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The map label for this gene is cfa [H]

Identifier: 74317065

GI number: 74317065

Start: 1112560

End: 1113729

Strand: Direct

Name: cfa [H]

Synonym: Tbd_1047

Alternate gene names: 74317065

Gene position: 1112560-1113729 (Clockwise)

Preceding gene: 74317064

Following gene: 74317066

Centisome position: 38.23

GC content: 63.76

Gene sequence:

>1170_bases
ATGCAAGAAGAGGAGACGCTGGCGATCGCACCAGCGGGCGCACGCGCGCCAGACGATTCGCCGGCAGTATTGCGTGAACT
CGCAGCCCAAGCCGGCATTACGATAAACGGCGACGCGCCGTGGGACATCCAGGTCCGTGACCCGCGCCTCTACCACCGTA
TTCTGACCAAGGGCTCGCTCGGCTTCGGCGAAGCCTACGTCGACGGCATGTGGGAATGCGACCGCCTCGATCAGCTGTTC
GACCGGTTGCTGAGGATCGACGCCGACGAAAAACTGGGCAGCTGGGCGCGCGTACGGCTATTCGGCGAAGTATTACGCCA
CAGCCTGTTCAATCTTCAATCCGACCGCCGCGCCTTCCAGGTCGCCGAGCAGCACTACGACATCGGCAACGACGTCTTCG
TCGCCATGCTCGACCCGACGATGAGTTACTCATGCGCTTACTGGGACGGCGCGGCCGATCTCGTCGAGGCGCAGCAGAAA
AAGCTCGACATGATCTGCCGGAAACTCGAGTTGAAGCGCGGCGAGGTGCTGCTCGAGATCGGCTGCGGCTGGGGCGGGCT
CGCGCGTTTCGCGGCCGAGCGCTACGGCGTCGAAGTGGTCGGCATCACGGTGTCGAAGGAACAGCAAGCCCTCGCGCGCG
AGCGCTGCAAGGGCCTCCCGGTCGCGATCGAGCTCATGGACTATCGCGAGCTCAGCCGCAAATTCGACAAGATCGTCTCG
GTCGGCATGTTCGAGCACGTCGGCCCCAAGAACTACCGCACGTATTTCGACATCGCCCACCGGGCGCTCAAGAACGATGG
CCTCTTCCTGTTGCATACGATCGGCAGCGCGGTCACCGTCGCGAAGACCGACCCGTGGATCGACCAGTACATCTTTCCCA
ACGGCAAGCTGCCGTCGGCAAGAGAGATCGCGGCGGCGGTCGAGGGCCGCTTCCTGATCGAGGACTGGCACAACTTCGGC
GCCGACTACGACCGCACGCTCATGGCGTGGTGGGAGAAGTTCGACGCCGCCTGGCCCGAGCTGGAAGCCCGATACGGCAC
GCGTTTTTACCGCATGTGGAAATATTACCTGCTGAGTTGCGCCGGCTTTTTCCGATCGCGCCAGGGCCAGCTCTGGCAGG
TGGTGCTGAGCAAGCCGCAGCGCGCCTCGACCTACCGCTCGGTGCGCTGA

Upstream 100 bases:

>100_bases
CTAACGATCGGTTATATCGATAGATAAGTCATAAAAATATCGTTGGTTAAATAGATAGAAATATCTATCTTTTCCCCTGC
AACTTTCGGGGGGAGCCACG

Downstream 100 bases:

>100_bases
CGATCCCTCCTGTCCACCCTGCGCTTGCCGGCCTCGCCGGCGCGCGCCTGCCTTGCCGCCCGGAAGAGACGATCCATGAA
ATTTCCGACCGATTACCTGC

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MQEEETLAIAPAGARAPDDSPAVLRELAAQAGITINGDAPWDIQVRDPRLYHRILTKGSLGFGEAYVDGMWECDRLDQLF
DRLLRIDADEKLGSWARVRLFGEVLRHSLFNLQSDRRAFQVAEQHYDIGNDVFVAMLDPTMSYSCAYWDGAADLVEAQQK
KLDMICRKLELKRGEVLLEIGCGWGGLARFAAERYGVEVVGITVSKEQQALARERCKGLPVAIELMDYRELSRKFDKIVS
VGMFEHVGPKNYRTYFDIAHRALKNDGLFLLHTIGSAVTVAKTDPWIDQYIFPNGKLPSAREIAAAVEGRFLIEDWHNFG
ADYDRTLMAWWEKFDAAWPELEARYGTRFYRMWKYYLLSCAGFFRSRQGQLWQVVLSKPQRASTYRSVR

Sequences:

>Translated_389_residues
MQEEETLAIAPAGARAPDDSPAVLRELAAQAGITINGDAPWDIQVRDPRLYHRILTKGSLGFGEAYVDGMWECDRLDQLF
DRLLRIDADEKLGSWARVRLFGEVLRHSLFNLQSDRRAFQVAEQHYDIGNDVFVAMLDPTMSYSCAYWDGAADLVEAQQK
KLDMICRKLELKRGEVLLEIGCGWGGLARFAAERYGVEVVGITVSKEQQALARERCKGLPVAIELMDYRELSRKFDKIVS
VGMFEHVGPKNYRTYFDIAHRALKNDGLFLLHTIGSAVTVAKTDPWIDQYIFPNGKLPSAREIAAAVEGRFLIEDWHNFG
ADYDRTLMAWWEKFDAAWPELEARYGTRFYRMWKYYLLSCAGFFRSRQGQLWQVVLSKPQRASTYRSVR
>Mature_389_residues
MQEEETLAIAPAGARAPDDSPAVLRELAAQAGITINGDAPWDIQVRDPRLYHRILTKGSLGFGEAYVDGMWECDRLDQLF
DRLLRIDADEKLGSWARVRLFGEVLRHSLFNLQSDRRAFQVAEQHYDIGNDVFVAMLDPTMSYSCAYWDGAADLVEAQQK
KLDMICRKLELKRGEVLLEIGCGWGGLARFAAERYGVEVVGITVSKEQQALARERCKGLPVAIELMDYRELSRKFDKIVS
VGMFEHVGPKNYRTYFDIAHRALKNDGLFLLHTIGSAVTVAKTDPWIDQYIFPNGKLPSAREIAAAVEGRFLIEDWHNFG
ADYDRTLMAWWEKFDAAWPELEARYGTRFYRMWKYYLLSCAGFFRSRQGQLWQVVLSKPQRASTYRSVR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=367, Percent_Identity=58.0381471389646, Blast_Score=439, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI133904226, Length=370, Percent_Identity=31.0810810810811, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 44544; Mature: 44544

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEEETLAIAPAGARAPDDSPAVLRELAAQAGITINGDAPWDIQVRDPRLYHRILTKGSL
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEEECCCCCEEEEECCHHHHHHHHHCCCC
GFGEAYVDGMWECDRLDQLFDRLLRIDADEKLGSWARVRLFGEVLRHSLFNLQSDRRAFQ
CCCHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHH
VAEQHYDIGNDVFVAMLDPTMSYSCAYWDGAADLVEAQQKKLDMICRKLELKRGEVLLEI
HHHHHCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GCGWGGLARFAAERYGVEVVGITVSKEQQALARERCKGLPVAIELMDYRELSRKFDKIVS
CCCCHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
VGMFEHVGPKNYRTYFDIAHRALKNDGLFLLHTIGSAVTVAKTDPWIDQYIFPNGKLPSA
HHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCHHHHCCCCCCCCCH
REIAAAVEGRFLIEDWHNFGADYDRTLMAWWEKFDAAWPELEARYGTRFYRMWKYYLLSC
HHHHHHHCCCEEEEHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AGFFRSRQGQLWQVVLSKPQRASTYRSVR
HHHHHCCCCHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure
MQEEETLAIAPAGARAPDDSPAVLRELAAQAGITINGDAPWDIQVRDPRLYHRILTKGSL
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEEECCCCCEEEEECCHHHHHHHHHCCCC
GFGEAYVDGMWECDRLDQLFDRLLRIDADEKLGSWARVRLFGEVLRHSLFNLQSDRRAFQ
CCCHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHH
VAEQHYDIGNDVFVAMLDPTMSYSCAYWDGAADLVEAQQKKLDMICRKLELKRGEVLLEI
HHHHHCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GCGWGGLARFAAERYGVEVVGITVSKEQQALARERCKGLPVAIELMDYRELSRKFDKIVS
CCCCHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
VGMFEHVGPKNYRTYFDIAHRALKNDGLFLLHTIGSAVTVAKTDPWIDQYIFPNGKLPSA
HHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCHHHHCCCCCCCCCH
REIAAAVEGRFLIEDWHNFGADYDRTLMAWWEKFDAAWPELEARYGTRFYRMWKYYLLSC
HHHHHHHCCCEEEEHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AGFFRSRQGQLWQVVLSKPQRASTYRSVR
HHHHHCCCCHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]