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The map label for this gene is flhA [H]

Identifier: 74317264

GI number: 74317264

Start: 1307674

End: 1309752

Strand: Direct

Name: flhA [H]

Synonym: Tbd_1246

Alternate gene names: 74317264

Gene position: 1307674-1309752 (Clockwise)

Preceding gene: 74317263

Following gene: 74317265

Centisome position: 44.94

GC content: 67.15

Gene sequence:

>2079_bases
ATGAACGGCACGCTGAGTCTATCGAACGTCTTCAGCGCCGCCAACGGCCGCGCCCTCGCGGCGCCGATCTTCATCGTCCT
CATTCTGGCGATGCTCGTGCTGCCGCTGCCGCCGTTCGCGCTCGACCTGCTGTTCACCTTCAACATCGCGCTCTCCATCA
TGGTGCTGCTGGTGAGCCTGTCGACCAAGAAGGCGCTCGACTTCGCCGCCTTCCCGACGGTGCTGCTGCTGTCGACGCTG
CTGCGCCTGTCGCTCAACGTCGCGTCGACGCGCGTGGTCCTGATGCACGGCCATACCGGGCCGGATGCCGCGGGCAAGGT
GATCGAGGCCTTCGGTCACTTCCTCGTGGGCGGCAACTACACGGTCGGCATCATCGTCTTTGTGATCCTCGTGGTCATCA
ACTTCATCGTCATCACCAAAGGTGCCGGGCGCATTGCCGAAGTCAGCGCGCGCTTCACGCTCGACGCGATGCCGGGCAAG
CAGATGGCGATCGACGCCGACCTCAACGCCGGCCTGATCGACGAGAACGAGGCCCGTCGCCGCCGCGCCGAGATAGCGCA
GGAGGCCGACTTCTACGGGTCGATGGACGGTGCGTCGAAATTCGTCCGCGGCGACGCGATCGCCGGCATCCTGATCCTCG
TCATCAACATCGTCGGCGGCCTCGTCATCGGCGTCATACAGCACGATCTGTCGGTCGCCGACTCGGCGAGCAACTACACG
CTGCTTGCGATCGGCGACGGTCTCGTCGCGCAGATCCCCGCGCTCGTGATCTCGATCGCCGCCGGCATCATCGTCAGCCG
CGTCAGTACCGAGGAGGACATCGCCGGGCAGATGCTGTCGAACGTCTTCAGCAAGACGCAGGCGCTCTACATCACTGCGG
CGATCCTCGGCATGATGGGCATGATTCCGGGCATGCCCAACTTCGCGTTTCTGGCGCTGGCCGCCGGAATCGCCTGGCTC
GCCCACAAGGCGCGCGTGCGGCCGCAGGACGCGCCGGCCGAGGTGCAGGCGGCACCCACCGTCGCGCTCGAGTCGCAGGA
GGCGAGCTGGGAGGACGTCGCGCCGATCGACACGCTCGGCCTCGAGGTCGGCTACCGCCTGATCCCGCTCGTCGACAGCA
CGGCCGACGGCGAACTCGTCGGACGCATCAAGGGCATCCGCAAGAAGTTCGCCCGCGAGGTCGGCTTTCTTCCGCCGGCC
GTGCACATCCGCGACAACCTCGAAATCAATCCCAACAGCTATCGCATCACGCTCAAGGGCGTCGAAATCGGCAGCGGCGA
GGTGCGCACCGGCCACTTCCTCGCGATCGACCCGGGCAACGTGGTCACCGCGCTTCCGGGCGTGGCGACGCAGGACCCGG
CGTTCGGCCTGCCGGCGATATGGATCGAACCCGGCCTGCGCGAGCAGGCCCAGGCCATGGGCTACACCGTCGTCGACCCC
GGCACGGTCATCGCCACCCACCTCAACCATCTCGTGACCATGCATGCCGCGGAACTGCTCGGCCGCCAGGAAGCGCAGGC
GCTGCTCGATCACCTCGGGAAAAGCGCGCCCAAGCTCGTCGAAGACCTGGTGCCCAAGCTGCTGTCGCTTTCGGCGGTGC
AGAAGGTCCTGCAGAACCTGCTCACCGAGGGCGTCGCGATCCGCGACATGCGCACTGTCATCGACACGCTGCTCGAACAC
GCGGCGCGGGTCCAGGACCCCAACGAACTCACGGCCCTCGTGCGCGTCGCGCTCGGCCGCTCGATCGTGCAGCAGATCTA
TGGTTCGGCCAACGAGCTCCCGGTGATGACGCTCGATCAGGGCCTCGAGCGTCTGCTGCTGCAGACCCTGCAGGGCGGCC
ACGACGCGGCCGGTCTCGAGCCGGGGCTCGCCGACGCCCTGCTCGAACGCGCGCGGACGAGCACGCAGCGCCAGGAGGCA
CTGGGGCACCCCGCCGTCCTGCTGACGCCGGCCGTGCTGCGGCCGCTGCTCGCCCGTTTCCTGCGGCGCACGGTGCCGCA
ACTCAAGGTGCTTTCGCACGCTGAAGTGCCCGAAGGCAAACAGATCAAAGTGACTTCCCTGGTAGGAGGAGCAGCATGA

Upstream 100 bases:

>100_bases
GCGGGGCCTATCCGGCGGCGCCGACGGCCTTGCCCGTCCCGCCCGAACTCGACCCGCTGCAGGCGCAGGGCGCGCCTGCC
GCTGACATGGGTGCCCAGGC

Downstream 100 bases:

>100_bases
ACGTCAAACGTATCGTCGCCAAAACGTCCCGCGAGGCCATGCGCCAGCTGCGCGACGCACTCGGCCCCGACGCCGTGATC
CTCTCCAATCGCGCGGTCGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MNGTLSLSNVFSAANGRALAAPIFIVLILAMLVLPLPPFALDLLFTFNIALSIMVLLVSLSTKKALDFAAFPTVLLLSTL
LRLSLNVASTRVVLMHGHTGPDAAGKVIEAFGHFLVGGNYTVGIIVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGK
QMAIDADLNAGLIDENEARRRRAEIAQEADFYGSMDGASKFVRGDAIAGILILVINIVGGLVIGVIQHDLSVADSASNYT
LLAIGDGLVAQIPALVISIAAGIIVSRVSTEEDIAGQMLSNVFSKTQALYITAAILGMMGMIPGMPNFAFLALAAGIAWL
AHKARVRPQDAPAEVQAAPTVALESQEASWEDVAPIDTLGLEVGYRLIPLVDSTADGELVGRIKGIRKKFAREVGFLPPA
VHIRDNLEINPNSYRITLKGVEIGSGEVRTGHFLAIDPGNVVTALPGVATQDPAFGLPAIWIEPGLREQAQAMGYTVVDP
GTVIATHLNHLVTMHAAELLGRQEAQALLDHLGKSAPKLVEDLVPKLLSLSAVQKVLQNLLTEGVAIRDMRTVIDTLLEH
AARVQDPNELTALVRVALGRSIVQQIYGSANELPVMTLDQGLERLLLQTLQGGHDAAGLEPGLADALLERARTSTQRQEA
LGHPAVLLTPAVLRPLLARFLRRTVPQLKVLSHAEVPEGKQIKVTSLVGGAA

Sequences:

>Translated_692_residues
MNGTLSLSNVFSAANGRALAAPIFIVLILAMLVLPLPPFALDLLFTFNIALSIMVLLVSLSTKKALDFAAFPTVLLLSTL
LRLSLNVASTRVVLMHGHTGPDAAGKVIEAFGHFLVGGNYTVGIIVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGK
QMAIDADLNAGLIDENEARRRRAEIAQEADFYGSMDGASKFVRGDAIAGILILVINIVGGLVIGVIQHDLSVADSASNYT
LLAIGDGLVAQIPALVISIAAGIIVSRVSTEEDIAGQMLSNVFSKTQALYITAAILGMMGMIPGMPNFAFLALAAGIAWL
AHKARVRPQDAPAEVQAAPTVALESQEASWEDVAPIDTLGLEVGYRLIPLVDSTADGELVGRIKGIRKKFAREVGFLPPA
VHIRDNLEINPNSYRITLKGVEIGSGEVRTGHFLAIDPGNVVTALPGVATQDPAFGLPAIWIEPGLREQAQAMGYTVVDP
GTVIATHLNHLVTMHAAELLGRQEAQALLDHLGKSAPKLVEDLVPKLLSLSAVQKVLQNLLTEGVAIRDMRTVIDTLLEH
AARVQDPNELTALVRVALGRSIVQQIYGSANELPVMTLDQGLERLLLQTLQGGHDAAGLEPGLADALLERARTSTQRQEA
LGHPAVLLTPAVLRPLLARFLRRTVPQLKVLSHAEVPEGKQIKVTSLVGGAA
>Mature_692_residues
MNGTLSLSNVFSAANGRALAAPIFIVLILAMLVLPLPPFALDLLFTFNIALSIMVLLVSLSTKKALDFAAFPTVLLLSTL
LRLSLNVASTRVVLMHGHTGPDAAGKVIEAFGHFLVGGNYTVGIIVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGK
QMAIDADLNAGLIDENEARRRRAEIAQEADFYGSMDGASKFVRGDAIAGILILVINIVGGLVIGVIQHDLSVADSASNYT
LLAIGDGLVAQIPALVISIAAGIIVSRVSTEEDIAGQMLSNVFSKTQALYITAAILGMMGMIPGMPNFAFLALAAGIAWL
AHKARVRPQDAPAEVQAAPTVALESQEASWEDVAPIDTLGLEVGYRLIPLVDSTADGELVGRIKGIRKKFAREVGFLPPA
VHIRDNLEINPNSYRITLKGVEIGSGEVRTGHFLAIDPGNVVTALPGVATQDPAFGLPAIWIEPGLREQAQAMGYTVVDP
GTVIATHLNHLVTMHAAELLGRQEAQALLDHLGKSAPKLVEDLVPKLLSLSAVQKVLQNLLTEGVAIRDMRTVIDTLLEH
AARVQDPNELTALVRVALGRSIVQQIYGSANELPVMTLDQGLERLLLQTLQGGHDAAGLEPGLADALLERARTSTQRQEA
LGHPAVLLTPAVLRPLLARFLRRTVPQLKVLSHAEVPEGKQIKVTSLVGGAA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=689, Percent_Identity=63.5703918722787, Blast_Score=850, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 73377; Mature: 73377

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTLSLSNVFSAANGRALAAPIFIVLILAMLVLPLPPFALDLLFTFNIALSIMVLLVSL
CCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
STKKALDFAAFPTVLLLSTLLRLSLNVASTRVVLMHGHTGPDAAGKVIEAFGHFLVGGNY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
TVGIIVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIDENEARR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCEEEECCCCCCCCCCHHHHH
RRAEIAQEADFYGSMDGASKFVRGDAIAGILILVINIVGGLVIGVIQHDLSVADSASNYT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LLAIGDGLVAQIPALVISIAAGIIVSRVSTEEDIAGQMLSNVFSKTQALYITAAILGMMG
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIPGMPNFAFLALAAGIAWLAHKARVRPQDAPAEVQAAPTVALESQEASWEDVAPIDTLG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHH
LEVGYRLIPLVDSTADGELVGRIKGIRKKFAREVGFLPPAVHIRDNLEINPNSYRITLKG
HHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCCEEEEEEE
VEIGSGEVRTGHFLAIDPGNVVTALPGVATQDPAFGLPAIWIEPGLREQAQAMGYTVVDP
EEECCCCEECCEEEEECCCCEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHCCCEEECC
GTVIATHLNHLVTMHAAELLGRQEAQALLDHLGKSAPKLVEDLVPKLLSLSAVQKVLQNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTEGVAIRDMRTVIDTLLEHAARVQDPNELTALVRVALGRSIVQQIYGSANELPVMTLDQ
HHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHH
GLERLLLQTLQGGHDAAGLEPGLADALLERARTSTQRQEALGHPAVLLTPAVLRPLLARF
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRRTVPQLKVLSHAEVPEGKQIKVTSLVGGAA
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNGTLSLSNVFSAANGRALAAPIFIVLILAMLVLPLPPFALDLLFTFNIALSIMVLLVSL
CCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
STKKALDFAAFPTVLLLSTLLRLSLNVASTRVVLMHGHTGPDAAGKVIEAFGHFLVGGNY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
TVGIIVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIDENEARR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCEEEECCCCCCCCCCHHHHH
RRAEIAQEADFYGSMDGASKFVRGDAIAGILILVINIVGGLVIGVIQHDLSVADSASNYT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LLAIGDGLVAQIPALVISIAAGIIVSRVSTEEDIAGQMLSNVFSKTQALYITAAILGMMG
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIPGMPNFAFLALAAGIAWLAHKARVRPQDAPAEVQAAPTVALESQEASWEDVAPIDTLG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHH
LEVGYRLIPLVDSTADGELVGRIKGIRKKFAREVGFLPPAVHIRDNLEINPNSYRITLKG
HHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCCEEEEEEE
VEIGSGEVRTGHFLAIDPGNVVTALPGVATQDPAFGLPAIWIEPGLREQAQAMGYTVVDP
EEECCCCEECCEEEEECCCCEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHCCCEEECC
GTVIATHLNHLVTMHAAELLGRQEAQALLDHLGKSAPKLVEDLVPKLLSLSAVQKVLQNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTEGVAIRDMRTVIDTLLEHAARVQDPNELTALVRVALGRSIVQQIYGSANELPVMTLDQ
HHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHH
GLERLLLQTLQGGHDAAGLEPGLADALLERARTSTQRQEALGHPAVLLTPAVLRPLLARF
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRRTVPQLKVLSHAEVPEGKQIKVTSLVGGAA
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]