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The map label for this gene is yciR [C]

Identifier: 74317287

GI number: 74317287

Start: 1333954

End: 1336071

Strand: Direct

Name: yciR [C]

Synonym: Tbd_1269

Alternate gene names: 74317287

Gene position: 1333954-1336071 (Clockwise)

Preceding gene: 74317286

Following gene: 74317291

Centisome position: 45.84

GC content: 67.52

Gene sequence:

>2118_bases
ATGGCCGCTGCGACGCGTATCCTCGTCGCCGACGACGAGCCGACGGCCCGCCTGCTCATGGCGGCCGCCCTCGAGAAGGC
CGGCTTCGAGGTCGCCGTGGCGGTCGACGGCGACGACGCCTTGCGGCAGTTTCGTGCGCAGCCGAGCGCCCTGGTCATGC
TCGACGTCGACATGCCCGGTCGCAACGGCTACGAATTGTGCGCGATCCTGCGCCGCGAATTCGGCGACGAACTGCCGATC
GTGATGGTCACCGCGATGGACGACAACGAGTCGATCGAGCGGGCCTACGAATACGGCGCGACCGATTTCATCCCCAAACC
GATTAACTGGTCGCTCATCGGCCACCGGGTCAAATATCTGCTGCGCGCCTCCGACGCGCTGCGCGAACTGCATGCGGCGA
ATGCCCGCAACGCCGCGCTGCTCAGAGCGATCCCGGATCTCCTGTTCGAAGTCGACGTGGACGGCCGTTACCTCAGTTGC
CATTCCTCGAGGAAAGACCTGCTCGTCGCGCCCGGCGAATCCCTGATCGGACGCACCATCGACGACGTACTTCCGCCCGA
GGCCGCGCGCATCTGCATGGCGGCCTTGCATGAGGCGAACGAGGCCGGGCTGGTGACCGGCAGGCAGTTCGAGTTGATGC
TCGCGTCCGGCGCATTCTGGTTCGAGTTGTCGGTTTCGCGCAAATCCGCCGAGCCCGGACAGAAGCCGACCTTCGTCGTC
CTTGCGCGCAACATCACCGAACGCAAGGCGGCCGAGCAGAAGATATACGAACTCGCCTTCTTCGACAGCCTGACGCATCT
GCCGAACCGGCAGTCGTTTCTCGAGCGGCTCGCGCAGGACATCCGGGTCGCGCAGCGCGAGAAACAGAAGCTCGCCGTCC
TGTTCATGGACCTCGACGGCTTCAAGGGCGTCAACGACACCATGGGTCACGATGCCGGCGACCTGATTCTCCAGTCCGCG
GCCGAGCGGCTGCGAAACAGCATCCGGCCCGGCGACAGCGCGTCGCGCCTGGCCGAAGACGGGGCCCAGGTGGGGCTCGC
GCGCCTGGGGGGCGACGAGTTCACGGCGGTGATCCCGGGGATCACCCATGAGGAGGACGCGTTGCGCGTCGCCAATCGCA
TCCGCGAACAGATGCGCACCCCGTTCGTGCTGGCCGGCAGCGAAGTCGTCCTCACGTCCAGCATCGGCATCGCGGTTTTC
CCGCACGACGGGGCCGACGCGGCGACCCTGCTCAAGCACGCCGACACCGCGATGTACCACGCAAAGAGCTGCGGCCGCGA
CAACTGCCAGTTCTATAGCGCCGCGCTCACGCAGCGTGCGCAGCAGCGGCTGACGCTCGAGAACAACCTGCGTCAGGCGC
TGGAGCGCGGCGAGTTCGACCTCGTCTACCAGCCGCAGATCGACGTCGCGAGCGGGCGTATCCGCTCTGTCGAAGCCCTC
ATCCGCTGGAATCACCCGGCCGGCGGCGTCATCGCGCCGCAGGACTTCATCCCGCTCGCCGAGGAGAACGGCCTCATCGT
GCCGATCGGCGAATGGGCGTTGCGCACGGCCGCGACGGACGCCGCACGCTGGCAGGATGGCGGGCGGGTCTGCGTGGCGG
TCAACCTGTCTCCGGTGCAGCTACGCGCCGCCGACCTCGTCCCGACGCTCGTCGACATCCTGCGCGAGACCGGCCTGGCG
CCGGGCCTGCTCGAACTCGAAGTGACCGAAGGCGCACTGATGGAAGAGCGCGAAGCCACCCACGCGACGCTCGAAGCACT
GCTCGCCGGGGGCGTGCAGCTCGCGCTGGACGATTTCGGTACTGGCTACTCGTCGCTGGGCTATCTCAAGCGTGTGCCGC
TCAGCAACCTCAAGATCGATCAGAGCTTCGTGCACGGGCTGCCGCACGACCGCGAAAATCTGGCGATCGTGCGCACGATC
CTGGCGCTGGCGAAGAATCTCGGTTTCCGCACCACGGCGGAGGGGGTCGAAACGGCCGAGCAGGCCACGACCCTCGCAGG
CATCGGCTGCGACGCGCTGCAGGGCTTTTACTTCAGCCGGCCGCTGCCGGCCGGCGCGATTCCCGCGCTGCTGCAGCGGC
GTTGGCGGCTGGACGAAACCGACCCGGGCGGCGGCTAA

Upstream 100 bases:

>100_bases
AGCGGCGGCTCGACGAGGCGCGCGAAGCGCTCGGCGAAGTACGGGGCGAATACGCTCGCGCGGTATCCGAAATGCACGCG
ATCCTGACGGGAGGACGTTG

Downstream 100 bases:

>100_bases
ACCGTCGTGCTGCCGGATGCGTTCGGTTCGAGCAAATCTTCGCGACGCAGCATGAACACGAACTGGTCGCCGCCTTCGGT
GTCGAGCCAGGTGAAGGGCA

Product: response regulator receiver modulated diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 704

Protein sequence:

>705_residues
MAAATRILVADDEPTARLLMAAALEKAGFEVAVAVDGDDALRQFRAQPSALVMLDVDMPGRNGYELCAILRREFGDELPI
VMVTAMDDNESIERAYEYGATDFIPKPINWSLIGHRVKYLLRASDALRELHAANARNAALLRAIPDLLFEVDVDGRYLSC
HSSRKDLLVAPGESLIGRTIDDVLPPEAARICMAALHEANEAGLVTGRQFELMLASGAFWFELSVSRKSAEPGQKPTFVV
LARNITERKAAEQKIYELAFFDSLTHLPNRQSFLERLAQDIRVAQREKQKLAVLFMDLDGFKGVNDTMGHDAGDLILQSA
AERLRNSIRPGDSASRLAEDGAQVGLARLGGDEFTAVIPGITHEEDALRVANRIREQMRTPFVLAGSEVVLTSSIGIAVF
PHDGADAATLLKHADTAMYHAKSCGRDNCQFYSAALTQRAQQRLTLENNLRQALERGEFDLVYQPQIDVASGRIRSVEAL
IRWNHPAGGVIAPQDFIPLAEENGLIVPIGEWALRTAATDAARWQDGGRVCVAVNLSPVQLRAADLVPTLVDILRETGLA
PGLLELEVTEGALMEEREATHATLEALLAGGVQLALDDFGTGYSSLGYLKRVPLSNLKIDQSFVHGLPHDRENLAIVRTI
LALAKNLGFRTTAEGVETAEQATTLAGIGCDALQGFYFSRPLPAGAIPALLQRRWRLDETDPGGG

Sequences:

>Translated_705_residues
MAAATRILVADDEPTARLLMAAALEKAGFEVAVAVDGDDALRQFRAQPSALVMLDVDMPGRNGYELCAILRREFGDELPI
VMVTAMDDNESIERAYEYGATDFIPKPINWSLIGHRVKYLLRASDALRELHAANARNAALLRAIPDLLFEVDVDGRYLSC
HSSRKDLLVAPGESLIGRTIDDVLPPEAARICMAALHEANEAGLVTGRQFELMLASGAFWFELSVSRKSAEPGQKPTFVV
LARNITERKAAEQKIYELAFFDSLTHLPNRQSFLERLAQDIRVAQREKQKLAVLFMDLDGFKGVNDTMGHDAGDLILQSA
AERLRNSIRPGDSASRLAEDGAQVGLARLGGDEFTAVIPGITHEEDALRVANRIREQMRTPFVLAGSEVVLTSSIGIAVF
PHDGADAATLLKHADTAMYHAKSCGRDNCQFYSAALTQRAQQRLTLENNLRQALERGEFDLVYQPQIDVASGRIRSVEAL
IRWNHPAGGVIAPQDFIPLAEENGLIVPIGEWALRTAATDAARWQDGGRVCVAVNLSPVQLRAADLVPTLVDILRETGLA
PGLLELEVTEGALMEEREATHATLEALLAGGVQLALDDFGTGYSSLGYLKRVPLSNLKIDQSFVHGLPHDRENLAIVRTI
LALAKNLGFRTTAEGVETAEQATTLAGIGCDALQGFYFSRPLPAGAIPALLQRRWRLDETDPGGG
>Mature_704_residues
AAATRILVADDEPTARLLMAAALEKAGFEVAVAVDGDDALRQFRAQPSALVMLDVDMPGRNGYELCAILRREFGDELPIV
MVTAMDDNESIERAYEYGATDFIPKPINWSLIGHRVKYLLRASDALRELHAANARNAALLRAIPDLLFEVDVDGRYLSCH
SSRKDLLVAPGESLIGRTIDDVLPPEAARICMAALHEANEAGLVTGRQFELMLASGAFWFELSVSRKSAEPGQKPTFVVL
ARNITERKAAEQKIYELAFFDSLTHLPNRQSFLERLAQDIRVAQREKQKLAVLFMDLDGFKGVNDTMGHDAGDLILQSAA
ERLRNSIRPGDSASRLAEDGAQVGLARLGGDEFTAVIPGITHEEDALRVANRIREQMRTPFVLAGSEVVLTSSIGIAVFP
HDGADAATLLKHADTAMYHAKSCGRDNCQFYSAALTQRAQQRLTLENNLRQALERGEFDLVYQPQIDVASGRIRSVEALI
RWNHPAGGVIAPQDFIPLAEENGLIVPIGEWALRTAATDAARWQDGGRVCVAVNLSPVQLRAADLVPTLVDILRETGLAP
GLLELEVTEGALMEEREATHATLEALLAGGVQLALDDFGTGYSSLGYLKRVPLSNLKIDQSFVHGLPHDRENLAIVRTIL
ALAKNLGFRTTAEGVETAEQATTLAGIGCDALQGFYFSRPLPAGAIPALLQRRWRLDETDPGGG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=463, Percent_Identity=37.5809935205184, Blast_Score=293, Evalue=3e-80,
Organism=Escherichia coli, GI87081921, Length=448, Percent_Identity=33.2589285714286, Blast_Score=235, Evalue=7e-63,
Organism=Escherichia coli, GI226510982, Length=447, Percent_Identity=31.0961968680089, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI1788502, Length=236, Percent_Identity=36.864406779661, Blast_Score=152, Evalue=9e-38,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=34.6613545816733, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081845, Length=246, Percent_Identity=38.2113821138211, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1787055, Length=263, Percent_Identity=31.1787072243346, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1786507, Length=235, Percent_Identity=34.8936170212766, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=33.6, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=32.3529411764706, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788381, Length=472, Percent_Identity=27.5423728813559, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1788849, Length=446, Percent_Identity=26.457399103139, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87082096, Length=250, Percent_Identity=30.8, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081977, Length=315, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693134, Length=177, Percent_Identity=34.4632768361582, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082007, Length=194, Percent_Identity=29.3814432989691, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=33.9181286549708, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=30.8139534883721, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788394, Length=138, Percent_Identity=37.6811594202899, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787410, Length=231, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787816, Length=187, Percent_Identity=31.5508021390374, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87081881, Length=195, Percent_Identity=31.2820512820513, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=35.8333333333333, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788956, Length=176, Percent_Identity=33.5227272727273, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789809, Length=124, Percent_Identity=33.8709677419355, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=107, Percent_Identity=36.4485981308411, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=30.8823529411765, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 76756; Mature: 76625

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAATRILVADDEPTARLLMAAALEKAGFEVAVAVDGDDALRQFRAQPSALVMLDVDMPG
CCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCC
RNGYELCAILRREFGDELPIVMVTAMDDNESIERAYEYGATDFIPKPINWSLIGHRVKYL
CCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRASDALRELHAANARNAALLRAIPDLLFEVDVDGRYLSCHSSRKDLLVAPGESLIGRTI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEECCCCCCEEEECCHHHHHCCH
DDVLPPEAARICMAALHEANEAGLVTGRQFELMLASGAFWFELSVSRKSAEPGQKPTFVV
HHHCCCHHHHHHHHHHHCCCCCCCEECCEEEEEEECCCEEEEEEECCCCCCCCCCCEEEE
LARNITERKAAEQKIYELAFFDSLTHLPNRQSFLERLAQDIRVAQREKQKLAVLFMDLDG
EECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
FKGVNDTMGHDAGDLILQSAAERLRNSIRPGDSASRLAEDGAQVGLARLGGDEFTAVIPG
CCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECC
ITHEEDALRVANRIREQMRTPFVLAGSEVVLTSSIGIAVFPHDGADAATLLKHADTAMYH
CCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHH
AKSCGRDNCQFYSAALTQRAQQRLTLENNLRQALERGEFDLVYQPQIDVASGRIRSVEAL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHEEEEH
IRWNHPAGGVIAPQDFIPLAEENGLIVPIGEWALRTAATDAARWQDGGRVCVAVNLSPVQ
EEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCE
LRAADLVPTLVDILRETGLAPGLLELEVTEGALMEEREATHATLEALLAGGVQLALDDFG
EEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEHHCC
TGYSSLGYLKRVPLSNLKIDQSFVHGLPHDRENLAIVRTILALAKNLGFRTTAEGVETAE
CCHHHHHHHHCCCCCCCEECHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QATTLAGIGCDALQGFYFSRPLPAGAIPALLQRRWRLDETDPGGG
HHHHHHCCCHHHHHCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AAATRILVADDEPTARLLMAAALEKAGFEVAVAVDGDDALRQFRAQPSALVMLDVDMPG
CCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCC
RNGYELCAILRREFGDELPIVMVTAMDDNESIERAYEYGATDFIPKPINWSLIGHRVKYL
CCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRASDALRELHAANARNAALLRAIPDLLFEVDVDGRYLSCHSSRKDLLVAPGESLIGRTI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEECCCCCCEEEECCHHHHHCCH
DDVLPPEAARICMAALHEANEAGLVTGRQFELMLASGAFWFELSVSRKSAEPGQKPTFVV
HHHCCCHHHHHHHHHHHCCCCCCCEECCEEEEEEECCCEEEEEEECCCCCCCCCCCEEEE
LARNITERKAAEQKIYELAFFDSLTHLPNRQSFLERLAQDIRVAQREKQKLAVLFMDLDG
EECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
FKGVNDTMGHDAGDLILQSAAERLRNSIRPGDSASRLAEDGAQVGLARLGGDEFTAVIPG
CCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECC
ITHEEDALRVANRIREQMRTPFVLAGSEVVLTSSIGIAVFPHDGADAATLLKHADTAMYH
CCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHH
AKSCGRDNCQFYSAALTQRAQQRLTLENNLRQALERGEFDLVYQPQIDVASGRIRSVEAL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHEEEEH
IRWNHPAGGVIAPQDFIPLAEENGLIVPIGEWALRTAATDAARWQDGGRVCVAVNLSPVQ
EEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCE
LRAADLVPTLVDILRETGLAPGLLELEVTEGALMEEREATHATLEALLAGGVQLALDDFG
EEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEHHCC
TGYSSLGYLKRVPLSNLKIDQSFVHGLPHDRENLAIVRTILALAKNLGFRTTAEGVETAE
CCHHHHHHHHCCCCCCCEECHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QATTLAGIGCDALQGFYFSRPLPAGAIPALLQRRWRLDETDPGGG
HHHHHHCCCHHHHHCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]