADGH
HHEEECCHHHHCCCEECHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCEEEECCC
KWLLAPEGLALFYVRPEIRDRLRLNQYGWHMVEEAFDFSRDDWQIAASARRFECGSPNML
EEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEE
GIHALSASLEVLAEAGTANVAAQVLAHSAYLMDALAALPGIEILTPRAPGRYAGIVSFRH
EHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEEE
VRVAPVELHARLIAQRILCAQRGGGVRFSPHFYLTREQLDTAVAAVAAATR
EEECHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]