Click here to switch to the map view.

The map label for this gene is grxC1 [H]

Identifier: 74317144

GI number: 74317144

Start: 1180799

End: 1181077

Strand: Direct

Name: grxC1 [H]

Synonym: Tbd_1126

Alternate gene names: 74317144

Gene position: 1180799-1181077 (Clockwise)

Preceding gene: 74317143

Following gene: 74317145

Centisome position: 40.58

GC content: 64.52

Gene sequence:

>279_bases
ATGAATGCCGTCAAGGTCTACAGTACGGGCACCTGCCCGATTTGCGTCAAGGCCAAGGCCTTTCTCGACAAGCGCGGAAT
CGGCTACGACGAGGTCCGCATCGATCTCGACCGCGAGGCGATGAAGGAATTCTCCGTCGTGACCAACGGCGCGCGCACCG
TGCCGCAGATCGTCGTCGACGGCACCTGTATCGGCGGGTTCACCGAACTGACCGAGCTCGACATGGACGGCGGCCTGGAC
CATCTCCACCCCGCATCGCCGGGCGGCCAAGGGGGCTGA

Upstream 100 bases:

>100_bases
CTGCGCGCCGCGAAGTGGGTGCAGGGCCGTGCGCCCGGTCTCTACGACATGCGCGACGTCCTTGGCCTGAAATAGTCAAA
CGTCTGAACAGGAAAACAGC

Downstream 100 bases:

>100_bases
GCGCCGACGCCAAGATTGAAGCCGAAGGGCGGATCGGCTACAATCTCGTGATTCAAGTTCAGGCGGGTTCGCGCAAGCGG
CTCGCCTGAATTTTGTCACC

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 92; Mature: 92

Protein sequence:

>92_residues
MNAVKVYSTGTCPICVKAKAFLDKRGIGYDEVRIDLDREAMKEFSVVTNGARTVPQIVVDGTCIGGFTELTELDMDGGLD
HLHPASPGGQGG

Sequences:

>Translated_92_residues
MNAVKVYSTGTCPICVKAKAFLDKRGIGYDEVRIDLDREAMKEFSVVTNGARTVPQIVVDGTCIGGFTELTELDMDGGLD
HLHPASPGGQGG
>Mature_92_residues
MNAVKVYSTGTCPICVKAKAFLDKRGIGYDEVRIDLDREAMKEFSVVTNGARTVPQIVVDGTCIGGFTELTELDMDGGLD
HLHPASPGGQGG

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=42.6829268292683, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9742; Mature: 9742

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVKVYSTGTCPICVKAKAFLDKRGIGYDEVRIDLDREAMKEFSVVTNGARTVPQIVVD
CCCEEEEECCCCCEEEEHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCEEEEC
GTCIGGFTELTELDMDGGLDHLHPASPGGQGG
CCCCCCCHHHHEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAVKVYSTGTCPICVKAKAFLDKRGIGYDEVRIDLDREAMKEFSVVTNGARTVPQIVVD
CCCEEEEECCCCCEEEEHHHHHHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCEEEEC
GTCIGGFTELTELDMDGGLDHLHPASPGGQGG
CCCCCCCHHHHEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA