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The map label for this gene is flhB [H]

Identifier: 74317263

GI number: 74317263

Start: 1306505

End: 1307677

Strand: Direct

Name: flhB [H]

Synonym: Tbd_1245

Alternate gene names: 74317263

Gene position: 1306505-1307677 (Clockwise)

Preceding gene: 74317262

Following gene: 74317264

Centisome position: 44.9

GC content: 67.35

Gene sequence:

>1173_bases
ATGGCTGAAGAAAGCGATCAGGAACGCACAGAAGCCCCGTCGCCACAGCGACTGGAGAAAGCGCGCGAAGAAGGCCAGGT
GCTGCAGTCGCGCGAGCTCGCCACGTTCGTCGTGCTGATGACCGGGGGCGCCGCGCTGTGGGCGATGGCGAGCCAGCTCG
GGCAGACGCTGTCGCAGATCGTGCGCGGCGGCCTGCAGTTCCATCCGGCCGTCGCGCGCGACAGCGCCCACGTGATGACC
CAGCTGTCGCAGCAGTTCTTCGACGCGACCCTCGCGCTGGCGCCTTTCCTGCTCCTGGTTGTGATCGCCACCTTCGCCTC
GCCGATCCTGCTGCGCGGCTGGCTCTTCAGCACCAAGGCCTTCATGCCGGATTTCAAGCGGCTGAGCCCGCTCGCGGGTT
TCAAGCGCATGTTTTCGAGCCAGGGTCTGGTCGAGCTCGTCAAGGCACTGGCCAAGGTCGGTCTGCTCGGCGGCGTTGCC
GCATGGCTCGTCTGGTCGAACGTCGAGGCGATCGTGAGCCTGAGCCTCGAAGCACCCACGGCCGCGATCGGGCACATGGG
CGACATCATCGGCAAGGTCTTCCTGCTCGCCTCGGGCGCGATGATTTTCATCGTCGTGCTCGACCTGCCTTACCAGCTCT
GGAACTTCTACAACAAGCTCAAGATGACCAAGGAGCAGTTGCGCCAGGAAGCGAAGGAGTCGGAAGGCGACCCGCACGTC
AAGGCACGCATCCGCGCCCAGCAGCGCGAAGTCGCGCGACGCCGCATGATGGCCGAAGTTCCCAGCGCCGACGTCGTCGT
CACCAACCCGACCCACTATGCGGTCGCCCTCAAATACAGCGAAGGCAAGATGGGCGCGCCGCGCGTCGTCGCGAAGGGCG
CCGACCTCGTCGCGGCAAAGATCCGCGAGATCGCGGCCGAGCATCGCGTCCCGCTGCTCGAAGCGCCGCCGCTCGCGCGC
GCGCTGTTCCGCCACACCGACATCGGCAACGAGATTCCCGCGACGCTCTACGCGGCCGTCGCCGAGGTGCTCGCCTACGT
GTTCCAGTTGCGGCATTTCGAGAAGGCCGGCGGGGCCTATCCGGCGGCGCCGACGGCCTTGCCCGTCCCGCCCGAACTCG
ACCCGCTGCAGGCGCAGGGCGCGCCTGCCGCTGACATGGGTGCCCAGGCATGA

Upstream 100 bases:

>100_bases
TCCCGCGATCGCCGGCGCGTCCGCCAGCCAATAATCGAGCCTGAAGAAAGTCCCGCCTGCGCACGAGCGCTGGGGCGGCT
CTGCAACAGGTGAGATCGGG

Downstream 100 bases:

>100_bases
ACGGCACGCTGAGTCTATCGAACGTCTTCAGCGCCGCCAACGGCCGCGCCCTCGCGGCGCCGATCTTCATCGTCCTCATT
CTGGCGATGCTCGTGCTGCC

Product: flagellar biosynthetic protein FlhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MAEESDQERTEAPSPQRLEKAREEGQVLQSRELATFVVLMTGGAALWAMASQLGQTLSQIVRGGLQFHPAVARDSAHVMT
QLSQQFFDATLALAPFLLLVVIATFASPILLRGWLFSTKAFMPDFKRLSPLAGFKRMFSSQGLVELVKALAKVGLLGGVA
AWLVWSNVEAIVSLSLEAPTAAIGHMGDIIGKVFLLASGAMIFIVVLDLPYQLWNFYNKLKMTKEQLRQEAKESEGDPHV
KARIRAQQREVARRRMMAEVPSADVVVTNPTHYAVALKYSEGKMGAPRVVAKGADLVAAKIREIAAEHRVPLLEAPPLAR
ALFRHTDIGNEIPATLYAAVAEVLAYVFQLRHFEKAGGAYPAAPTALPVPPELDPLQAQGAPAADMGAQA

Sequences:

>Translated_390_residues
MAEESDQERTEAPSPQRLEKAREEGQVLQSRELATFVVLMTGGAALWAMASQLGQTLSQIVRGGLQFHPAVARDSAHVMT
QLSQQFFDATLALAPFLLLVVIATFASPILLRGWLFSTKAFMPDFKRLSPLAGFKRMFSSQGLVELVKALAKVGLLGGVA
AWLVWSNVEAIVSLSLEAPTAAIGHMGDIIGKVFLLASGAMIFIVVLDLPYQLWNFYNKLKMTKEQLRQEAKESEGDPHV
KARIRAQQREVARRRMMAEVPSADVVVTNPTHYAVALKYSEGKMGAPRVVAKGADLVAAKIREIAAEHRVPLLEAPPLAR
ALFRHTDIGNEIPATLYAAVAEVLAYVFQLRHFEKAGGAYPAAPTALPVPPELDPLQAQGAPAADMGAQA
>Mature_389_residues
AEESDQERTEAPSPQRLEKAREEGQVLQSRELATFVVLMTGGAALWAMASQLGQTLSQIVRGGLQFHPAVARDSAHVMTQ
LSQQFFDATLALAPFLLLVVIATFASPILLRGWLFSTKAFMPDFKRLSPLAGFKRMFSSQGLVELVKALAKVGLLGGVAA
WLVWSNVEAIVSLSLEAPTAAIGHMGDIIGKVFLLASGAMIFIVVLDLPYQLWNFYNKLKMTKEQLRQEAKESEGDPHVK
ARIRAQQREVARRRMMAEVPSADVVVTNPTHYAVALKYSEGKMGAPRVVAKGADLVAAKIREIAAEHRVPLLEAPPLARA
LFRHTDIGNEIPATLYAAVAEVLAYVFQLRHFEKAGGAYPAAPTALPVPPELDPLQAQGAPAADMGAQA

Specific function: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1377

COG function: function code NU; Flagellar biosynthesis pathway, component FlhB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family [H]

Homologues:

Organism=Escherichia coli, GI1788188, Length=374, Percent_Identity=49.7326203208556, Blast_Score=341, Evalue=5e-95,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006136
- InterPro:   IPR006135 [H]

Pfam domain/function: PF01312 Bac_export_2 [H]

EC number: NA

Molecular weight: Translated: 42278; Mature: 42147

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEESDQERTEAPSPQRLEKAREEGQVLQSRELATFVVLMTGGAALWAMASQLGQTLSQI
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VRGGLQFHPAVARDSAHVMTQLSQQFFDATLALAPFLLLVVIATFASPILLRGWLFSTKA
HHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMPDFKRLSPLAGFKRMFSSQGLVELVKALAKVGLLGGVAAWLVWSNVEAIVSLSLEAPT
HCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCH
AAIGHMGDIIGKVFLLASGAMIFIVVLDLPYQLWNFYNKLKMTKEQLRQEAKESEGDPHV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KARIRAQQREVARRRMMAEVPSADVVVTNPTHYAVALKYSEGKMGAPRVVAKGADLVAAK
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCCCHHHHCCHHHHHHH
IREIAAEHRVPLLEAPPLARALFRHTDIGNEIPATLYAAVAEVLAYVFQLRHFEKAGGAY
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAAPTALPVPPELDPLQAQGAPAADMGAQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002587; 11677609; 3298217 [H]