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The map label for this gene is nuoA [H]

Identifier: 74317160

GI number: 74317160

Start: 1197034

End: 1197390

Strand: Direct

Name: nuoA [H]

Synonym: Tbd_1142

Alternate gene names: 74317160

Gene position: 1197034-1197390 (Clockwise)

Preceding gene: 74317159

Following gene: 74317161

Centisome position: 41.14

GC content: 56.02

Gene sequence:

>357_bases
TTGCTGGAAAATTACCTCCCTATTCTGCTGTTCATTTTGGTCGGCCTCGCGTTTGGTATCGGTCCGATCGTGGCCGGCGG
GCTCCTTGCCCCGCATCGGCCGGACAGCGAGAAGCTTTCTCCCTACGAGTGTGGCTTCGAGGCCTTCGAGGATGCGCGGA
TGAAGTTCGACGTGCGCTACTACCTCGTCGCCATTCTGTTCATTCTGTTCGATCTCGAGATCGCTTTTCTGTTTCCCTGG
GCGATTGTGCTTGAGGAGATCGGAATGGCCGGGTTCCTTGCGATGATGGTGTTTCTCGGCATCCTCGTCGTCGGTTTCAT
CTACGAATGGATGAAGGGAGCGCTGGAGTGGGAGTAA

Upstream 100 bases:

>100_bases
AATGCGAGAAATCGCGATTTTTTCGGCTTGACACTCGGCGCTCGCGCCTAATACACTCCCCAGATGATTCAACAGCCTGT
CTAGGCGCGCGGAGGGGCTC

Downstream 100 bases:

>100_bases
GGCCTGTGAGCCCCAGGGCGAGGCGTGGCGCATGAGCATCGAGGGCGTCCTCGAGCAGGGCTTCGTCACCACCAAGGCGG
ACCAGCTCATCAACTACATG

Product: NADH dehydrogenase I subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MLENYLPILLFILVGLAFGIGPIVAGGLLAPHRPDSEKLSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFPW
AIVLEEIGMAGFLAMMVFLGILVVGFIYEWMKGALEWE

Sequences:

>Translated_118_residues
MLENYLPILLFILVGLAFGIGPIVAGGLLAPHRPDSEKLSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFPW
AIVLEEIGMAGFLAMMVFLGILVVGFIYEWMKGALEWE
>Mature_118_residues
MLENYLPILLFILVGLAFGIGPIVAGGLLAPHRPDSEKLSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFPW
AIVLEEIGMAGFLAMMVFLGILVVGFIYEWMKGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=118, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13388; Mature: 13388

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENYLPILLFILVGLAFGIGPIVAGGLLAPHRPDSEKLSPYECGFEAFEDARMKFDVRY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
YLVAILFILFDLEIAFLFPWAIVLEEIGMAGFLAMMVFLGILVVGFIYEWMKGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLENYLPILLFILVGLAFGIGPIVAGGLLAPHRPDSEKLSPYECGFEAFEDARMKFDVRY
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
YLVAILFILFDLEIAFLFPWAIVLEEIGMAGFLAMMVFLGILVVGFIYEWMKGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA